8DWA

Crystal structure of neutralizing antibody P1D9 Fab in complex with SARS-CoV-2 spike receptor binding domain (RBD)

Summary for 8DWA

• Entry DOI: 10.2210/pdb8dwa/pdb
• Descriptor: Spike protein S1, P1D9 Heavy chain, P1D9 Light chain, ... (4 entities in total)
• Functional Keywords: covid-19, sars-cov-2, viral protein, spike glycoprotein, receptor binding protein, rbd, neutralizing antibody, 10-28, fab, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 3
• Total formula weight: 66463.23

Authors

Reddem, E.R.,Shapiro, L. (deposition date: 2022-08-01, release date: 2022-12-07, Last modification date: 2023-10-25)

• Primary citation: Luo, M.,Zhou, B.,Reddem, E.R.,Tang, B.,Chen, B.,Zhou, R.,Liu, H.,Liu, L.,Katsamba, P.S.,Au, K.K.,Man, H.O.,To, K.K.,Yuen, K.Y.,Shapiro, L.,Dang, S.,Ho, D.D.,Chen, Z.; Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2.; Emerg Microbes Infect, 12:2146538-2146538, 2023; PubMed: 36354024; DOI: 10.1080/22221751.2022.2146538

Experimental method

X-RAY DIFFRACTION (3.2 Å)