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PDB: 312 件

6E3R
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Structure of human DNA polymerase beta complexed with 8OA as the template base in a 1-nucleotide gapped DNA
分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
著者Koag, M.-C, Lee, S.
登録日2018-07-14
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases.
J. Am. Chem. Soc., 141, 2019
6E3V
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Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable TTP
分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Koag, M.-C, Lee, S.
登録日2018-07-15
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases.
J. Am. Chem. Soc., 141, 2019
6E3W
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BU of 6e3w by Molmil
Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Koag, M.-C, Lee, S.
登録日2018-07-15
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases.
J. Am. Chem. Soc., 141, 2019
6E3X
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BU of 6e3x by Molmil
Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable ATP
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Koag, M.-C, Lee, S.
登録日2018-07-15
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable ATP
To Be Published
3C9D
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Crystal structure of Vps75
分子名称: Vacuolar protein sorting-associated protein 75
著者Berndsen, C.E, Tsubota, T, Lindner, S.E, Lee, S, Holton, J.M, Kaufman, P.D, Keck, J.L, Denu, J.M.
登録日2008-02-15
公開日2008-08-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75
Nat.Struct.Mol.Biol., 15, 2008
6EQL
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Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant complexed with manganese and UDP
分子名称: 1,2-ETHANEDIOL, Glycogenin-1, MANGANESE (II) ION, ...
著者Bailey, H.J, Kopec, J, Bilyard, M.K, Bezerra, G.A, Seo Lee, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Davis, B.G, Yue, W.W.
登録日2017-10-13
公開日2017-12-20
最終更新日2018-11-14
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis.
Nature, 563, 2018
6EQJ
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Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant, apo form
分子名称: 1,2-ETHANEDIOL, Glycogenin-1
著者Bailey, H.J, Kopec, J, Bilyard, M.K, Bezerra, G.A, Seo Lee, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Davis, B.G, Yue, W.W.
登録日2017-10-13
公開日2017-12-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis.
Nature, 563, 2018
2AF9
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Crystal Structure analysis of GM2-Activator protein complexed with phosphatidylcholine
分子名称: Ganglioside GM2 activator, ISOPROPYL ALCOHOL, LAURIC ACID, ...
著者Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F.
登録日2005-07-25
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AG2
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Crystal Structure Analysis of GM2-activator protein complexed with Phosphatidylcholine
分子名称: (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, 2-(((R)-2,3-DIHYDROXYPROPYL)PHOSPHORYLOXY)-N,N,N-TRIMETHYLETHANAMINIUM, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F.
登録日2005-07-26
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
7LCD
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BU of 7lcd by Molmil
Crystal structure of human polymerase eta complexed with syn N7-acetophenoneguanine
分子名称: DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(*CP*AP*T*(T0P)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA polymerase eta
著者Jung, H, Lee, S.
登録日2021-01-10
公開日2022-02-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structure of human polymerase eta complexed with syn N7-acetophenoneguanine
To Be Published
6U2O
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Structure of human DNA polymerase beta misinserting dAMPNPP opposite the 5'G of the cisplatin Pt-GG intrastrand crosslink
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ...
著者Ouzon-Shubeita, H, Vilas, C.K, Lee, S.
登録日2019-08-20
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of the Mutagenic Bypass of the Major Cisplatin-DNA Lesion by Human DNA Polymerase Beta Reveal Insights into Cisplatin-Induced Mutagenesis
To Be Published
6U6B
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BU of 6u6b by Molmil
Structure of human DNA polymerase beta misinserting dAMPNPP opposite the 5'G of the cisplatin Pt-GG intrastrand crosslink with Manganese in the active site
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ...
著者Ouzon-Shubeita, H, Vilas, C.K, Lee, S.
登録日2019-08-29
公開日2020-09-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.108 Å)
主引用文献Structural insights into the promutagenic bypass of the major cisplatin-induced DNA lesion.
Biochem.J., 477, 2020
6LT4
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BU of 6lt4 by Molmil
AAA+ ATPase, ClpL from Streptococcus pneumoniae: ATPrS-bound
分子名称: ATP-dependent Clp protease, ATP-binding subunit, MAGNESIUM ION, ...
著者Kim, G, Lee, S.G, Han, S, Jung, J, Jeong, H.S, Hyun, J.K, Rhee, D.K, Kim, H.M, Lee, S.
登録日2020-01-21
公開日2021-01-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献ClpL is a functionally active tetradecameric AAA+ chaperone, distinct from hexameric/dodecameric ones.
Faseb J., 34, 2020
6LSY
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BU of 6lsy by Molmil
AAA+ ATPase, ClpL from Streptococcus pneumoniae - ATP bound
分子名称: ATP-dependent Clp protease, ATP-binding subunit
著者Kim, G, Lee, S.G, Han, S, Jung, J, Jeong, H.S, Hyun, J.K, Rhee, D.K, Kim, H.M, Lee, S.
登録日2020-01-20
公開日2021-01-27
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (6.33 Å)
主引用文献ClpL is a functionally active tetradecameric AAA+ chaperone, distinct from hexameric/dodecameric ones.
Faseb J., 34, 2020
4MFA
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BU of 4mfa by Molmil
Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template O6MG and incoming TTP
分子名称: DNA polymerase beta, MAGNESIUM ION, PHOSPHATE ION, ...
著者Koag, M.C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-08-27
公開日2014-08-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structures of human DNA polymerase beta inserting bases opposite templating O6MG
To be Published
2SNW
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BU of 2snw by Molmil
SINDBIS VIRUS CAPSID PROTEIN, TYPE3 CRYSTAL FORM
分子名称: COAT PROTEIN C
著者Choi, H.-K, Lee, S, Zhang, Y.-P, Mckinney, B.R, Wengler, G, Rossmann, M.G, Kuhn, R.J.
登録日1998-02-17
公開日1998-04-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis.
J.Mol.Biol., 262, 1996
8GW7
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BU of 8gw7 by Molmil
AtSLAC1 6D mutant in open state
分子名称: CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment)
著者Lee, Y, Lee, S.
登録日2022-09-16
公開日2023-11-15
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model.
Nat Commun, 14, 2023
8GW6
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AtSLAC1 6D mutant in closed state
分子名称: CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment)
著者Lee, Y, Lee, S.
登録日2022-09-16
公開日2023-11-15
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model.
Nat Commun, 14, 2023
7C11
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BU of 7c11 by Molmil
Formate--tetrahydrofolate ligase from Methylobacterium extorquens CM4 strain
分子名称: ACETATE ION, CITRATE ANION, Formate-tetrahydrofolate ligase, ...
著者Kim, K.-J, Kim, S, Seo, H, Lee, S.
登録日2020-05-02
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.815 Å)
主引用文献Biochemical properties and crystal structure of formate-tetrahydrofolate ligase from Methylobacterium extorquens CM4.
Biochem.Biophys.Res.Commun., 528, 2020
7N1J
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BU of 7n1j by Molmil
Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder
分子名称: Binder, Fibroblast growth factor receptor 4
著者Park, J.S, Lee, S.
登録日2021-05-27
公開日2022-04-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7N1K
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Crystal structure of a de novo-designed mini-protein targeting FGFR
分子名称: Binder
著者Park, J.S, Lee, S.
登録日2021-05-27
公開日2022-04-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7X1K
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BU of 7x1k by Molmil
Crystal structure of the flagellar expression regulator DegU from Listeria monocytogenes
分子名称: Chemotaxis protein CheY
著者Oh, H.B, Lee, S, Yoon, S.I.
登録日2022-02-24
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structural and biochemical analyses of the flagellar expression regulator DegU from Listeria monocytogenes.
Sci Rep, 12, 2022
6VJW
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BU of 6vjw by Molmil
Crystal structure of WT hMBD4 complexed with T:G mismatch DNA
分子名称: DNA (5'-D(*CP*CP*AP*GP*CP*GP*(ORP)P*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*CP*GP*CP*GP*CP*TP*GP*G)-3'), Methyl-CpG-binding domain protein 4
著者Jung, H, Lee, S.
登録日2020-01-17
公開日2021-01-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Catalytic mechanism of the mismatch-specific DNA glycosylase methyl-CpG-binding domain 4.
Biochem.J., 477, 2020
6LHW
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Structure of N-terminal and C-terminal domains of FANCA
分子名称: Fanconi anemia complementation group A
著者Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y.
登録日2019-12-10
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.84 Å)
主引用文献Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex.
Nucleic Acids Res., 48, 2020
6LHV
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BU of 6lhv by Molmil
Structure of FANCA and FANCG Complex
分子名称: Fanconi anemia complementation group A, Fanconi anemia complementation group G
著者Jeong, E, Lee, S, Shin, J, Kim, Y, Scharer, O, Kim, Y, Kim, H, Cho, Y.
登録日2019-12-10
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.59 Å)
主引用文献Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex.
Nucleic Acids Res., 48, 2020

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件を2024-10-30に公開中

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