6E3R

Structure of human DNA polymerase beta complexed with 8OA as the template base in a 1-nucleotide gapped DNA

Summary for 6E3R

• Entry DOI: 10.2210/pdb6e3r/pdb
• Related: 4XK5 4XK6 4XK7
• Descriptor: DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... (6 entities in total)
• Functional Keywords: dna polymerase, transferase-dna complex, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 47752.86

Authors

Koag, M.-C.,Lee, S. (deposition date: 2018-07-14, release date: 2019-04-03, Last modification date: 2023-10-11)

• Primary citation: Koag, M.C.,Jung, H.,Lee, S.; Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases.; J. Am. Chem. Soc., 141:4584-4596, 2019; PubMed: 30817143; DOI: 10.1021/jacs.8b08551

Experimental method

X-RAY DIFFRACTION (2.26 Å)