Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 77 件
2BO4
DownloadVisualize
BU of 2bo4 by Molmil
Dissection of mannosylglycerate synthase: an archetypal mannosyltransferase
分子名称: CITRATE ANION, MANNOSYLGLYCERATE SYNTHASE
著者Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J.
登録日2005-04-07
公開日2005-06-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Dissection and High-Throughput Screening of Mannosylglyceerate Synthase
Nat.Struct.Mol.Biol., 12, 2005
4QYP
DownloadVisualize
BU of 4qyp by Molmil
The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinal
分子名称: ACETATE ION, RETINAL, Retinol-binding protein 2
著者Nossoni, Z, Assar, Z, Yapici, I, Nosrati, M, Wang, W, Berbasova, T, Vasileiou, C, Borhan, B, Geiger, H.
登録日2014-07-25
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structures of holo wild-type human cellular retinol-binding protein II (hCRBPII) bound to retinol and retinal.
Acta Crystallogr.,Sect.D, 70, 2014
2BO7
DownloadVisualize
BU of 2bo7 by Molmil
DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE
分子名称: COBALT (II) ION, GUANOSINE-5'-DIPHOSPHATE, MANNOSYLGLYCERATE SYNTHASE
著者Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J.
登録日2005-04-08
公開日2005-06-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural dissection and high-throughput screening of mannosylglycerate synthase.
Nat. Struct. Mol. Biol., 12, 2005
1E95
DownloadVisualize
BU of 1e95 by Molmil
Solution structure of the pseudoknot of SRV-1 RNA, involved in ribosomal frameshifting
分子名称: RNA (5'-(*GP*CP*GP*GP*CP*CP*AP*GP*CP*UP*CP* CP*AP*GP*GP*CP*CP*GP*CP*CP*AP*AP*AP*CP* AP*AP*UP*AP*UP*GP*GP*AP*GP*CP*AP*C)-3')
著者Michiels, P.J.A, Versleyen, A, Pleij, C.W.A, Hilbers, C.W, Heus, H.A.
登録日2000-10-09
公開日2001-08-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of the Pseudoknot of Srv-1 RNA, Involved in Ribosomal Frameshifting
J.Mol.Biol., 310, 2001
2BO6
DownloadVisualize
BU of 2bo6 by Molmil
DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE
分子名称: (2R)-2,3-DIHYDROXYPROPANOIC ACID, MANGANESE (II) ION, MANNOSYLGLYCERATE SYNTHASE
著者Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J.
登録日2005-04-08
公開日2005-06-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural Dissection and High-Throughput Screening of Mannosylglyceerate Synthase
Nat.Struct.Mol.Biol., 12, 2005
4XYC
DownloadVisualize
BU of 4xyc by Molmil
NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES
分子名称: 9-phenyl-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one, Glutamine synthetase 1
著者Couturier, C, Silve, S, Morales, R, Ppessegue, B, Llopart, S, Nair, A, Bauer, A, Scheiper, B, poeverlein, c, Ganzhorn, A, Lagrange, S, Bacque, E.
登録日2015-02-02
公開日2015-03-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Nanomolar inhibitors of Mycobacterium tuberculosis glutamine synthetase 1: Synthesis, biological evaluation and X-ray crystallographic studies.
Bioorg.Med.Chem.Lett., 25, 2015
2IV3
DownloadVisualize
BU of 2iv3 by Molmil
Crystal structure of AviGT4, a glycosyltransferase involved in Avilamycin A biosynthesis
分子名称: GLYCEROL, GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE
著者Martinez-Fleites, C, Proctor, M, Roberts, S, Bolam, D.N, Gilbert, H.J, Davies, G.J.
登録日2006-06-08
公開日2006-10-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insights Into the Synthesis of Lipopolysaccharide and Antibiotics Through the Structures of Two Retaining Glycosyltransferases from Family Gt4
Chem.Biol., 13, 2006
2W4X
DownloadVisualize
BU of 2w4x by Molmil
BtGH84 in complex with STZ
分子名称: CALCIUM ION, GLYCEROL, O-GLCNACASE BT_4395, ...
著者He, Y, Bubb, A, Martinez-Fleites, C, Davies, G.J.
登録日2008-12-02
公開日2009-02-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural Insight Into the Mechanism of Streptozotocin Inhibition of O-Glcnacase.
Carbohydr.Res., 344, 2009
4ZJ0
DownloadVisualize
BU of 4zj0 by Molmil
The crystal structure of monomer Q108K:K40L:Y60W CRBPII bound to all-trans-retinal
分子名称: ACETATE ION, RETINAL, Retinol-binding protein 2
著者Nossoni, Z, Assar, Z, Wang, W, Vasileiou, C, Borhan, B, Geiger, J.H.
登録日2015-04-28
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates.
Structure, 24, 2016
2VVS
DownloadVisualize
BU of 2vvs by Molmil
BtGH84 structure in complex with PUGNAc
分子名称: O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, O-GLCNACASE BT_4395
著者Macauley, M.S, Bubb, A, Martinez-Fleites, C, Davies, G.J, Vocadlo, D.J.
登録日2008-06-11
公開日2008-09-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Elevation of Global O-Glcnac Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-Glcnacase Does not Induce Insulin Resistance
J.Biol.Chem., 283, 2008
1UYW
DownloadVisualize
BU of 1uyw by Molmil
Crystal Structure of the antiflavivirus Fab4g2
分子名称: FAB ANTIBODY HEAVY CHAIN, FAB ANTIBODY LIGHT CHAIN
著者Martinez-Fleites, C, Ortiz-Lombardia, M, Taylor, E.J, Gil-Valdes, J, Chinea, G, Davies, G.
登録日2004-03-03
公開日2005-03-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Antiflavivirus Fab4G2
To be Published
2IYA
DownloadVisualize
BU of 2iya by Molmil
The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering
分子名称: (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-14-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}-1,9-DIOXASPIRO[2.13]HEXADEC-12-YL 2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE, OLEANDOMYCIN GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE
著者Bolam, D.N, Roberts, S.M, Proctor, M.R, Turkenburg, J.P, Dodson, E.J, Martinez-Fleites, C, Yang, M, Davis, B.G, Davies, G.J, Gilbert, H.J.
登録日2006-07-13
公開日2007-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity.
Proc.Natl.Acad.Sci.USA, 104, 2007
2IYF
DownloadVisualize
BU of 2iyf by Molmil
The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering
分子名称: ERYTHROMYCIN A, MAGNESIUM ION, OLEANDOMYCIN GLYCOSYLTRANSFERASE, ...
著者Bolam, D.N, Roberts, S.M, Proctor, M.R, Turkenburg, J.P, Dodson, E.J, Martinez-Fleites, C, Yang, M, Davis, B.G, Davies, G.J, Gilbert, H.J.
登録日2006-07-17
公開日2007-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity.
Proc.Natl.Acad.Sci.USA, 104, 2007
2IW1
DownloadVisualize
BU of 2iw1 by Molmil
Crystal Structure of WaaG, a glycosyltransferase involved in lipopolysaccharide biosynthesis
分子名称: LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS PROTEIN RFAG, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE
著者Martinez-Fleites, C, Proctor, M, Roberts, S, Bolam, D.N, Gilbert, H.J, Davies, G.J.
登録日2006-06-23
公開日2006-10-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Insights Into the Synthesis of Lipopolysaccharide and Antibiotics Through the Structures of Two Retaining Glycosyltransferases from Family Gt4
Chem.Biol., 13, 2006
2IUY
DownloadVisualize
BU of 2iuy by Molmil
Crystal structure of AviGT4, a glycosyltransferase involved in Avilamycin A biosynthesis
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCOSYLTRANSFERASE, SULFATE ION
著者Martinez-Fleites, C, Proctor, M, Roberts, S, Bolam, D.N, Gilbert, H.J, Davies, G.J.
登録日2006-06-08
公開日2006-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights Into the Synthesis of Lipopolysaccharide and Antibiotics Through the Structures of Two Retaining Glycosyltransferases from Family Gt4
Chem.Biol., 13, 2006
2WAG
DownloadVisualize
BU of 2wag by Molmil
The Structure of a family 25 Glycosyl hydrolase from Bacillus anthracis.
分子名称: GLYCEROL, LYSOZYME, PUTATIVE, ...
著者Martinez-Fleites, C, Korczynska, J.E, Cope, M, Turkenburg, J.P, Taylor, E.J.
登録日2009-02-06
公開日2009-06-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The Crystal Structure of a Family Gh25 Lysozyme from Bacillus Anthracis Implies a Neighboring-Group Catalytic Mechanism with Retention of Anomeric Configuration
Carbohydr.Res., 344, 2009
2IV7
DownloadVisualize
BU of 2iv7 by Molmil
Crystal Structure of WaaG, a glycosyltransferase involved in lipopolysaccharide biosynthesis
分子名称: LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS PROTEIN RFAG, URIDINE-5'-DIPHOSPHATE
著者Martinez-Fleites, C, Proctor, M, Roberts, S, Bolam, D.N, Gilbert, H.J, Davies, G.J.
登録日2006-06-08
公開日2006-10-11
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Insights Into the Synthesis of Lipopolysaccharide and Antibiotics Through the Structures of Two Retaining Glycosyltransferases from Family Gt4
Chem.Biol., 13, 2006
1GAR
DownloadVisualize
BU of 1gar by Molmil
TOWARDS STRUCTURE-BASED DRUG DESIGN: CRYSTAL STRUCTURE OF A MULTISUBSTRATE ADDUCT COMPLEX OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE AT 1.96 ANGSTROMS RESOLUTION
分子名称: GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, N-[4-[[3-(2,4-DIAMINO-1,6-DIHYDRO-6-OXO-4-PYRIMIDINYL)-PROPYL]-[2-((2-OXO-2-((4-PHOSPHORIBOXY)-BUTYL)-AMINO)-ETHYL)-THIO-ACETYL]-AMINO]BENZOYL]-1-GLUTAMIC ACID
著者Wilson, I.A, Klein, C, Chen, P, Arevalo, J.H.
登録日1994-12-08
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution.
J.Mol.Biol., 249, 1995
4LI5
DownloadVisualize
BU of 4li5 by Molmil
EGFR-K IN COMPLEX WITH N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxy-phenyl] Prop-2-enamide
分子名称: Epidermal growth factor receptor, N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamide, SODIUM ION
著者Debreczeni, J.E, Seiffert, G.B, Kiefersauer, R, Augustin, M, Nagel, S, Ward, R, Anderton, M, Ashton, S, Bethel, P, Box, M, Butterworth, S, Colclough, N, Chroley, C, Chuaqui, C, Cross, D, Eberlein, C, Finlay, R, Hill, G, Grist, M, Klinowska, T, Lane, C, Martin, S, Orme, J, Smith, P, Wang, F, Waring, M.
登録日2013-07-02
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR).
J.Med.Chem., 56, 2013
4QYN
DownloadVisualize
BU of 4qyn by Molmil
The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinol
分子名称: ACETATE ION, RETINOL, Retinol-binding protein 2
著者Nossoni, Z, Assar, Z, Yapici, I, Nosrati, M, Wang, W, Berbasova, T, Vasileiou, C, Borhan, B, Geiger, H.
登録日2014-07-24
公開日2014-12-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Structures of holo wild-type human cellular retinol-binding protein II (hCRBPII) bound to retinol and retinal.
Acta Crystallogr.,Sect.D, 70, 2014
8B7H
DownloadVisualize
BU of 8b7h by Molmil
Crystal structure of human Gremlin-1 in complex with Fab
分子名称: Fab antibody fragment (heavy chain), Fab antibody fragment (light chain), Gremlin-1
著者Schulze, M.-S, Martinez-Fleites, C.
登録日2022-09-30
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery of ginisortamab, a potent and novel anti-gremlin-1 antibody in clinical development for the treatment of cancer.
Mabs, 15, 2023
6S5A
DownloadVisualize
BU of 6s5a by Molmil
CRYSTAL STRUCTURE OF FC P329G LALA WITH ANTI FC P329G FAB
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fc P329G LALA, ...
著者Ehler, A, Darowski, D, Jost, C, Stubenrauch, K, Wessels, U, Benz, J, Birk, M, Freimoser-Grundschober, A, Bruenker, P, Moessner, E, Umana, P, Kobold, S, Klein, C.
登録日2019-07-01
公開日2019-09-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献P329G-CAR-J: a novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation.
Protein Eng.Des.Sel., 32, 2019
4MC9
DownloadVisualize
BU of 4mc9 by Molmil
HIV protease in complex with AA74
分子名称: (3S)-tetrahydrofuran-3-yl {(2S,3R)-4-[(4R)-7-fluoro-1,1-dioxido-4-(propan-2-yl)-4,5-dihydro-1,2-benzothiazepin-2(3H)-yl]-3-hydroxy-1-phenylbutan-2-yl}carbamate, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Ganguly, A.K, Alluri, S.S, Wang, C, Antropow, A, White, A, Caroccia, D, Biswas, D, Kang, E, Zhang, L, Carroll, S.S, Burlein, C, Munshi, V, Orth, P, Strickland, C.
登録日2013-08-21
公開日2014-04-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Structural Optimization of Cyclic Sulfonamide based Novel HIV-1 Protease Inhibitors to Pico Molar Affinities guided by X-ray Crystallographic Analysis
Tetrahedron, 2014
3PHP
DownloadVisualize
BU of 3php by Molmil
STRUCTURE OF THE 3' HAIRPIN OF THE TYMV PSEUDOKNOT: PREFORMATION IN RNA FOLDING
分子名称: RNA (5'-R(*GP*GP*UP*UP*CP*CP*GP*AP*GP*GP*GP*UP*CP*AP*UP*CP*GP*GP*AP*AP*CP*CP*A) -3')
著者Kolk, M.H, Van Der Graaf, M, Wijmenga, S.S, Pleij, C.W.A, Heus, H.A, Hilbers, C.W.
登録日1998-10-13
公開日1998-10-21
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of the 3'-hairpin of the TYMV pseudoknot: preformation in RNA folding.
EMBO J., 17, 1998
4MC2
DownloadVisualize
BU of 4mc2 by Molmil
HIV protease in complex with SA525P
分子名称: (3S)-tetrahydrofuran-3-yl {(2S,3R)-4-[(4R)-4-tert-butyl-7-fluoro-1,1-dioxido-4,5-dihydro-1,2-benzothiazepin-2(3H)-yl]-3-hydroxy-1-phenylbutan-2-yl}carbamate, CHLORIDE ION, Protease
著者Ganguly, A.K, Alluri, S.S, Wang, C, Caroccia, D, Biswas, D, Kang, E, Zhang, L, Carroll, S.S, Burlein, C, Munshi, V, Orth, P, Strickland, C.
登録日2013-08-21
公開日2014-04-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Structural Optimization of Cyclic Sulfonamide based Novel HIV-1 Protease Inhibitors to Pico Molar Affinities guided by X-ray Crystallographic Analysis
Tetrahedron, 2014

222624

件を2024-07-17に公開中

PDB statisticsPDBj update infoContact PDBjnumon