1MX6
 
 | | Structure of p18INK4c (F92N) | | Descriptor: | Cyclin-dependent kinase 6 inhibitor | | Authors: | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiry, W.S. | | Deposit date: | 2002-10-01 | | Release date: | 2002-10-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity
J.Biol.Chem., 277, 2002
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5E3J
 | | The response regulator RstA is a potential drug target for Acinetobacter baumannii | | Descriptor: | Response regulator RstA | | Authors: | Russo, T.A, Manohar, A, Beanan, J.M, Olson, R, MacDonald, U, Graham, J, Umland, T.C. | | Deposit date: | 2015-10-02 | | Release date: | 2016-05-04 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Response Regulator BfmR Is a Potential Drug Target for Acinetobacter baumannii.
Msphere, 1, 2016
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1P65
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1N0D
 | | Stability of cyclic beta-hairpins: Asymmetric contibutions from side chains of hydrogen bonded cross-strand residue pair | | Descriptor: | bhp_VWLH, disulfide cyclized beta-hairpin peptide | | Authors: | Russell, S.J, Blandl, T, Skelton, N.J, Cochran, A.G. | | Deposit date: | 2002-10-11 | | Release date: | 2003-02-04 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Stability of Cyclic Beta-Hairpins: Asymmetric Contributions From Side Chains of Hydrogen Bonded Cross-Strand Residue Pair
J.Am.Chem.Soc., 125, 2003
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4Y0A
 | | Shikimate kinase from Acinetobacter baumannii in complex with shikimate | | Descriptor: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, SULFATE ION, Shikimate kinase | | Authors: | Sutton, K.A, Breen, J, MacDonald, U, Beanan, J.M, Olson, R, Russo, T.A, Schultz, L.W, Umland, T.C. | | Deposit date: | 2015-02-05 | | Release date: | 2015-08-12 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.911 Å) | | Cite: | Structure of shikimate kinase, an in vivo essential metabolic enzyme in the nosocomial pathogen Acinetobacter baumannii, in complex with shikimate.
Acta Crystallogr.,Sect.D, 71, 2015
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1CD3
 | | PROCAPSID OF BACTERIOPHAGE PHIX174 | | Descriptor: | PROTEIN (CAPSID PROTEIN GPF), PROTEIN (SCAFFOLDING PROTEIN GPB), PROTEIN (SCAFFOLDING PROTEIN GPD), ... | | Authors: | Rossmann, M.G, Dokland, T. | | Deposit date: | 1999-03-05 | | Release date: | 1999-04-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The role of scaffolding proteins in the assembly of the small, single-stranded DNA virus phiX174.
J.Mol.Biol., 288, 1999
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1P2X
 | | CRYSTAL STRUCTURE OF THE CALPONIN-HOMOLOGY DOMAIN OF RNG2 FROM SCHIZOSACCHAROMYCES POMBE | | Descriptor: | BROMIDE ION, Ras GTPase-activating-like protein | | Authors: | Wang, C.-H, Balasubramanian, M.K, Dokland, T. | | Deposit date: | 2003-04-16 | | Release date: | 2004-06-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Structure, crystal packing and molecular dynamics of the calponin-homology domain of Schizosaccharomyces pombe Rng2.
Acta Crystallogr.,Sect.D, 60, 2004
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1N0C
 | | Stability of cyclic beta-hairpins: Asymmetric contibutions from side chains of hydrogen bonded cross-strand residue pair | | Descriptor: | bhp_HWLV, disulfide cyclized beta-hairpin peptide | | Authors: | Russel, S.J, Blandl, T, Skelton, N.J, Cochran, A.G. | | Deposit date: | 2002-10-11 | | Release date: | 2003-10-21 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Stability of cyclic beta-hairpins: asymmetric contributions from side chains of
a hydrogen-bonded cross-strand residue pair
J.AM.CHEM.SOC., 125, 2003
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5JJF
 | | Structure of the SRII/HtrII Complex in I212121 space group ("U" shape) - M state | | Descriptor: | EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... | | Authors: | Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Polovinkin, V, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. | | Deposit date: | 2016-04-23 | | Release date: | 2017-02-15 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex.
Sci Rep, 7, 2017
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5JJE
 | | Structure of the SRII/HtrII Complex in I212121 space group ("U" shape) | | Descriptor: | EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... | | Authors: | Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Polovinkin, V, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. | | Deposit date: | 2016-04-23 | | Release date: | 2017-02-15 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex.
Sci Rep, 7, 2017
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6HN4
 | | Leucine-zippered human insulin receptor ectodomain with single bound insulin - "lower" membrane-proximal part | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor,Insulin receptor,General control protein GCN4 | | Authors: | Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. | | Deposit date: | 2018-09-14 | | Release date: | 2018-11-21 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | The signalling conformation of the insulin receptor ectodomain.
Nat Commun, 9, 2018
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6HN5
 | | Leucine-zippered human insulin receptor ectodomain with single bound insulin - "upper" membrane-distal part | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ... | | Authors: | Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. | | Deposit date: | 2018-09-14 | | Release date: | 2018-11-21 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The signalling conformation of the insulin receptor ectodomain.
Nat Commun, 9, 2018
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4XXJ
 | | Crystal Structure of Escherichia coli-Expressed Halobacterium salinarum Bacteriorhodopsin in the Trimeric Form | | Descriptor: | Bacteriorhodopsin, EICOSANE, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate | | Authors: | Bratanov, D, Balandin, T, Round, E, Gushchin, I, Gordeliy, V. | | Deposit date: | 2015-01-30 | | Release date: | 2015-07-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | An Approach to Heterologous Expression of Membrane Proteins. The Case of Bacteriorhodopsin.
Plos One, 10, 2015
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1P5S
 | | STRUCTURE AND FUNCTION OF THE CALPONIN-HOMOLOGY DOMAIN OF AN IQGAP PROTEIN FROM SCHIZOSACCHAROMYCES POMBE | | Descriptor: | MERCURY (II) ION, Ras GTPase-activating-like protein rng2 | | Authors: | Wang, C.H, Balasubramanian, M.K, Dokland, T. | | Deposit date: | 2003-04-28 | | Release date: | 2004-05-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Structure, crystal packing and molecular dynamics of the calponin-homology domain of Schizosaccharomyces pombe Rng2.
Acta Crystallogr.,Sect.D, 60, 2004
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2Z23
 | | Crystal structure of Y.pestis oligo peptide binding protein OppA with tri-lysine ligand | | Descriptor: | Periplasmic oligopeptide-binding protein, peptide (LYS)(LYS)(LYS) | | Authors: | Tanabe, M, Bertland, T, Mirza, O, Byrne, B, Brown, K.A. | | Deposit date: | 2007-05-17 | | Release date: | 2007-10-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of OppA and PstS from Yersinia pestis indicate variability of interactions with transmembrane domains.
Acta Crystallogr.,Sect.D, 63, 2007
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4C4X
 | | Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with C9 | | Descriptor: | 3-(3,4-dichlorophenyl)-1,1-dimethyl-urea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | | Authors: | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | | Deposit date: | 2013-09-09 | | Release date: | 2014-10-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4C4Z
 | | Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with A8 | | Descriptor: | 1-ethyl-3-naphthalen-1-ylurea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | | Authors: | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | | Deposit date: | 2013-09-09 | | Release date: | 2014-10-01 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4C4Y
 | | Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with A4 | | Descriptor: | 1-(3-chlorophenyl)-3-(2-methoxyethyl)urea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | | Authors: | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | | Deposit date: | 2013-09-09 | | Release date: | 2014-10-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
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1K0Z
 | | Crystal Structure of the PvuII endonuclease with Pr3+ and SO4 ions bound in the active site at 2.05A. | | Descriptor: | PRASEODYMIUM ION, SULFATE ION, Type II restriction enzyme PvuII | | Authors: | Spyridaki, A, Athanasiadis, A, Matzen, C, Lanio, T, Jeltsch, A, Simoncsits, A, Scheuring-Vanamee, E, Kokkinidis, M, Pingoud, A. | | Deposit date: | 2001-09-21 | | Release date: | 2003-06-17 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: |
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2Z22
 | | Crystal structure of phosphate preplasmic binding protein psts from yersinia pestis | | Descriptor: | PHOSPHATE ION, Periplasmic phosphate-binding protein | | Authors: | Tanabe, M, Byrne, B, Brown, K.A, Mirza, O, Bertland, T. | | Deposit date: | 2007-05-17 | | Release date: | 2007-10-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of OppA and PstS from Yersinia pestis indicate variability of interactions with transmembrane domains.
Acta Crystallogr.,Sect.D, 63, 2007
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4E4V
 | | The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Importin subunit alpha-2 | | Authors: | Hang, P.C, Miknis, Z.M, Franke, W.A, Umland, T.C, Schultz, L.W. | | Deposit date: | 2012-03-13 | | Release date: | 2013-05-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.5283 Å) | | Cite: | The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution.
To be Published
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3BU8
 | | Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex | | Descriptor: | TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2 | | Authors: | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | | Deposit date: | 2008-01-02 | | Release date: | 2008-02-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
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3C7L
 | | Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation | | Descriptor: | Regulator of G-protein signaling 16 | | Authors: | Slep, K.C, Kercher, M.A, Wieland, T, Chen, C, Simon, M.I, Sigler, P.B. | | Deposit date: | 2008-02-07 | | Release date: | 2008-05-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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4OV0
 | | Structure of Bacteriorhdopsin Transferred from Amphipol A8-35 to a Lipidic Mesophase | | Descriptor: | Bacteriorhodopsin, RETINAL | | Authors: | Polovinkin, V, Gushchin, I, Sintsov, M, Round, E, Balandin, T, Chervakov, P, Schevchenko, V, Utrobin, P, Popov, A, Borshchevskiy, V, Mishin, A, Kuklin, A, Willbold, D, Popot, J.L, Gordeliy, V. | | Deposit date: | 2014-02-19 | | Release date: | 2014-10-01 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | High-resolution structure of a membrane protein transferred from amphipol to a lipidic mesophase.
J.Membr.Biol., 247, 2014
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1EAP
 | | CRYSTAL STRUCTURE OF A CATALYTIC ANTIBODY WITH A SERINE PROTEASE ACTIVE SITE | | Descriptor: | IGG2B-KAPPA 17E8 FAB (HEAVY CHAIN), IGG2B-KAPPA 17E8 FAB (LIGHT CHAIN), PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE | | Authors: | Zhou, G.W, Guo, J, Huang, W, Scanlan, T.S, Fletterick, R.J. | | Deposit date: | 1994-08-10 | | Release date: | 1994-12-20 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of a catalytic antibody with a serine protease active site.
Science, 265, 1994
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