7P8B
 
 | | Crystal structure of YTHDC1 with compound YLI_DC1_006 | | 分子名称: | 9-cyclopropyl-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 | | 著者 | Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A. | | 登録日 | 2021-07-21 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
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7P8A
 | | Crystal structure of YTHDC1 with compound YLI_DC1_003 | | 分子名称: | SULFATE ION, YTH domain-containing protein 1, ~{N},9-dimethylpurin-6-amine | | 著者 | Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A. | | 登録日 | 2021-07-21 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
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7P87
 | | Crystal structure of YTHDC1 with compound YLI_DC1_001 | | 分子名称: | N-methyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide, SULFATE ION, YTH domain-containing protein 1 | | 著者 | Bedi, R.K, Li, Y, Dolbois, A, Caflisch, A. | | 登録日 | 2021-07-21 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
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7P8F
 | | Crystal structure of YTHDC1 with compound YLI_DC1_008 | | 分子名称: | SULFATE ION, YTH domain-containing protein 1, ~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine | | 著者 | Bedi, R.K, Li, Y, Caflisch, A. | | 登録日 | 2021-07-21 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5, 2022
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7V1N
 | | Structure of the Clade 2 C. difficile TcdB in complex with its receptor TFPI | | 分子名称: | Isoform Beta of Tissue factor pathway inhibitor, Toxin B | | 著者 | Luo, J, Yang, Q, Zhang, X, Zhang, Y, Wan, L, Li, Y, Tao, L. | | 登録日 | 2021-08-05 | | 公開日 | 2022-02-23 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C. difficile.
Cell, 185, 2022
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1G9I
 | | CRYSTAL STRUCTURE OF BETA-TRYSIN COMPLEX IN CYCLOHEXANE | | 分子名称: | BOWMAN-BIRK TYPE TRYPSIN INHIBITOR, CALCIUM ION, SULFATE ION, ... | | 著者 | Zhu, G, Huang, Q, Zhu, Y, Li, Y, Chi, C, Tang, Y. | | 登録日 | 2000-11-24 | | 公開日 | 2000-12-06 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-Ray study on an artificial mung bean inhibitor complex with bovine beta-trypsin in neat cyclohexane.
Biochim.Biophys.Acta, 1546, 2001
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7UFV
 | | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-6766 | | 分子名称: | (3P)-N-[(1S)-3-amino-1-(3-chlorophenyl)-3-oxopropyl]-3-(2-fluorophenyl)-1H-pyrazole-4-carboxamide, DDB1- and CUL4-associated factor 1, UNKNOWN ATOM OR ION | | 著者 | Kimani, S, Li, A, Li, Y, Dong, A, Hutchinson, A, Seitova, A, Wilson, B, Al-Awar, R, Vedadi, M, Brown, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | 登録日 | 2022-03-23 | | 公開日 | 2022-05-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of Nanomolar DCAF1 Small Molecule Ligands.
J.Med.Chem., 66, 2023
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5MSZ
 | | Lytic Polysaccharide Monooxygenase AA15 from Thermobia domestica in the Cu(I) State | | 分子名称: | 1,2-ETHANEDIOL, COPPER (I) ION, Thermobia domestica domestica AA15 | | 著者 | Hemsworth, G.R, Sabbadin, F, Ciano, L, Henrissat, B, Dupree, P, Tryfona, T, Besser, K, Elias, L, Pesante, G, Li, Y, Dowle, A, Bates, R, Gomez, L, Hallam, R, Davies, G.J, Walton, P.H, Bruce, N.C, McQueen-Mason, S. | | 登録日 | 2017-01-06 | | 公開日 | 2018-02-28 | | 最終更新日 | 2018-03-07 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion.
Nat Commun, 9, 2018
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2LAS
 | | Molecular Determinants of Paralogue-Specific SUMO-SIM Recognition | | 分子名称: | M-IR2_peptide, Small ubiquitin-related modifier 1 | | 著者 | Namanja, A, Li, Y, Su, Y, Wong, S, Lu, J, Colson, L, Wu, C, Li, S, Chen, Y. | | 登録日 | 2011-03-20 | | 公開日 | 2011-12-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into High Affinity Small Ubiquitin-like Modifier (SUMO) Recognition by SUMO-interacting Motifs (SIMs) Revealed by a Combination of NMR and Peptide Array Analysis.
J.Biol.Chem., 287, 2012
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8A9W
 | | Crystal structure of PulL C-ter domain | | 分子名称: | SULFATE ION, Type II secretion system protein L | | 著者 | Dazzoni, R, Li, Y, Lopez-Castilla, A, Brier, S, Mechaly, A, Cordier, F, Haouz, A, Nilges, M, Francetic, O, Bardiaux, B, Izadi-Pruneyre, N. | | 登録日 | 2022-06-29 | | 公開日 | 2023-01-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | | 主引用文献 | Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system.
Structure, 31, 2023
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6YM2
 | | Crystal structure of YTHDC1 with compound ADO_AC_25 | | 分子名称: | SULFATE ION, YTHDC1, ~{N},9-dimethylpurin-6-amine | | 著者 | Bedi, R.K, Li, Y, Dolbois, A, Wiedmer, L, Caflisch, A. | | 登録日 | 2020-04-07 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of YTHDC1 with compound ADO_AC_25
To Be Published
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6YM8
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6ZD7
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6ZD4
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6ZD3
 | | Crystal structure of YTHDC1 M438A mutant | | 分子名称: | DI(HYDROXYETHYL)ETHER, SULFATE ION, YTH domain containing 1 | | 著者 | Bedi, R.K, Li, Y, Caflisch, A. | | 登録日 | 2020-06-13 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1.
J Chem Theory Comput, 17, 2021
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8TTH
 | | NorA single mutant - D307N at pH 7.5 | | 分子名称: | Heavy Chain of FabDA1 Variable Domain, Light Chain of FabDA1 Variable Domain, Quinolone resistance protein NorA | | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | | 登録日 | 2023-08-13 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA.
Nat Commun, 15, 2024
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1SLI
 | | LEECH INTRAMOLECULAR TRANS-SIALIDASE COMPLEXED WITH DANA | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, INTRAMOLECULAR TRANS-SIALIDASE | | 著者 | Luo, Y, Li, S.C, Chou, M.Y, Li, Y.T, Luo, M. | | 登録日 | 1998-03-28 | | 公開日 | 1999-04-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of an intramolecular trans-sialidase with a NeuAc alpha2-->3Gal specificity.
Structure, 6, 1998
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1SLL
 | | SIALIDASE L FROM LEECH MACROBDELLA DECORA | | 分子名称: | SIALIDASE L | | 著者 | Luo, Y, Li, S.C, Chou, M.Y, Li, Y.T, Luo, M. | | 登録日 | 1997-10-14 | | 公開日 | 1998-12-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of an intramolecular trans-sialidase with a NeuAc alpha2-->3Gal specificity.
Structure, 6, 1998
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6ZD5
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6ZDA
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6ZD8
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8TTF
 | | NorA double mutant - E222QD307N at pH 7.5 | | 分子名称: | Heavy Chain of FabDA1 Variable Domain, Light Chain of FabDA1 Variable Domain, Quinolone resistance protein NorA | | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | | 登録日 | 2023-08-13 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA.
Nat Commun, 15, 2024
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8TTE
 | | Protonated state of NorA at pH 5.0 | | 分子名称: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | | 登録日 | 2023-08-13 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA.
Nat Commun, 15, 2024
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8TTG
 | | NorA single mutant - E222Q at pH 7.5 | | 分子名称: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | | 登録日 | 2023-08-13 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA.
Nat Commun, 15, 2024
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1FV1
 | | STRUCTURAL BASIS FOR THE BINDING OF AN IMMUNODOMINANT PEPTIDE FROM MYELIN BASIC PROTEIN IN DIFFERENT REGISTERS BY TWO HLA-DR2 ALLELES | | 分子名称: | GLYCEROL, MAJOR HISTOCOMPATIBILITY COMPLEX ALPHA CHAIN, MAJOR HISTOCOMPATIBILITY COMPLEX BETA CHAIN, ... | | 著者 | Li, H, Mariuzza, A.R, Li, Y, Martin, R. | | 登録日 | 2000-09-18 | | 公開日 | 2000-09-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins.
J.Mol.Biol., 304, 2000
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