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PDB: 21374 件

1HOY
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NMR STRUCTURE OF THE COMPLEX BETWEEN A-BUNGAROTOXIN AND A MIMOTOPE OF THE NICOTINIC ACETYLCHOLINE RECEPTOR
分子名称: LONG NEUROTOXIN 1, MIMOTOPE OF THE NICOTINIC ACETYLCHOLINE RECEPTOR
著者Scarselli, M, Spiga, O, Ciutti, A, Bracci, L, Lelli, B, Lozzi, L, Calamandrei, D, Bernini, A, Di Maro, D, Niccolai, N, Neri, P.
登録日2000-12-12
公開日2000-12-27
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献NMR structure of alpha-bungarotoxin free and bound to a mimotope of the nicotinic acetylcholine receptor.
Biochemistry, 41, 2002
2YPT
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Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 mutant (E336A) in complex with a synthetic CSIM tetrapeptide from the C-terminus of prelamin A
分子名称: CAAX PRENYL PROTEASE 1 HOMOLOG, PRELAMIN-A/C, ZINC ION
著者Pike, A.C.W, Dong, Y.Y, Quigley, A, Dong, L, Savitsky, P, Cooper, C.D.O, Chaikuad, A, Goubin, S, Shrestha, L, Li, Q, Mukhopadhyay, S, Yang, J, Xia, X, Shintre, C.A, Barr, A.J, Berridge, G, Chalk, R, Bray, J.E, von Delft, F, Bullock, A, Bountra, C, Arrowsmith, C.H, Edwards, A, Burgess-Brown, N, Carpenter, E.P.
登録日2012-11-01
公開日2012-12-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献The Structural Basis of Zmpste24-Dependent Laminopathies.
Science, 339, 2013
2YDZ
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X-ray structure of the cyan fluorescent protein SCFP3A (K206A mutant)
分子名称: GREEN FLUORESCENT PROTEIN
著者von Stetten, D, Goedhart, J, Noirclerc-Savoye, M, Lelimousin, M, Joosen, L, Hink, M.A, van Weeren, L, Gadella, T.W.J, Royant, A.
登録日2011-03-25
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structure-Guided Evolution of Cyan Fluorescent Proteins Towards a Quantum Yield of 93%
Nat.Commun, 3, 2012
1OVV
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CRYSTAL STRUCTURE OF FOUR-HELIX BUNDLE MODEL di-Co(II)-DF1-L13A (form II)
分子名称: COBALT (II) ION, FOUR-HELIX BUNDLE MODEL di-Co(II)-DF1-L13A (form II)
著者Di Costanzo, L, Geremia, S.
登録日2003-03-27
公開日2004-04-06
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Response of a designed metalloprotein to changes in metal ion coordination, exogenous ligands, and active site volume determined by X-ray crystallography.
J.Am.Chem.Soc., 127, 2005
1Y7V
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X-ray structure of human acid-beta-glucosidase covalently bound to conduritol B epoxide
分子名称: 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glucosylceramidase, ...
著者Premkumar, L, Sawkar, A.R, Boldin-Adamsky, S, Toker, L, Silman, I, Kelly, J.W, Futerman, A.H, Sussman, J.L, Israel Structural Proteomics Center (ISPC)
登録日2004-12-10
公開日2005-04-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease.
J.Biol.Chem., 280, 2005
1OVR
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CRYSTAL STRUCTURE OF FOUR-HELIX BUNDLE MODEL di-Mn(II)-DF1-L13
分子名称: MANGANESE (II) ION, four-helix bundle model di-Mn(II)-DF1-L13
著者Di Costanzo, L, Geremia, S.
登録日2003-03-27
公開日2004-05-18
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Response of a designed metalloprotein to changes in metal ion coordination, exogenous ligands, and active site volume determined by X-ray crystallography.
J.Am.Chem.Soc., 127, 2005
2WKS
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Structure of Helicobacter pylori Type II Dehydroquinase with a new carbasugar-thiophene inhibitor.
分子名称: (1R,4S,5R)-1,4,5-trihydroxy-3-[(5-methyl-1-benzothiophen-2-yl)methoxy]cyclohex-2-ene-1-carboxylic acid, 3-DEHYDROQUINATE DEHYDRATASE
著者Otero, J.M, Guardado-Calvo, P, Llamas-Saiz, A.L, Prazeres, V.F.V, Tizon, L, Castedo, L, Lamb, H, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J.
登録日2009-06-17
公開日2009-11-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues.
J. Med. Chem., 53, 2010
368D
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STRUCTURAL VARIABILITY OF A-DNA IN CRYSTALS OF THE OCTAMER D(PCPCPCPGPCPGPGPG)
分子名称: DNA (5'-D(P*CP*CP*CP*GP*CP*GP*GP*G)-3')
著者Fernandez, L.G, Subirana, J.A, Verdaguer, N, Pyshnyi, D, Campos, L, Malinina, L.
登録日1997-12-19
公開日1998-07-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural variability of A-DNA in crystals of the octamer d(pCpCpCpGpCpGpGpG)
J.Biomol.Struct.Dyn., 15, 1997
1TGL
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BU of 1tgl by Molmil
A SERINE PROTEASE TRIAD FORMS THE CATALYTIC CENTRE OF A TRIACYLGLYCEROL LIPASE
分子名称: TRIACYL-GLYCEROL ACYLHYDROLASE
著者Brady, L, Brzozowski, A.M, Derewenda, Z.S, Dodson, E.J, Dodson, G.G, Tolley, S.P, Turkenburg, J.P, Christiansen, L, Huge-Jensen, B, Norskov, L, Thim, L.
登録日1990-02-05
公開日1990-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A serine protease triad forms the catalytic centre of a triacylglycerol lipase.
Nature, 343, 1990
2Z8N
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Structural basis for the catalytic mechanism of phosphothreonine lyase
分子名称: 27.5 kDa virulence protein, SULFATE ION
著者Chen, L, Wang, H, Gu, L, Huang, N, Zhou, J.M, Chai, J.
登録日2007-09-07
公開日2007-12-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the catalytic mechanism of phosphothreonine lyase.
Nat.Struct.Mol.Biol., 15, 2008
3BB6
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Crystal structure of the P64488 protein from E.coli (strain K12). Northeast Structural Genomics Consortium target ER596
分子名称: Uncharacterized protein yeaR, ZINC ION
著者Kuzin, A.P, Su, M, Seetharaman, J, Wang, D, Janjua, H, Owens, L, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2007-11-09
公開日2007-11-20
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-Ray structure of the P64488 from E.coli (strain K12).
To be Published
3BID
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Crystal structure of the NMB1088 protein from Neisseria meningitidis. Northeast Structural Genomics Consortium target MR91
分子名称: UPF0339 protein NMB1088
著者Forouhar, F, Neely, H, Seetharaman, J, Mao, L, Fang, Y, Xiao, R, Owen, L.A, Maglaqui, M, Cunningham, K, Baran, M.C, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2007-11-30
公開日2007-12-18
最終更新日2020-01-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the NMB1088 protein from Neisseria meningitidis.
To be Published
8WXV
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Structure of WDR5 in complex with WIN motif containing SET1B
分子名称: SET1B, WD repeat-containing protein 5
著者Xu, L, Yang, Y.
登録日2023-10-30
公開日2024-06-26
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode.
J.Biol.Chem., 300, 2024
8Y8E
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Structure of HCoV-HKU1C spike in the inactive-2up conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T.
登録日2024-02-06
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 2024
8WXQ
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Structure of WDR5 in complex with WIN motif containing MBD3C
分子名称: GLY-ALA-ALA-ARG-CYS-ARG-VAL-PHE-SER-PRO, WD repeat-containing protein 5
著者Xu, L, Yang, Y.
登録日2023-10-30
公開日2024-06-26
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode.
J.Biol.Chem., 300, 2024
8WXT
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Structure of WDR5 in complex with WIN motif containing MBD3C R45E/V46G
分子名称: MBD3C, WD repeat-containing protein 5
著者Xu, L, Yang, Y.
登録日2023-10-30
公開日2024-06-26
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode.
J.Biol.Chem., 300, 2024
8Y88
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Structure of HCoV-HKU1C spike in the functionally anchored-2up conformation with 2TMPRSS2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T.
登録日2024-02-06
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 2024
8WXX
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Structure of WDR5 in complex with WIN motif containing SET1B E1750R/G1751V
分子名称: SET1B, WD repeat-containing protein 5
著者Xu, L, Yang, Y.
登録日2023-10-30
公開日2024-06-26
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural studies of WDR5 in complex with MBD3C WIN motif reveal a unique binding mode.
J.Biol.Chem., 300, 2024
8Y7X
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Structure of HCoV-HKU1A spike in the functionally anchored-3up conformation with 3TMPRSS2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T.
登録日2024-02-05
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 2024
8DW9
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Crystal structure of neutralizing antibody D29 Fab in complex with SARS-CoV-2 spike receptor binding domain (RBD)
分子名称: D29 Fab light chain, D29 Heavy chain, Spike protein S1
著者Reddem, E.R, Shapiro, L.
登録日2022-08-01
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2.
Emerg Microbes Infect, 12, 2023
8Y8G
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Structure of HCoV-HKU1C spike in the glycan-activated-1up conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T.
登録日2024-02-06
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 2024
8DXS
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Cryo-EM structure of RBD-directed neutralizing antibody P2B4 in complex with prefusion SARS-CoV-2 spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, P2B4 Heavy chain, P2B4 Light chain, ...
著者Reddem, E.R, Shapiro, L.
登録日2022-08-03
公開日2022-12-07
最終更新日2023-01-18
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2.
Emerg Microbes Infect, 12, 2023
8VAO
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Simulation-driven design of prefusion stabilized SARS-CoV-2 spike S2 antigen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
著者Zhou, L, McLellan, J.S.
登録日2023-12-11
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Simulation-Driven Design of Stabilized SARS-CoV-2 Spike S2 Immunogens
To Be Published
8DWA
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Crystal structure of neutralizing antibody P1D9 Fab in complex with SARS-CoV-2 spike receptor binding domain (RBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, P1D9 Heavy chain, P1D9 Light chain, ...
著者Reddem, E.R, Shapiro, L.
登録日2022-08-01
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2.
Emerg Microbes Infect, 12, 2023
8Y8B
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Local structure of HCoV-HKU1C spike in complex with TMPRSS2 and glycan
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Wang, H.F, Zhang, X, Lu, Y.C, Liu, X.C, Sun, L, Yang, H.T.
登録日2024-02-06
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 2024

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件を2024-07-31に公開中

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