5A9G
 
 | | Manganese Superoxide Dismutase from Sphingobacterium sp. T2 | | 分子名称: | MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE | | 著者 | Rashid, G.M.M, Taylor, C.R, Liu, Y, Zhang, X, Rea, D, Fulop, V, Bugg, T.D.H. | | 登録日 | 2015-07-21 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Identification of Manganese Superoxide Dismutase from Sphingobacterium Sp. T2 as a Novel Bacterial Enzyme for Lignin Oxidation.
Acs Chem.Biol., 10, 2015
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8F41
 | | 3-methylcrotonyl-CoA carboxylase in filament, alpha-subunit centered | | 分子名称: | 3-methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit, ... | | 著者 | Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H. | | 登録日 | 2022-11-10 | | 公開日 | 2023-01-11 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.
Structure, 31, 2023
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5JZC
 | | helical filament | | 分子名称: | DNA repair protein RAD51 homolog 1 | | 著者 | Short, J, Liu, Y. | | 登録日 | 2016-05-16 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.
Nucleic Acids Res., 44, 2016
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2H40
 | | Crystal structure of the catalytic domain of unliganded PDE5 | | 分子名称: | MAGNESIUM ION, ZINC ION, cGMP-specific 3',5'-cyclic phosphodiesterase | | 著者 | Wang, H, Liu, Y, Huai, Q, Cai, J, Zoraghi, R, Francis, S.H, Corbin, J.D, Robinson, H, Xin, Z, Lin, G, Ke, H. | | 登録日 | 2006-05-23 | | 公開日 | 2006-06-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
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5EWU
 | | Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A | | 分子名称: | BENZOIC ACID, MAGNESIUM ION, Magnesium-chelatase subunit ChlH, ... | | 著者 | Chen, Z, Zhang, X, Liu, Y, Jiang, L. | | 登録日 | 2015-11-21 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A
To Be Published
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5DF6
 | | Crystal structure of PTPN11 tandem SH2 domains in complex with a TXNIP peptide | | 分子名称: | Tyrosine-protein phosphatase non-receptor type 11, UNKNOWN ATOM OR ION, txnip | | 著者 | Dong, A, Li, W, Tempel, W, Liu, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2015-08-26 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP.
Biochem.J., 473, 2016
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5EG7
 | | The cap binding site of influenza virus protein PB2 as a drug target | | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, Polymerase basic protein 2 | | 著者 | Severin, C, Rocha de Moura, T, Liu, Y, Li, K, Zheng, X, Luo, M. | | 登録日 | 2015-10-26 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | The cap-binding site of influenza virus protein PB2 as a drug target.
Acta Crystallogr D Struct Biol, 72, 2016
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4H53
 | | Influenza N2-Tyr406Asp neuraminidase in complex with beta-Neu5Ac | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Vavricka, C.J, Liu, Y, Kiyota, H, Sriwilaijaroen, N, Qi, J, Tanaka, K, Wu, Y, Li, Q, Li, Y, Yan, J, Suzuki, Y, Gao, G.F. | | 登録日 | 2012-09-18 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors
Nat Commun, 4, 2013
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5XWF
 | | Crystal structure of chitinase (RmChi1) from Rhizomucor miehei (SP3221/SAD) | | 分子名称: | Fungal chitinase from Rhizomucor miehei (SeMet-substituted proteins) | | 著者 | Jiang, Z.Q, Hu, S.Q, Liu, Y.C, Qin, Z, Yan, Q.J, Yang, S.Q. | | 登録日 | 2017-06-29 | | 公開日 | 2018-07-04 | | 最終更新日 | 2021-08-18 | | 実験手法 | X-RAY DIFFRACTION (2.581 Å) | | 主引用文献 | Crystal structure of a chitinase (RmChiA) from the thermophilic fungus Rhizomucor miehei with a real active site tunnel.
Biochim Biophys Acta Proteins Proteom, 2021
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5EG9
 | | The cap binding site of influenza virus protein PB2 as a drug target | | 分子名称: | Polymerase basic protein 2 | | 著者 | Severin, C, Rocha de Moura, T, Liu, Y, Li, K, Zheng, X, Luo, M. | | 登録日 | 2015-10-26 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The cap-binding site of influenza virus protein PB2 as a drug target.
Acta Crystallogr D Struct Biol, 72, 2016
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5GNY
 | | The structure of WT Bgl6 | | 分子名称: | Beta-glucosidase, beta-D-glucopyranose | | 著者 | Xie, W, Pang, P, Cao, L.C, Liu, Y.H, Wang, Z. | | 登録日 | 2016-07-25 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.105 Å) | | 主引用文献 | Structures of a glucose-tolerant beta-glucosidase provide insights into its mechanism.
J. Struct. Biol., 198, 2017
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4H52
 | | Wild-type influenza N2 neuraminidase covalent complex with 3-fluoro-Neu5Ac | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, CALCIUM ION, ... | | 著者 | Vavricka, C.J, Liu, Y, Kiyota, H, Sriwilaijaroen, N, Qi, J, Tanaka, K, Wu, Y, Li, Q, Li, Y, Yan, J, Suzuki, Y, Gao, G.F. | | 登録日 | 2012-09-18 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | | 主引用文献 | Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors
Nat Commun, 4, 2013
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4LYR
 | | Glycoside Hydrolase Family 5 Mannosidase from Rhizomucor miehei, E301A mutant | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Exo-beta-1,4-mannosidase | | 著者 | Jiang, Z.Q, Zhou, P, Yang, S.Q, Liu, Y, Yan, Q.J. | | 登録日 | 2013-07-31 | | 公開日 | 2014-08-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase.
Acta Crystallogr.,Sect.D, 70, 2014
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4LYQ
 | | Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase from Rhizomucor miehei, E202A mutant | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Exo-beta-1,4-mannosidase, ... | | 著者 | Jiang, Z.Q, Zhou, P, Yang, S.Q, Liu, Y, Yan, Q.J. | | 登録日 | 2013-07-31 | | 公開日 | 2014-08-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase.
Acta Crystallogr.,Sect.D, 70, 2014
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5GNX
 | | The E171Q mutant structure of Bgl6 | | 分子名称: | Beta-glucosidase, GLYCEROL, PROPANOIC ACID, ... | | 著者 | Xie, W, Pang, P, Cao, L.C, Liu, Y.H, Wang, Z. | | 登録日 | 2016-07-25 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of a glucose-tolerant beta-glucosidase provide insights into its mechanism.
J. Struct. Biol., 198, 2017
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7EVP
 | | Cryo-EM structure of the Gp168-beta-clamp complex | | 分子名称: | Beta sliding clamp, Sliding clamp inhibitor | | 著者 | Liu, B, Li, S, Liu, Y, Chen, H, Hu, Z, Wang, Z, Gou, L, Zhang, L, Ma, B, Wang, H, Matthews, S, Wang, Y, Zhang, K. | | 登録日 | 2021-05-21 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Bacteriophage Twort protein Gp168 is a beta-clamp inhibitor by occupying the DNA sliding channel.
Nucleic Acids Res., 49, 2021
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2HWV
 | | Crystal structure of an essential response regulator DNA binding domain, VicRc in Enterococcus faecalis, a member of the YycF subfamily. | | 分子名称: | DNA-binding response regulator VicR, SULFATE ION | | 著者 | Trinh, C.H, Liu, Y, Phillips, S.E.V, Phillips-Jones, M.K. | | 登録日 | 2006-08-02 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the response regulator VicR DNA-binding domain.
Acta Crystallogr.,Sect.D, 63, 2007
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5YLC
 | | Crystal Structure of MCR-1 Catalytic Domain | | 分子名称: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | | 著者 | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | | 登録日 | 2017-10-17 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
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5YLE
 | | MCR-1 complex with ethanolamine (ETA) | | 分子名称: | ETHANOLAMINE, Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | | 著者 | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | | 登録日 | 2017-10-17 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
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7YIR
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7YIS
 | | Crystal structure of N-terminal PH domain of ARAP3 protein in complex with inositol 1,3,4,5-tetrakisphosphate | | 分子名称: | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 | | 著者 | Zhang, Y.J, Liu, Y.R, Wu, B. | | 登録日 | 2022-07-18 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Int J Mol Sci, 24, 2023
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3SAL
 | | Crystal Structure of Influenza A Virus Neuraminidase N5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | | 著者 | Wang, M.Y, Qi, J.X, Liu, Y, Vavricka, C.J, Wu, Y, Li, Q, Gao, G.F. | | 登録日 | 2011-06-03 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Influenza a virus n5 neuraminidase has an extended 150-cavity
J.Virol., 85, 2011
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8JZ7
 | | Cryo-EM structure of MK-6892-bound HCAR2 in complex with Gi protein | | 分子名称: | 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | 登録日 | 2023-07-04 | | 公開日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2.
Signal Transduct Target Ther, 8, 2023
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7DPD
 | | Human MCM9 N-terminal domain | | 分子名称: | DNA helicase MCM9, SODIUM ION, ZINC ION | | 著者 | Li, J, Liu, L, Liu, Y. | | 登録日 | 2020-12-18 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural study of the N-terminal domain of human MCM8/9 complex.
Structure, 29, 2021
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4FVK
 | | Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Li, Q, Sun, X.M, Li, Z.X, Liu, Y, Vavricka, C.J, Qi, J.X, Gao, G.F. | | 登録日 | 2012-06-29 | | 公開日 | 2012-09-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus
Proc.Natl.Acad.Sci.USA, 109, 2012
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