3CVT

Crystal Structure of an AlkA Host/Guest Complex 8oxoGuanine:Cytosine Base Pair

Summary for 3CVT

• Entry DOI: 10.2210/pdb3cvt/pdb
• Related: 3CVS 3CW7 3CWA 3CWS 3CWT 3CWU
• Descriptor: DNA-3-methyladenine glycosylase 2, DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*(8OG)P*DAP*DGP*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DCP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), ... (4 entities in total)
• Functional Keywords: alka, 8oxoguanine, dna repair, host-guest complex, dna structure, dna damage, hydrolase, hydrolase-dna complex, hydrolase/dna
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 8
• Total formula weight: 140384.54

Authors

Bowman, B.R.,Lee, S.,Wang, S.,Verdine, G.L. (deposition date: 2008-04-19, release date: 2008-09-02, Last modification date: 2024-02-21)

• Primary citation: Bowman, B.R.,Lee, S.,Wang, S.,Verdine, G.L.; Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.; Structure, 16:1166-1174, 2008; PubMed: 18682218; DOI: 10.1016/j.str.2008.04.012

Experimental method

X-RAY DIFFRACTION (2.5 Å)