6TR8
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![BU of 6tr8 by Molmil](/molmil-images/mine/6tr8) | Corynebacterium diphtheriae methionine sulfoxide reductase B (MsrB) solution structure - reduced form | Descriptor: | Peptide-methionine (R)-S-oxide reductase, ZINC ION | Authors: | Volkov, A.N, Tossounian, M.A, Buts, L, Messens, J. | Deposit date: | 2019-12-18 | Release date: | 2020-02-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Methionine sulfoxide reductase B fromCorynebacterium diphtheriaecatalyzes sulfoxide reduction via an intramolecular disulfide cascade. J.Biol.Chem., 295, 2020
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6TPB
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![BU of 6tpb by Molmil](/molmil-images/mine/6tpb) | NMR structure of the apo-form of Pseudomonas fluorescens CopC | Descriptor: | Putative copper resistance protein | Authors: | Persson, K.C, Mayzel, M, Karlsson, B.G, Peciulyte, A, Olsson, L, Wittung Stafshede, P, Salomon Johansen, K, Horvath, I. | Deposit date: | 2019-12-13 | Release date: | 2021-01-13 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | NMR structure of Pseudomonas fluorescens CopC To Be Published
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6TO6
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![BU of 6to6 by Molmil](/molmil-images/mine/6to6) | Solution structure of the modulator of repression (MOR) of the temperate bacteriophage TP901-1 from Lactococcus lactis | Descriptor: | MOR | Authors: | Rasmussen, K.K, Blackledge, M, Herrmann, T, Lo Leggio, L, Jensen, M.R. | Deposit date: | 2019-12-11 | Release date: | 2020-08-19 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage. Proc.Natl.Acad.Sci.USA, 117, 2020
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6TGC
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![BU of 6tgc by Molmil](/molmil-images/mine/6tgc) | CryoEM structure of the ternary DOCK2-ELMO1-RAC1 complex. | Descriptor: | Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 | Authors: | Chang, L, Yang, J, Chang, J.H, Zhang, Z, Boland, A, McLaughlin, S.H, Abu-Thuraia, A, Killoran, R.C, Smith, M.J, Cote, J.F, Barford, D. | Deposit date: | 2019-11-15 | Release date: | 2020-07-29 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state. Nat Commun, 11, 2020
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6U0E
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6U0M
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![BU of 6u0m by Molmil](/molmil-images/mine/6u0m) | Structure of the S. cerevisiae replicative helicase CMG in complex with a forked DNA | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA (15-MER), ... | Authors: | Yuan, Z, Georgescu, R, Bai, L, Zhang, D, O'Donnell, M, Li, H. | Deposit date: | 2019-08-14 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | DNA unwinding mechanism of a eukaryotic replicative CMG helicase. Nat Commun, 11, 2020
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6U3F
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![BU of 6u3f by Molmil](/molmil-images/mine/6u3f) | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | Descriptor: | Panton-Valentine Leucocidin F, SULFATE ION, fos-choline-14 | Authors: | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | Deposit date: | 2019-08-21 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
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6TVL
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![BU of 6tvl by Molmil](/molmil-images/mine/6tvl) | Hen Egg White Lysozyme in complex with a "half sandwich"-type Ru(II) coordination compound | Descriptor: | CHLORIDE ION, Lysozyme C, SODIUM ION, ... | Authors: | Chiniadis, L, Giastas, P, Bratsos, I, Papakyriakou, A. | Deposit date: | 2020-01-10 | Release date: | 2020-04-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.395 Å) | Cite: | High-resolution crystal structures of a "half sandwich"-type Ru(II) coordination compound bound to hen egg-white lysozyme and proteinase K. J.Biol.Inorg.Chem., 25, 2020
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6TXG
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![BU of 6txg by Molmil](/molmil-images/mine/6txg) | Proteinase K in complex with a "half sandwich"-type Ru(II) coordination compound | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, NITRATE ION, ... | Authors: | Chiniadis, L, Giastas, P, Bratsos, I, Papakyriakou, A. | Deposit date: | 2020-01-14 | Release date: | 2020-04-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.372 Å) | Cite: | High-resolution crystal structures of a "half sandwich"-type Ru(II) coordination compound bound to hen egg-white lysozyme and proteinase K. J.Biol.Inorg.Chem., 25, 2020
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6U2S
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![BU of 6u2s by Molmil](/molmil-images/mine/6u2s) | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | Descriptor: | Bi-component leukocidin LukED subunit D, fos-choline-14 | Authors: | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | Deposit date: | 2019-08-20 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
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6U33
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![BU of 6u33 by Molmil](/molmil-images/mine/6u33) | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | Descriptor: | Bi-component leukocidin LukED subunit D, NICKEL (II) ION | Authors: | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | Deposit date: | 2019-08-21 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
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6UAD
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![BU of 6uad by Molmil](/molmil-images/mine/6uad) | Ketosteroid isomerase (C. testosteroni) with truncated & designed loop for precise positioning of a catalytic E38 | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, Ketosteroid isomerase with truncated and designed loop, PHOSPHATE ION | Authors: | Kundert, K, Thompson, M.C, Liu, L, Fraser, J.S, Kortemme, T. | Deposit date: | 2019-09-10 | Release date: | 2020-09-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Ketosteroid isomerase (C. testosteroni) with truncated & designed loop for precise positioning of a catalytic E38 To Be Published
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6U1T
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![BU of 6u1t by Molmil](/molmil-images/mine/6u1t) | Crystal structure of anti-Nipah virus (NiV) F 5B3 antibody Fab fragment | Descriptor: | CHLORIDE ION, antigen-binding (Fab) fragment, heavy chain, ... | Authors: | Dang, H.V, Chan, Y.P, Park, Y.J, Snijder, J, Da Silva, S.C, Vu, B, Yan, L, Feng, Y.R, Rockx, B, Geisbert, T, Mire, C, Mire, C.E, BBroder, C.C, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2019-08-16 | Release date: | 2019-10-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.483 Å) | Cite: | An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections. Nat.Struct.Mol.Biol., 26, 2019
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6U6V
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![BU of 6u6v by Molmil](/molmil-images/mine/6u6v) | Crystal structure of human PD-1H / VISTA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, V-type immunoglobulin domain-containing suppressor of T-cell activation | Authors: | Slater, B.T, Han, X, Chen, L, Xiong, Y. | Deposit date: | 2019-08-30 | Release date: | 2020-01-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insight into T cell coinhibition by PD-1H (VISTA). Proc.Natl.Acad.Sci.USA, 117, 2020
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6TYS
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![BU of 6tys by Molmil](/molmil-images/mine/6tys) | A potent cross-neutralizing antibody targeting the fusion glycoprotein inhibits Nipah virus and Hendra virus infection | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5B3 antibody heavy chain, ... | Authors: | Dang, H.V, Chan, Y.P, Park, Y.J, Snijder, J, Da Silva, S.C, Vu, B, Yan, L, Feng, Y.R, Rockx, B, Geisbert, T, Mire, C.E, Broder, C.B, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2019-08-09 | Release date: | 2019-10-09 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections. Nat.Struct.Mol.Biol., 26, 2019
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6U0F
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6U3T
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![BU of 6u3t by Molmil](/molmil-images/mine/6u3t) | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | Descriptor: | Alpha-hemolysin, SULFATE ION, fos-choline-14 | Authors: | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | Deposit date: | 2019-08-22 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
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6U4P
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![BU of 6u4p by Molmil](/molmil-images/mine/6u4p) | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | Descriptor: | Alpha-hemolysin, SULFATE ION, fos-choline-14 | Authors: | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | Deposit date: | 2019-08-26 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
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6U2T
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6U4Y
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![BU of 6u4y by Molmil](/molmil-images/mine/6u4y) | Crystal Structure of an EZH2-EED Complex in an Oligomeric State | Descriptor: | Histone-lysine N-methyltransferase EZH2, Polycomb protein EED | Authors: | Jiao, L, Liu, X. | Deposit date: | 2019-08-26 | Release date: | 2020-07-08 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | A partially disordered region connects gene repression and activation functions of EZH2. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U0B
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6U8X
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![BU of 6u8x by Molmil](/molmil-images/mine/6u8x) | Crystal structure of DNMT3B-DNMT3L in complex with CpApG DNA | Descriptor: | CpApG DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | Authors: | Gao, L, Song, J. | Deposit date: | 2019-09-06 | Release date: | 2020-06-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.95063877 Å) | Cite: | Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
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6UAU
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![BU of 6uau by Molmil](/molmil-images/mine/6uau) | Crystal structure of a GH128 (subgroup I) endo-beta-1,3-glucanase (E102A mutant) from Amycolatopsis mediterranei (AmGH128_I) in complex with laminaritriose and laminaribiose | Descriptor: | DI(HYDROXYETHYL)ETHER, Glyco_hydro_cc domain-containing protein, ZINC ION, ... | Authors: | Vieira, P.S, Cabral, L, Costa, P.A.C.R, Santos, C.R, Murakami, M.T. | Deposit date: | 2019-09-11 | Release date: | 2020-05-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
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7PFP
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![BU of 7pfp by Molmil](/molmil-images/mine/7pfp) | Full-length cryo-EM structure of the native human uromodulin (UMOD)/Tamm-Horsfall protein (THP) filament | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B. | Deposit date: | 2021-08-11 | Release date: | 2022-03-16 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH. Nat.Struct.Mol.Biol., 29, 2022
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5FCS
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![BU of 5fcs by Molmil](/molmil-images/mine/5fcs) | Diabody | Descriptor: | Diabody, SULFATE ION | Authors: | Mosyak, L, Root, A. | Deposit date: | 2015-12-15 | Release date: | 2016-12-14 | Last modified: | 2019-11-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer. Antibodies, 5, 2016
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