6U3T

Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus

Summary for 6U3T

Entry DOI	10.2210/pdb6u3t/pdb
Descriptor	Alpha-hemolysin, fos-choline-14, SULFATE ION, ... (4 entities in total)
Functional Keywords	alpha-toxin, pvl, leukocidins, mrsa, toxin
Biological source	Staphylococcus aureus
Total number of polymer chains	2
Total formula weight	68544.33
Authors	Liu, J.,Kozhaya, L.,Torres, V.J.,Unutmaz, D.,Lu, M. (deposition date: 2019-08-22, release date: 2020-03-25, Last modification date: 2023-10-11)
Primary citation	Liu, J.,Kozhaya, L.,Torres, V.J.,Unutmaz, D.,Lu, M. Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295:5944-5959, 2020 Cited by PubMed: 32179646 DOI: 10.1074/jbc.RA120.012697 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.79 Å)

Structure validation