7STU
 
 | | Crystal structure of sulfatase from Pedobacter yulinensis | | 分子名称: | BROMIDE ION, CALCIUM ION, N-acetylgalactosamine-6-sulfatase, ... | | 著者 | O'Malley, A, Schlachter, C.R, Grimes, L.L, Tomashek, J.J, Lee, A.L, Chruszcz, M. | | 登録日 | 2021-11-15 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Purification, Characterization, and Structural Studies of a Sulfatase from Pedobacter yulinensis .
Molecules, 27, 2021
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7STV
 | | Crystal structure of sulfatase from Pedobacter yulinensis | | 分子名称: | CALCIUM ION, CHLORIDE ION, CITRIC ACID, ... | | 著者 | O'Malley, A, Schlachter, C.R, Grimes, L.L, Tomashek, J.J, Lee, A.L, Chruszcz, M. | | 登録日 | 2021-11-15 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Purification, Characterization, and Structural Studies of a Sulfatase from Pedobacter yulinensis .
Molecules, 27, 2021
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2A0L
 | | Crystal structure of KvAP-33H1 Fv complex | | 分子名称: | 33H1 Fv fragment, POTASSIUM ION, Voltage-gated potassium channel | | 著者 | Lee, S.Y, Lee, A, Chen, J, Mackinnon, R. | | 登録日 | 2005-06-16 | | 公開日 | 2005-11-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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1LNQ
 | | CRYSTAL STRUCTURE OF MTHK AT 3.3 A | | 分子名称: | CALCIUM ION, POTASSIUM CHANNEL RELATED PROTEIN | | 著者 | Jiang, Y, Lee, A, Chen, J, Cadene, M, Chait, B.T, Mackinnon, R. | | 登録日 | 2002-05-03 | | 公開日 | 2002-06-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | CRYSTAL STRUCTURE AND MECHANISM OF A CALCIUM-GATED POTASSIUM CHANNEL
Nature, 417, 2002
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1ECM
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3PSA
 | | Classification of a Haemophilus influenzae ABC transporter HI1470/71 through its cognate molybdate periplasmic binding protein MolA (MolA bound to tungstate) | | 分子名称: | TUNGSTATE(VI)ION, protein HI_1472 | | 著者 | Tirado-Lee, L, Lee, A, Rees, D.C, Pinkett, H.W. | | 登録日 | 2010-12-01 | | 公開日 | 2011-11-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Classification of a Haemophilus influenzae ABC Transporter HI1470/71 through Its Cognate Molybdate Periplasmic Binding Protein, MolA.
Structure, 19, 2011
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3PSH
 | | Classification of a Haemophilus influenzae ABC transporter HI1470/71 through its cognate molybdate periplasmic binding protein MolA (MolA bound to Molybdate) | | 分子名称: | MOLYBDATE ION, protein HI_1472 | | 著者 | Tirado-Lee, L, Lee, A, Rees, D.C, Pinkett, H.W. | | 登録日 | 2010-12-01 | | 公開日 | 2011-11-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Classification of a Haemophilus influenzae ABC Transporter HI1470/71 through Its Cognate Molybdate Periplasmic Binding Protein, MolA.
Structure, 19, 2011
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7RRW
 | | Monomeric CRM197 expressed in E. coli | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Diphtheria toxin | | 著者 | Gallagher, D.T, Lees, A. | | 登録日 | 2021-08-10 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Monomeric crystal structure of the vaccine carrier protein CRM 197 and implications for vaccine development.
Acta Crystallogr.,Sect.F, 79, 2023
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1N2Z
 | | 2.0 Angstrom structure of BtuF, the vitamin B12 binding protein of E. coli | | 分子名称: | CADMIUM ION, CHLORIDE ION, CYANOCOBALAMIN, ... | | 著者 | Borths, E.L, Locher, K.P, Lee, A.T, Rees, D.C. | | 登録日 | 2002-10-24 | | 公開日 | 2002-12-18 | | 最終更新日 | 2021-08-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of Escherichia coli BtuF and binding to its cognate ATP binding cassette transporter
Proc.Natl.Acad.Sci.USA, 99, 2002
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5CFL
 | | Crystal structure of anemone STING (Nematostella vectensis) in complex with 3', 3' c-di-GMP, c[G(3', 5')pG(3', 5')p] | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CITRATE ANION, Stimulator of Interferon Genes | | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | | 登録日 | 2015-07-08 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.836 Å) | | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
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1ORQ
 | | X-ray structure of a voltage-dependent potassium channel in complex with an Fab | | 分子名称: | 6E1 Fab heavy chain, 6E1 Fab light chain, CADMIUM ION, ... | | 著者 | Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R. | | 登録日 | 2003-03-14 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | X-ray structure of a voltage-dependent K+ channel
Nature, 423, 2003
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4TXY
 | | Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase, a prokaryotic cGAS homolog | | 分子名称: | Cyclic AMP-GMP synthase, MAGNESIUM ION | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | | 登録日 | 2014-07-07 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.0001 Å) | | 主引用文献 | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
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5CFN
 | | Crystal structure of anemone STING (Nematostella vectensis) in complex with 3',3' c-di-AMP, c[A(3',5')pA(3',5')p] | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Stimulator of Interferon Genes | | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | | 登録日 | 2015-07-08 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
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5CFP
 | | Crystal structure of anemone STING (Nematostella vectensis) 'humanized' F276K in complex with 3', 3' c-di-GMP, c[G(3', 5')pG(3', 5')p]' | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Stimulator of Interferon Genes | | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | | 登録日 | 2015-07-08 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.066 Å) | | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
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5CFO
 | | Crystal structure of anemone STING (Nematostella vectensis) in apo 'rotated' open conformation | | 分子名称: | Stimulator of Interferon Genes | | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | | 登録日 | 2015-07-08 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
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5CFR
 | | Crystal structure of anemone STING (Nematostella vectensis) in apo 'unrotated' closed conformation | | 分子名称: | CALCIUM ION, Stimulator of Interferon Genes | | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | | 登録日 | 2015-07-08 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
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5CFM
 | | Crystal structure of anemone STING (Nematostella vectensis) in complex with 3', 3' cGAMP, c[G(3', 5')pA(3', 5')p] | | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CITRATE ANION, Stimulator of Interferon Genes | | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | | 登録日 | 2015-07-08 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.994 Å) | | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
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5CFQ
 | | Crystal structure of anemone STING (Nematostella vectensis) in complex with 2',3' cGAMP, c[G(2',5')pA(3',5')p] | | 分子名称: | SULFATE ION, Stimulator of Interferon Genes, cGAMP | | 著者 | Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. | | 登録日 | 2015-07-08 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
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1ORS
 | | X-ray structure of the KvAP potassium channel voltage sensor in complex with an Fab | | 分子名称: | 33H1 Fab heavy chain, 33H1 Fab light chain, potassium channel | | 著者 | Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R. | | 登録日 | 2003-03-14 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray structure of a voltage-dependent K+ channel
Nature, 423, 2003
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3DHX
 | | Crystal structure of isolated C2 domain of the methionine uptake transporter | | 分子名称: | IODIDE ION, Methionine import ATP-binding protein metN | | 著者 | Johnson, E, Kaiser, J.T, Lee, A.T, Rees, D.C. | | 登録日 | 2008-06-18 | | 公開日 | 2008-08-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation.
Science, 321, 2008
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3DHW
 | | Crystal structure of methionine importer MetNI | | 分子名称: | D-methionine transport system permease protein metI, Methionine import ATP-binding protein metN | | 著者 | Rees, D.C, Kaiser, J.T, Kadaba, N.S, Johnson, E, Lee, A.T. | | 登録日 | 2008-06-18 | | 公開日 | 2008-08-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation.
Science, 321, 2008
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1L7V
 | | Bacterial ABC Transporter Involved in B12 Uptake | | 分子名称: | CYCLO-TETRAMETAVANADATE, VITAMIN B12 TRANSPORT SYSTEM PERMEASE PROTEIN BTUC, Vitamin B12 transport ATP-binding protein btuD | | 著者 | Locher, K.P, Lee, A.T, Rees, D.C. | | 登録日 | 2002-03-18 | | 公開日 | 2002-05-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism.
Science, 296, 2002
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1SME
 | | PLASMEPSIN II, A HEMOGLOBIN-DEGRADING ENZYME FROM PLASMODIUM FALCIPARUM, IN COMPLEX WITH PEPSTATIN A | | 分子名称: | PLASMEPSIN II, Pepstatin | | 著者 | Silva, A.M, Lee, A.Y, Gulnik, S.V, Goldberg, D.E, Erickson, J.W. | | 登録日 | 1996-06-11 | | 公開日 | 1997-01-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.
Proc.Natl.Acad.Sci.USA, 93, 1996
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4KM5
 | | X-ray crystal structure of human cyclic GMP-AMP synthase (cGAS) | | 分子名称: | Cyclic GMP-AMP synthase, ZINC ION | | 著者 | Kranzusch, P.J, Lee, A.S.Y, Berger, J.M, Doudna, J.A. | | 登録日 | 2013-05-08 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity.
Cell Rep, 3, 2013
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3LNX
 | | Second PDZ domain from human PTP1E | | 分子名称: | IODIDE ION, THIOCYANATE ION, Tyrosine-protein phosphatase non-receptor type 13 | | 著者 | Zhang, J, Chang, A, Ke, H, Phillips Jr, G.N, Lee, A.L, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2010-02-03 | | 公開日 | 2010-02-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.642 Å) | | 主引用文献 | Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.
Biochemistry, 49, 2010
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