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PDB: 302 results

4P2H
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BU of 4p2h by Molmil
Structure of human DNA polymerase complexed with N7MG in the template opposite to incoming non-hydrolyzable TTP with manganese in the active site
Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Lee, S, Koag, M.C.
Deposit date:2014-03-04
Release date:2014-06-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.987 Å)
Cite:Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res., 42, 2014
6PGQ
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BU of 6pgq by Molmil
Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (22-32)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Calcitonin, ...
Authors:Lee, S, Pioszak, A.A.
Deposit date:2019-06-24
Release date:2020-02-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics.
J.Mol.Biol., 432, 2020
5IP5
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BU of 5ip5 by Molmil
Human DJ-1 complexed with Na-K-tartrate
Descriptor: L(+)-TARTARIC ACID, Protein deglycase DJ-1
Authors:Lee, S, Cha, S.-S, An, Y.J.
Deposit date:2016-03-09
Release date:2017-03-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Human DJ-1 complexed with Na-K-tartrate
To Be Published
6PFO
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BU of 6pfo by Molmil
Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (16-32)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcitonin, Maltodextrin-binding protein,Calcitonin receptor, ...
Authors:Lee, S, Pioszak, A.A.
Deposit date:2019-06-21
Release date:2020-02-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics.
J.Mol.Biol., 432, 2020
6MEV
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BU of 6mev by Molmil
Structure of JMJD6 bound to Mono-Methyl Arginine.
Descriptor: (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, 2-OXOGLUTARIC ACID, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, ...
Authors:Lee, S, Zhang, G.
Deposit date:2018-09-07
Release date:2019-09-18
Last modified:2020-04-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes.
Elife, 9, 2020
3CRA
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BU of 3cra by Molmil
Crystal Structure of Escherichia coli MazG, the Regulator of Nutritional Stress Response
Descriptor: Protein mazG
Authors:Lee, S, Kim, M.H, Kang, B.S, Kim, J.S, Kim, Y.G, Kim, K.J.
Deposit date:2008-04-05
Release date:2008-04-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Escherichia coli MazG, the regulator of nutritional stress response.
J.Biol.Chem., 283, 2008
3G0Q
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BU of 3g0q by Molmil
Crystal Structure of MutY bound to its inhibitor DNA
Descriptor: 5'-D(*AP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*CP*AP*GP*TP*CP*TP*T)-3', A/G-specific adenine glycosylase, ...
Authors:Lee, S, Verdine, G.L.
Deposit date:2009-01-28
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase.
Proc.Natl.Acad.Sci.Usa, 106, 2009
3EVK
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BU of 3evk by Molmil
Crystal structure of the metal-bound superoxide dismutase from Pyrobaculum aerophilum
Descriptor: MANGANESE (II) ION, Superoxide dismutase [Fe]
Authors:Lee, S.
Deposit date:2008-10-13
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Metal-bound Superoxide Dismutase from Pyrobaculum aerophilum and Comparison with the Metal-free Form
Bull.Korean Chem.Soc., 29, 2008
2KMK
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BU of 2kmk by Molmil
Gfi-1 Zinc Fingers 3-5 complexed with DNA
Descriptor: DNA (5'-D(*CP*AP*TP*AP*AP*AP*TP*CP*AP*CP*TP*GP*CP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*GP*CP*AP*GP*TP*GP*AP*TP*TP*TP*AP*TP*G)-3'), ZINC ION, ...
Authors:Lee, S, Wu, Z.
Deposit date:2009-07-30
Release date:2010-03-02
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of Gfi-1 zinc domain bound to consensus DNA.
J.Mol.Biol., 397, 2010
5CUS
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BU of 5cus by Molmil
Crystal Structure of sErbB3-Fab3379 Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab LC region of KTN3379, IgG H chain, ...
Authors:Lee, S, Schlessinger, J.
Deposit date:2015-07-25
Release date:2015-10-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration.
Proc.Natl.Acad.Sci.USA, 112, 2015
3PMR
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BU of 3pmr by Molmil
Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1
Descriptor: Amyloid-like protein 1, PHOSPHATE ION
Authors:Lee, S, Xue, Y, Hu, J, Wang, Y, Liu, X, Demeler, B, Ha, Y.
Deposit date:2010-11-17
Release date:2011-06-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization.
Biochemistry, 50, 2011
5XD8
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BU of 5xd8 by Molmil
Crystal structure analysis of 3,6-anhydro-L-galactonate cycloisomerase
Descriptor: 3,6-anhydro-alpha-L-galactonate cycloisomerase, MAGNESIUM ION
Authors:Lee, S, Choi, I.-G, Kim, H.-Y.
Deposit date:2017-03-27
Release date:2017-09-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.505 Å)
Cite:Crystal structure analysis of 3,6-anhydro-l-galactonate cycloisomerase suggests emergence of novel substrate specificity in the enolase superfamily
Biochem. Biophys. Res. Commun., 491, 2017
3DAK
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BU of 3dak by Molmil
Crystal Structure of Domain-Swapped OSR1 kinase domain
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase OSR1
Authors:Lee, S, Cobb, M.H, Goldsmith, E.J.
Deposit date:2008-05-29
Release date:2009-02-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of domain-swapped STE20 OSR1 kinase domain.
Protein Sci., 18, 2008
5XD7
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BU of 5xd7 by Molmil
Crystal structure analysis of 3,6-anhydro-L-galactonate cycloisomerase
Descriptor: 3,6-anhydro-alpha-L-galactonate cycloisomerase, ACETIC ACID, MAGNESIUM ION
Authors:Lee, S, Choi, I.-G, Kim, H.-Y.
Deposit date:2017-03-27
Release date:2017-09-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Crystal structure analysis of 3,6-anhydro-l-galactonate cycloisomerase suggests emergence of novel substrate specificity in the enolase superfamily.
Biochem. Biophys. Res. Commun., 491, 2017
5XD9
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BU of 5xd9 by Molmil
Crystal structure analysis of 3,6-anhydro-L-galactonate cycloisomerase
Descriptor: 3,6-anhydro-alpha-L-galactonate cycloisomerase, MAGNESIUM ION
Authors:Lee, S, Choi, I.-G, Kim, H.-Y.
Deposit date:2017-03-27
Release date:2017-09-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure analysis of 3,6-anhydro-l-galactonate cycloisomerase suggests emergence of novel substrate specificity in the enolase superfamily
Biochem. Biophys. Res. Commun., 491, 2017
2FID
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BU of 2fid by Molmil
Crystal Structure of a Bovine Rabex-5 fragment complexed with ubiquitin
Descriptor: Rab5 GDP/GTP exchange factor, Ubiquitin, ZINC ION
Authors:Lee, S, Hurley, J.H.
Deposit date:2005-12-29
Release date:2006-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
Nat.Struct.Mol.Biol., 13, 2006
4HWL
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BU of 4hwl by Molmil
Crystal Structure Analysis of the Bacteriorhodopsin in Facial Amphiphile-7 DMPC Bicelle
Descriptor: Bacteriorhodopsin, GLYCEROL, HEPTANE, ...
Authors:Lee, S, Stout, C.D, Zhang, Q.
Deposit date:2012-11-08
Release date:2013-03-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HYX
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BU of 4hyx by Molmil
Crystal Structure Analysis of the Bacteriorhodopsin in Facial Amphiphile-4 DMPC Bicelle
Descriptor: Bacteriorhodopsin, DECANE, GLYCEROL, ...
Authors:Lee, S, Stout, C.D, Zhang, Q.
Deposit date:2012-11-14
Release date:2013-03-20
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins.
Proc.Natl.Acad.Sci.USA, 110, 2013
2OJQ
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BU of 2ojq by Molmil
Crystal structure of Alix V domain
Descriptor: Programmed cell death 6-interacting protein
Authors:Lee, S, Hurley, J.H.
Deposit date:2007-01-13
Release date:2007-02-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural basis for viral late-domain binding to Alix
Nat.Struct.Mol.Biol., 14, 2007
2FIF
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BU of 2fif by Molmil
Crystal Structure of a Bovine Rabex-5 fragment complexed with ubiquitin
Descriptor: Rab5 GDP/GTP exchange factor, SULFATE ION, Ubiquitin, ...
Authors:Lee, S, Hurley, J.H.
Deposit date:2005-12-29
Release date:2006-02-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
Nat.Struct.Mol.Biol., 13, 2006
4CST
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BU of 4cst by Molmil
Crystal structure of FimH in complex with 3'-Chloro-4'-(alpha-D-mannopyranosyloxy)-biphenyl-4-carbonitrile
Descriptor: 3'-chloro-4'-(alpha-D-mannopyranosyloxy)biphenyl-4-carbonitrile, PROTEIN FIMH
Authors:Kleeb, S, Pang, L, Mayer, K, Sigl, A, Eris, D, Preston, R.C, Zihlmann, P, Abgottspon, D, Hutter, A, Scharenberg, M, Jian, X, Navarra, G, Rabbani, S, Smiesko, M, Luedin, N, Jakob, R.P, Schwardt, O, Maier, T, Sharpe, T, Ernst, B.
Deposit date:2014-03-10
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Fimh Antagonists: Bioisosteres to Improve the in Vitro and in Vivo Pk/Pd Profile.
J.Med.Chem., 58, 2015
4CSS
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BU of 4css by Molmil
Crystal structure of FimH in complex with a sulfonamide biphenyl alpha D-mannoside
Descriptor: 4'-(alpha-D-Mannopyranosyloxy)-biphenyl-4-methyl sulfonamide, GLYCEROL, PROTEIN FIMH
Authors:Kleeb, S, Pang, L, Mayer, K, Sigl, A, Eris, D, Preston, R.C, Zihlmann, P, Abgottspon, D, Hutter, A, Scharenberg, M, Jian, X, Navarra, G, Rabbani, S, Smiesko, M, Luedin, N, Jakob, R.P, Schwardt, O, Maier, T, Sharpe, T, Ernst, B.
Deposit date:2014-03-10
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.069 Å)
Cite:Fimh Antagonists: Bioisosteres to Improve the in Vitro and in Vivo Pk/Pd Profile.
J.Med.Chem., 58, 2015
3CVT
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BU of 3cvt by Molmil
Crystal Structure of an AlkA Host/Guest Complex 8oxoGuanine:Cytosine Base Pair
Descriptor: DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*(8OG)P*DAP*DGP*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DCP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), DNA-3-methyladenine glycosylase 2
Authors:Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
Deposit date:2008-04-19
Release date:2008-09-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Structure, 16, 2008
3L7U
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BU of 3l7u by Molmil
Crystal structure of human NM23-H1
Descriptor: Nucleoside diphosphate kinase A, PHOSPHATE ION
Authors:Han, B.G, Min, K, Lee, B.I, Lee, S.
Deposit date:2009-12-29
Release date:2010-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refined Structure of Human NM23-H1 from a Hexagonal Crystal
BULL.KOREAN CHEM.SOC., 31, 2010
3C9B
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BU of 3c9b by Molmil
Crystal structure of SeMet Vps75
Descriptor: Vacuolar protein sorting-associated protein 75
Authors:Keck, J.L, Berndsen, C.E, Tsubota, T, Lindner, S.E, Lee, S, Holton, J.M, Kaufman, P.D, Denu, J.M.
Deposit date:2008-02-15
Release date:2008-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75
Nat.Struct.Mol.Biol., 15, 2008

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