Structure of human DNA polymerase beta complexed with 8OA as the template base in a 1-nucleotide gapped DNA

Summary for 6E3R

Related4XK5 4XK6 4XK7
DescriptorDNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... (6 entities in total)
Functional Keywordsdna polymerase, transferase-dna complex, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total molecular weight47752.86
Koag, M.-C.,Lee, S. (deposition date: 2018-07-14, release date: 2019-04-03, Last modification date: 2019-12-18)
Primary citation
Koag, M.C.,Jung, H.,Lee, S.
Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases.
J. Am. Chem. Soc., 141:4584-4596, 2019
PubMed: 30817143 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.8b08551
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.27060 1.8% 4.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28