6VJW

Crystal structure of WT hMBD4 complexed with T:G mismatch DNA

Summary for 6VJW

• Entry DOI: 10.2210/pdb6vjw/pdb
• Descriptor: Methyl-CpG-binding domain protein 4, DNA (5'-D(*CP*CP*AP*GP*CP*GP*(ORP)P*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*CP*GP*CP*GP*CP*TP*GP*G)-3'), ... (4 entities in total)
• Functional Keywords: mbd4, t:g mismatch, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 23847.69

Authors

Jung, H.,Lee, S. (deposition date: 2020-01-17, release date: 2021-01-27, Last modification date: 2023-10-11)

• Primary citation: Ouzon-Shubeita, H.,Jung, H.,Lee, M.H.,Koag, M.C.,Lee, S.; Catalytic mechanism of the mismatch-specific DNA glycosylase methyl-CpG-binding domain 4.; Biochem.J., 477:1601-1612, 2020; PubMed: 32297632; DOI: 10.1042/BCJ20200125

Experimental method

X-RAY DIFFRACTION (2.02 Å)