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PDB: 76 件

7ZOP
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Carbohydrate binding domain CBM92-B from a multi-catalytic glucanase-chitinase from Chitinophaga pinensis DSM 2588 in complex with sophorose.
分子名称: Glycoside hydrolase family 18, beta-D-glucopyranose
著者Mazurkewich, S, McKee, L.S, Lu, Z, Branden, G, Larsbrink, J.
登録日2022-04-26
公開日2023-05-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural and biochemical analysis of family 92 carbohydrate-binding modules uncovers multivalent binding to beta-glucans.
Nat Commun, 15, 2024
9AVL
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Structure of human calcium-sensing receptor in complex with Gi3 protein in nanodiscs
分子名称: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-04
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AYF
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Structure of human calcium-sensing receptor in complex with Gi1 (miniGi1) protein in detergent
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-07
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AVG
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Structure of human calcium-sensing receptor in complex with chimeric Gs (miniGis) protein in nanodiscs
分子名称: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-02
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9AXF
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Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-03-06
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
9ASB
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Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in nanodiscs
分子名称: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R.
登録日2024-02-24
公開日2024-04-17
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Promiscuous G-protein activation by the calcium-sensing receptor.
Nature, 629, 2024
5KZO
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Notch1 transmembrane and associated juxtamembrane segment
分子名称: Neurogenic locus notch homolog protein 1
著者Deatherage, C.L, Lu, Z, Kroncke, B.
登録日2016-07-25
公開日2017-05-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and biochemical differences between the Notch and the amyloid precursor protein transmembrane domains.
Sci Adv, 3, 2017
7ZOH
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Carbohydrate binding domain CBM92-B from a multi-catalytic glucanase-chitinase from Chitinophaga pinensis DSM 2588
分子名称: Glycoside hydrolase family 18
著者Mazurkewich, S, McKee, L.S, Lu, Z, Branden, G, Larsbrink, J.
登録日2022-04-25
公開日2023-05-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Structural and biochemical analysis of family 92 carbohydrate-binding modules uncovers multivalent binding to beta-glucans.
Nat Commun, 15, 2024
3K6N
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Crystal structure of the S225E mutant Kir3.1 cytoplasmic pore domain
分子名称: G protein-activated inward rectifier potassium channel 1, SODIUM ION
著者Xu, Y, Shin, H.G, Szep, S, Lu, Z.
登録日2009-10-09
公開日2009-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Physical determinants of strong voltage sensitivity of K(+) channel block.
Nat.Struct.Mol.Biol., 16, 2009
1XG3
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Crystal structure of the C123S 2-methylisocitrate lyase mutant from Escherichia coli in complex with the reaction product, Mg(II)-pyruvate and succinate
分子名称: MAGNESIUM ION, PYRUVIC ACID, Probable methylisocitrate lyase, ...
著者Liu, S, Lu, Z, Han, Y, Melamud, E, Dunaway-Mariano, D, Herzberg, O.
登録日2004-09-16
公開日2005-03-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of 2-Methylisocitrate Lyase in Complex with Product and with Isocitrate Inhibitor Provide Insight into Lyase Substrate Specificity, Catalysis and Evolution
Biochemistry, 44, 2005
1XG4
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Crystal Structure of the C123S 2-Methylisocitrate Lyase Mutant from Escherichia coli in complex with the inhibitor isocitrate
分子名称: ISOCITRIC ACID, MAGNESIUM ION, Probable methylisocitrate lyase
著者Liu, S, Lu, Z, Han, Y, Melamud, E, Dunaway-Mariano, D, Herzberg, O.
登録日2004-09-16
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structures of 2-Methylisocitrate Lyase in Complex with Product and with Isocitrate Inhibitor Provide Insight into Lyase Substrate Specificity, Catalysis and Evolution
Biochemistry, 44, 2005
3GBS
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BU of 3gbs by Molmil
Crystal structure of Aspergillus oryzae cutinase
分子名称: Cutinase 1
著者Gosser, Y, Lu, Z, Alemu, G, Li, H, Kong, X, Liu, Z, Montclare, J.
登録日2009-02-20
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and functional studies of Aspergillus oryzae cutinase: enhanced thermostability and hydrolytic activity of synthetic ester and polyester degradation.
J.Am.Chem.Soc., 131, 2009
1EZ8
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STRUCTURE OF S. NUCLEASE STABILIZING MUTANT T33V
分子名称: STAPHYLOCOCCAL NUCLEASE
著者Chen, J, Lu, Z, Sakon, J, Stites, W.E.
登録日2000-05-10
公開日2000-10-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Increasing the thermostability of staphylococcal nuclease: implications for the origin of protein thermostability.
J.Mol.Biol., 303, 2000
1EZ6
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STRUCTURE OF S. NUCLEASE STABILIZING SEXTUPLE MUTANT T33V/T41I/S59A/P117G/H124L/S128A
分子名称: STAPHYLOCOCCAL NUCLEASE
著者Chen, J, Lu, Z, Sakon, J, Stites, W.E.
登録日2000-05-10
公開日2000-10-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Increasing the thermostability of staphylococcal nuclease: implications for the origin of protein thermostability.
J.Mol.Biol., 303, 2000
5GJB
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Zika virus NS3 helicase in complex with ssRNA
分子名称: NS3 helicase, RNA (5'-R(*AP*GP*AP*UP*CP*AP*A)-3')
著者Tian, H.L, Ji, X.Y, Yang, X.Y, Zhang, Z.X, Lu, Z.K, Yang, K.L, Chen, C, Zhao, Q, Chi, H, Mu, Z.Y, Xie, W, Wang, Z.F, Lou, H.Q, Yang, H.T, Rao, Z.H.
登録日2016-06-28
公開日2016-07-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Structural basis of Zika virus helicase in recognizing its substrates
Protein Cell, 7, 2016
5GJC
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Zika virus NS3 helicase in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, NS3 helicase
著者Tian, H.L, Ji, X.Y, Yang, X.Y, Zhang, Z.X, Lu, Z.K, Yang, K.L, Chen, C, Zhao, Q, Chi, H, Mu, Z.Y, Xie, W, Wang, Z.F, Lou, H.Q, Yang, H.T, Rao, Z.H.
登録日2016-06-28
公開日2016-07-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Structural basis of Zika virus helicase in recognizing its substrates
Protein Cell, 7, 2016
1IHZ
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Structure of S. nuclease mutant quintuple mutant V23L/V66L/I72L/I92L/V99L
分子名称: STAPHYLOCOCCAL NUCLEASE
著者Chen, J, Lu, Z, Sakon, J, Stites, W.E.
登録日2001-04-20
公開日2003-06-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Proteins with simplified hydrophobic cores compared to other packing mutants.
Biophys.Chem., 110, 2004
1II3
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Structure of S. nuclease quintuple mutant V23I/V66L/I72L/I92L/V99L
分子名称: STAPHYLOCOCCAL NUCLEASE
著者Chen, J, Lu, Z, Sakon, J, Stites, W.E.
登録日2001-04-20
公開日2003-06-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Proteins with simplified hydrophobic cores compared to other packing mutants.
Biophys.Chem., 110, 2004
8XIZ
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Crystal structure of an epoxide hydrolase mutant A250IC/L344V from Aspergillus usamii E001 at 2.17 Angstroms resolution
分子名称: Microsomal epoxide hyddrolase
著者Hu, B.C, Lu, Z.Y, Tang, C.D, Hu, D.
登録日2023-12-20
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.175 Å)
主引用文献Directed evolution of an epoxide hydrolase and its structural mechanism for the enantioselectivity improvement toward chiral ortho-fluorostyrene oxide
To Be Published
1M1B
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Crystal Structure of Phosphoenolpyruvate Mutase Complexed with Sulfopyruvate
分子名称: MAGNESIUM ION, PHOSPHOENOLPYRUVATE PHOSPHOMUTASE, SULFOPYRUVATE
著者Liu, S, Lu, Z, Jia, Y, Dunaway-Mariano, D, Herzberg, O.
登録日2002-06-18
公開日2002-08-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Dissociative phosphoryl transfer in PEP mutase catalysis: structure of the enzyme/sulfopyruvate complex and kinetic properties of mutants.
Biochemistry, 41, 2002
3S0M
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A Structural Element that Modulates Proton-Coupled Electron Transfer in Oxalate Decarboxylase
分子名称: 1,2-ETHANEDIOL, CARBONATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Saylor, B.T, Reinhardt, L.A, Lu, Z, Shukla, M.S, Cleland, W.W, Allen, K.N, Richards, N.G.J.
登録日2011-05-13
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献A structural element that facilitates proton-coupled electron transfer in oxalate decarboxylase.
Biochemistry, 51, 2012
4ZLK
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Crystal structure of mouse myosin-5a in complex with calcium-bound calmodulin
分子名称: CALCIUM ION, Calmodulin, Unconventional myosin-Va
著者Shen, M, Zhang, N, Zheng, S, Zhang, W.-B, Zhang, H.-M, Lu, Z, Su, Q.P, Sun, Y, Ye, K, Li, X.-D.
登録日2015-05-01
公開日2016-05-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Structural basis for calcium regulation of myosin 5 motor function
To Be Published
2L0K
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NMR solution structure of a transcription factor SpoIIID in complex with DNA
分子名称: Stage III sporulation protein D
著者Chen, B, Himes, P, Lu, Z, Liu, A, Yan, H, Kroos, L.
登録日2010-07-08
公開日2011-08-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Novel Mode of DNA Binding by Bacterial Transcription Factor SpoIIID
To be Published
5WIE
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Crystal structure of a Kv1.2-2.1 chimera K+ channel V406W mutant in an inactivated state
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ...
著者Pau, V, Zhou, Y, Ramu, Y, Xu, Y, Lu, Z.
登録日2017-07-19
公開日2017-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of an inactivated mutant mammalian voltage-gated K(+) channel.
Nat. Struct. Mol. Biol., 24, 2017
1LIR
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LQ2 FROM LEIURUS QUINQUESTRIATUS, NMR, 22 STRUCTURES
分子名称: LQ2
著者Renisio, J.G, Lu, Z, Blanc, E, Jin, W, Lewis, J.H, Bornet, O, Darbon, H.
登録日1998-04-02
公開日1998-06-17
最終更新日2019-12-25
実験手法SOLUTION NMR
主引用文献Solution structure of potassium channel-inhibiting scorpion toxin Lq2.
Proteins, 34, 1999

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