2ETM
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5CY3
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1LA4
| Solution Structure of SGTx1 | Descriptor: | SGTx1 | Authors: | Lee, C.W, Roh, S.H, Kim, S, Endoh, H, Kodera, Y, Maeda, T, Swartz, K.J, Kim, J.I. | Deposit date: | 2002-03-28 | Release date: | 2003-11-11 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution Structure and Functional Characterization of SGTx1, a Modifier of Kv2.1 Channel Gating Biochemistry, 43, 2004
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5YX3
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5YX4
| Isoliquiritigenin-complexed Chalcone isomerase (S189A) from the Antarctic vascular plant Deschampsia Antarctica (DaCHI1) | Descriptor: | 2',4,4'-TRIHYDROXYCHALCONE, Chalcone-flavonone isomerase family protein | Authors: | Lee, C.W, Park, S, Lee, J.H. | Deposit date: | 2017-12-01 | Release date: | 2018-02-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure and enzymatic properties of chalcone isomerase from the Antarctic vascular plant Deschampsia antarctica Desv. PLoS ONE, 13, 2018
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1AYC
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1AYA
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5Z1X
| Crystal Structure of Laccase from Cerrena sp. RSD1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | Authors: | Lee, C.C, Wu, M.H, Ho, T.H, Wang, A.H.J. | Deposit date: | 2017-12-28 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Kinetic analysis and structural studies of a high-efficiency laccase fromCerrenasp. RSD1. FEBS Open Bio, 8, 2018
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1AQC
| X11 PTB DOMAIN-10MER PEPTIDE COMPLEX | Descriptor: | PEPTIDE, X11 | Authors: | Lee, C.-H, Zhang, Z, Kuriyan, J. | Deposit date: | 1997-07-28 | Release date: | 1997-12-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain. EMBO J., 16, 1997
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1AYD
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1AYB
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8WZX
| Cryo-EM structure of the hamster prion 23-144 fibril at pH 3.7 | Descriptor: | Major prion protein | Authors: | Lee, C.-H, Saw, J.-E, Chen, E, Wang, C.-H, Chen, R. | Deposit date: | 2023-11-02 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | The Positively Charged Cluster in the N-terminal Disordered Region may Affect Prion Protein Misfolding: Cryo-EM Structure of Hamster PrP(23-144) Fibrils. J.Mol.Biol., 436, 2024
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8D6Z
| Crystal structure of SARS-CoV-2 spike stem fusion peptide in complex with neutralizing antibody COV91-27 | Descriptor: | Neutralizing antibody COV91-27 heavy chain, Neutralizing antibody COV91-27 light chain, Spike protein S2 fusion peptide | Authors: | Lee, C.C.D, Lin, T.H, Yuan, M, Wilson, I.A. | Deposit date: | 2022-06-06 | Release date: | 2022-07-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Broadly neutralizing antibodies target the coronavirus fusion peptide. Science, 377, 2022
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8DTR
| Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody COV30-14 | Descriptor: | COV30-14 heavy chain, COV30-14 light chain, Spike protein S2' stem helix peptide | Authors: | Lee, C.C.D, Lin, T.H, Wilson, I.A. | Deposit date: | 2022-07-26 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses. Cell Host Microbe, 31, 2023
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8DTT
| Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody COV93-03 | Descriptor: | COV93-03 heavy chain, COV93-03 light chain, Spike protein S2' stem helix peptide | Authors: | Lee, C.C.D, Lin, T.H, Wilson, I.A. | Deposit date: | 2022-07-26 | Release date: | 2022-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses. Cell Host Microbe, 31, 2023
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4RX8
| SYK Catalytic Domain Complexed with a Potent Triazine Inhibitor2 | Descriptor: | 3-{[(1R,2S)-2-aminocyclohexyl]amino}-5-(1H-indol-7-ylamino)-1,2,4-triazine-6-carboxamide, GLYCEROL, Tyrosine-protein kinase SYK | Authors: | Lee, C.C. | Deposit date: | 2014-12-09 | Release date: | 2015-03-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Discovery and profiling of a selective and efficacious syk inhibitor. J.Med.Chem., 58, 2015
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4RX7
| SYK Catalytic Domain Complexed with a Potent Triazine Inhibitor | Descriptor: | 3-{[(1R,2S)-2-aminocyclohexyl]amino}-5-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}-1,2,4-triazine-6-carboxamide, FORMIC ACID, GLYCEROL, ... | Authors: | Lee, C.C. | Deposit date: | 2014-12-09 | Release date: | 2015-03-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery and profiling of a selective and efficacious syk inhibitor. J.Med.Chem., 58, 2015
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4RX9
| SYK Catalytic Domain Complexed with a Potent Pyrimidine Inhibitor | Descriptor: | 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide, GLYCEROL, Tyrosine-protein kinase SYK | Authors: | Lee, C.C. | Deposit date: | 2014-12-09 | Release date: | 2015-03-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Discovery and profiling of a selective and efficacious syk inhibitor. J.Med.Chem., 58, 2015
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1N4M
| Structure of Rb tumor suppressor bound to the transactivation domain of E2F-2 | Descriptor: | Retinoblastoma Pocket, Transcription factor E2F2 | Authors: | Lee, C, Chang, J.H, Lee, H.S, Cho, Y. | Deposit date: | 2002-10-31 | Release date: | 2003-01-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor GENES DEV., 16, 2002
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6X27
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4XZW
| Endo-glucanase chimera C10 | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Lee, C.C, Chang, C.J, Ho, T.H.D, Chao, Y.C, Wang, A.H.J. | Deposit date: | 2015-02-05 | Release date: | 2016-02-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Endo-glucanase chimera C10 To Be Published
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6WZV
| Lon protease proteolytic domain | Descriptor: | Lon protease homolog, mitochondrial, N-[(1R)-1-borono-3-methylbutyl]-Nalpha-(pyrazine-2-carbonyl)-D-phenylalaninamide, ... | Authors: | Lee, C.C, Spraggon, G. | Deposit date: | 2020-05-14 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J.Med.Chem., 64, 2021
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6X1M
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4XZB
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1IZ3
| Dimeric structure of FIH (Factor inhibiting HIF) | Descriptor: | FIH, SULFATE ION | Authors: | Lee, C, Kim, S.-J, Jeong, D.-G, Lee, S.M, Ryu, S.-E. | Deposit date: | 2002-09-19 | Release date: | 2003-06-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau. J.Biol.Chem., 278, 2003
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