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6VJW

Crystal structure of WT hMBD4 complexed with T:G mismatch DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Methyl-CpG-binding domain protein 4polymer13816612.01UniProt (O95243)Homo sapiens (Human)Methyl-CpG-binding endonuclease 1,Methyl-CpG-binding protein MBD4,Mismatch-specific DNA N-glycosylase
2B
(C)
DNA (5'-D(*CP*CP*AP*GP*CP*GP*(ORP)P*GP*CP*AP*GP*C)-3')polymer123540.31Homo sapiens
3C
(D)
DNA (5'-D(*GP*CP*TP*GP*CP*GP*CP*GP*CP*TP*GP*G)-3')polymer123695.41Homo sapiens
4D, E, F
(A, C, D)
waterwater18.046Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight23847.7
All*Total formula weight23847.7
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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