2HRE
Structure of human ferrochelatase variant E343K with protoporphyrin IX bound
Summary for 2HRE
| Entry DOI | 10.2210/pdb2hre/pdb |
| Related | 1HRK 2HRC |
| Descriptor | Ferrochelatase, PROTOPORPHYRIN IX, FE2/S2 (INORGANIC) CLUSTER, ... (5 entities in total) |
| Functional Keywords | heme synthesis, ferrochelatase, protoporphyrin ix, lyase |
| Biological source | Homo sapiens (human) |
| Cellular location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side: P22830 |
| Total number of polymer chains | 4 |
| Total formula weight | 169610.18 |
| Authors | Medlock, A.,Swartz, L.,Dailey, T.A.,Dailey, H.A.,Lanzilotta, W.N. (deposition date: 2006-07-20, release date: 2007-03-13, Last modification date: 2023-11-29) |
| Primary citation | Medlock, A.,Swartz, L.,Dailey, T.A.,Dailey, H.A.,Lanzilotta, W.N. Substrate interactions with human ferrochelatase Proc.Natl.Acad.Sci.Usa, 104:1789-1793, 2007 Cited by PubMed: 17261801DOI: 10.1073/pnas.0606144104 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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