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7P8F

Crystal structure of YTHDC1 with compound YLI_DC1_008

Summary for 7P8F
Entry DOI10.2210/pdb7p8f/pdb
DescriptorYTH domain-containing protein 1, ~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine, SULFATE ION, ... (4 entities in total)
Functional Keywordsythdc1, inhibitor, complex, m6a, rna binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight42837.06
Authors
Bedi, R.K.,Li, Y.,Caflisch, A. (deposition date: 2021-07-21, release date: 2021-10-20, Last modification date: 2024-01-31)
Primary citationLi, Y.,Bedi, R.K.,Nai, F.,von Roten, V.,Dolbois, A.,Zalesak, F.,Nachawati, R.,Huang, D.,Caflisch, A.
Structure-based design of ligands of the m6A-RNA reader YTHDC1
Eur J Med Chem Rep, 5:100057-, 2022
Cited by
DOI: 10.1016/j.ejmcr.2022.100057
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

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