6XI2
 
 | | Apo form of POMGNT2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-GLY-ALA-GLY-ALA-ALA-ALA-ALA-ALA-ALA, ... | | Authors: | Halmo, S.M, Yeh, J, Wells, L, Moremen, K.W, Lanzilotta, W.N. | | Deposit date: | 2020-06-19 | | Release date: | 2021-04-21 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | Crystal structures of beta-1,4-N-acetylglucosaminyltransferase 2: structural basis for inherited muscular dystrophies.
Acta Crystallogr D Struct Biol, 77, 2021
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3TFI
 | | DMSP-dependent demethylase from P. ubique - with substrate DMSP | | Descriptor: | 3-(dimethyl-lambda~4~-sulfanyl)propanoic acid, GLYCEROL, GcvT-like Aminomethyltransferase protein, ... | | Authors: | Schuller, D.J, Reisch, C.R, Moran, M.A, Whitman, W.B, Lanzilotta, W.N. | | Deposit date: | 2011-08-15 | | Release date: | 2011-12-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structures of dimethylsulfoniopropionate-dependent demethylase from the marine organism Pelagabacter ubique.
Protein Sci., 21, 2012
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3TFH
 | | DMSP-dependent demethylase from P. ubique - apo | | Descriptor: | GLYCEROL, GcvT-like Aminomethyltransferase protein, SODIUM ION | | Authors: | Schuller, D.J, Reisch, C.R, Moran, M.A, Whitman, W.B, Lanzilotta, W.N. | | Deposit date: | 2011-08-15 | | Release date: | 2011-12-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structures of dimethylsulfoniopropionate-dependent demethylase from the marine organism Pelagabacter ubique.
Protein Sci., 21, 2012
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3TFJ
 | | DMSP-dependent demethylase from P. ubique - with cofactor THF | | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, ACETATE ION, GLYCEROL, ... | | Authors: | Schuller, D.J, Reisch, C.R, Moran, M.A, Whitman, W.B, Lanzilotta, W.N. | | Deposit date: | 2011-08-15 | | Release date: | 2011-12-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structures of dimethylsulfoniopropionate-dependent demethylase from the marine organism Pelagabacter ubique.
Protein Sci., 21, 2012
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6X1O
 | | WOR5 from Pyrococcus furiosus, as crystallized | | Descriptor: | (1R)-1-hydroxybutane-1-sulfonic acid, CHLORIDE ION, Formaldehyde:ferredoxin oxidoreductase wor5, ... | | Authors: | Mathew, L.G, Lanzilotta, W.N. | | Deposit date: | 2020-05-19 | | Release date: | 2021-11-24 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.094 Å) | | Cite: | An unprecedented function for a tungsten-containing oxidoreductase.
J.Biol.Inorg.Chem., 27, 2022
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2QD1
 | | 2.2 Angstrom Structure of the human ferrochelatase variant E343K with substrate bound | | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | Authors: | Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | | Deposit date: | 2007-06-20 | | Release date: | 2007-10-30 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
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2QD4
 | | Wild type human ferrochelatase crystallized with MnCl2 | | Descriptor: | CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | | Deposit date: | 2007-06-20 | | Release date: | 2007-10-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
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2QD5
 | | Structure of wild type human ferrochelatase in complex with a lead-porphyrin compound | | Descriptor: | ACETIC ACID, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Meldock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | | Deposit date: | 2007-06-20 | | Release date: | 2007-10-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
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5FFQ
 | | ChuY: An Anaerobillin Reductase from Escherichia coli O157:H7 | | Descriptor: | 1,4-BUTANEDIOL, PHOSPHATE ION, ShuY-like protein | | Authors: | LaMattina, J.W, Reedy, A.N, Uy, K.G, Lanzilotta, W.N. | | Deposit date: | 2015-12-18 | | Release date: | 2017-01-11 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Radical new paradigm for heme degradation in Escherichia coli O157:H7.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5I2A
 | | 1,2-propanediol Dehydration in Roseburia inulinivorans; Structural Basis for Substrate and Enantiomer Selectivity | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Diol-dehydratase | | Authors: | LaMattina, J.W, Reitzer, P, Kapoor, S, Galzerani, F, Koch, D.J, Gouvea, I.E, Lanzilotta, W.N. | | Deposit date: | 2016-02-08 | | Release date: | 2016-06-01 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | 1,2-Propanediol Dehydration in Roseburia inulinivorans: STRUCTURAL BASIS FOR SUBSTRATE AND ENANTIOMER SELECTIVITY.
J.Biol.Chem., 291, 2016
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4KU1
 | | Role of the hinge and C-gamma-2/C-gamma-3 interface in immunoglobin G1 Fc domain motions: implications for Fc engineering | | Descriptor: | Ig gamma-1 chain C region, TETRAETHYLENE GLYCOL, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Frank, M, Walker, R, Lanzilotta, W.N, Prestegard, J.H, Barb, A.W. | | Deposit date: | 2013-05-21 | | Release date: | 2014-02-19 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Immunoglobulin g1 fc domain motions: implications for fc engineering.
J.Mol.Biol., 426, 2014
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5I2G
 | | 1,2-propanediol Dehydration in Roseburia inulinivorans; Structural Basis for Substrate and Enantiomer Selectivity | | Descriptor: | Diol dehydratase, S-1,2-PROPANEDIOL | | Authors: | LaMattina, J.W, Reitzer, P, Kapoor, S, Galzerani, F, Koch, D.J, Gouvea, I.E, Lanzilotta, W.N. | | Deposit date: | 2016-02-08 | | Release date: | 2016-06-01 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.352 Å) | | Cite: | 1,2-Propanediol Dehydration in Roseburia inulinivorans: STRUCTURAL BASIS FOR SUBSTRATE AND ENANTIOMER SELECTIVITY.
J.Biol.Chem., 291, 2016
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5I3T
 | | Native Structure of the Linalool Dehydratase-Isomerase from Castellaniella defragrans | | Descriptor: | 1,3-BUTANEDIOL, CHLORIDE ION, Linalool dehydratase/isomerase, ... | | Authors: | LaMattina, J.W, Carlock, M, Koch, D.J, Lanzilotta, W.N. | | Deposit date: | 2016-02-11 | | Release date: | 2016-06-01 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Native Structure of the Linalool Dehydratase-Isomerase from Castellaniella defragrans
To Be Published
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2FKZ
 | | Reduced (All Ferrous) form of the Azotobacter vinelandii bacterioferritin | | Descriptor: | Bacterioferritin, FE (II) ION, MAGNESIUM ION, ... | | Authors: | Swartz, L, Kunchinskas, M, Li, H, Poulos, T.L, Lanzilotta, W.N. | | Deposit date: | 2006-01-05 | | Release date: | 2006-04-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Redox-Dependent Structural Changes in the Azotobacter vinelandii Bacterioferritin: New Insights into the Ferroxidase and Iron Transport Mechanism(,).
Biochemistry, 45, 2006
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3HCN
 | | Hg and protoporphyrin bound Human Ferrochelatase | | Descriptor: | BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Medlock, A.E, Dailey, H.A, Lanzilotta, W.N. | | Deposit date: | 2009-05-06 | | Release date: | 2009-11-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
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3HCP
 | | Human ferrochelatase with Mn and deuteroporphyrin bound | | Descriptor: | CHOLIC ACID, FE(III) DEUTEROPORPHYRIN IX, FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Medlock, A.E, Dailey, H.A, Lanzilotta, W.N. | | Deposit date: | 2009-05-06 | | Release date: | 2009-11-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
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3HCO
 | | Human ferrochelatase with Cd and protoporphyrin IX bound | | Descriptor: | BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Medlock, A.E, Dailey, H.A, Lanzilotta, W.N. | | Deposit date: | 2009-05-06 | | Release date: | 2009-11-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
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3HCR
 | | Human Ferrochelatase with deuteroporphyrin and Ni Bound | | Descriptor: | CHLORIDE ION, CHOLIC ACID, FE(III) DEUTEROPORPHYRIN IX, ... | | Authors: | Medlock, A.E, Dailey, H.A, Lanzilotta, W.N. | | Deposit date: | 2009-05-06 | | Release date: | 2009-11-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Product release rather than chelation determines metal specificity for ferrochelatase.
J.Mol.Biol., 393, 2009
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2HRC
 | | 1.7 angstrom structure of human ferrochelatase variant R115L | | Descriptor: | CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Medlock, A, Swartz, L, Dailey, T.A, Dailey, H.A, Lanzilotta, W.N. | | Deposit date: | 2006-07-20 | | Release date: | 2007-03-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Substrate interactions with human ferrochelatase
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2HRE
 | | Structure of human ferrochelatase variant E343K with protoporphyrin IX bound | | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | Authors: | Medlock, A, Swartz, L, Dailey, T.A, Dailey, H.A, Lanzilotta, W.N. | | Deposit date: | 2006-07-20 | | Release date: | 2007-03-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Substrate interactions with human ferrochelatase
Proc.Natl.Acad.Sci.Usa, 104, 2007
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1YCG
 | | X-ray Structures of Moorella thermoacetica FprA. Novel Diiron Site Structure and Mechanistic Insights into a Scavenging Nitric Oxide Reductase | | Descriptor: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, MU-OXO-DIIRON, ... | | Authors: | Silaghi-Dumitrescu, R, Kurtz, D.M, Lanzilotta, W.N. | | Deposit date: | 2004-12-22 | | Release date: | 2005-04-19 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | X-ray crystal structures of Moorella thermoacetica FprA. Novel diiron site structure and mechanistic insights into a scavenging nitric oxide reductase.
Biochemistry, 44, 2005
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1YCH
 | | X-ray Crystal Structures of Moorella thermoacetica FprA. Novel Diiron Site Structure and Mechanistic Insights into a Scavenging Nitric Oxide Reductase | | Descriptor: | FLAVIN MONONUCLEOTIDE, MU-OXO-DIIRON, Nitric oxide reductase, ... | | Authors: | Silaghi-Dumitrescu, R, Kurtz, D.M, Lanzilotta, W.N. | | Deposit date: | 2004-12-22 | | Release date: | 2005-04-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | X-ray crystal structures of Moorella thermoacetica FprA. Novel diiron site structure and mechanistic insights into a scavenging nitric oxide reductase.
Biochemistry, 44, 2005
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1YCF
 | | Oxidized (di-ferric) FprA from Moorella thermoacetica | | Descriptor: | FLAVIN MONONUCLEOTIDE, MU-OXO-DIIRON, Nitric oxide reductase, ... | | Authors: | Silaghi-Dumitrescu, R, Kurtz, D.M, Lanzilotta, W.N. | | Deposit date: | 2004-12-22 | | Release date: | 2005-04-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray crystal structures of Moorella thermoacetica FprA. Novel diiron site structure and mechanistic insights into a scavenging nitric oxide reductase.
Biochemistry, 44, 2005
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1YUX
 | | Mixed valant state of nigerythrin | | Descriptor: | FE (II) ION, FE (III) ION, Nigerythrin | | Authors: | Iyer, R.B, Silaghi-Dumitrescu, R, Kurtz, D.M, Lanzilotta, W.N. | | Deposit date: | 2005-02-14 | | Release date: | 2005-06-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | High-resolution crystal structures of Desulfovibrio vulgaris (Hildenborough) nigerythrin: facile, redox-dependent iron movement, domain interface variability, and peroxidase activity in the rubrerythrins.
J.Biol.Inorg.Chem., 10, 2005
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1YV1
 | | Fully reduced state of nigerythrin (all ferrous) | | Descriptor: | FE (II) ION, Nigerythrin | | Authors: | Iyer, R.B, Silaghi-Dumitrescu, R, Kurtz, D.M, Lanzilotta, W.N. | | Deposit date: | 2005-02-14 | | Release date: | 2005-06-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | High-resolution crystal structures of Desulfovibrio vulgaris (Hildenborough) nigerythrin: facile, redox-dependent iron movement, domain interface variability, and peroxidase activity in the rubrerythrins.
J.Biol.Inorg.Chem., 10, 2005
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