6U1T

Crystal structure of anti-Nipah virus (NiV) F 5B3 antibody Fab fragment

Summary for 6U1T

• Entry DOI: 10.2210/pdb6u1t/pdb
• Related: 6TYS
• EMDB information: 20584
• Descriptor: antigen-binding (Fab) fragment, heavy chain, antigen-binding (Fab) fragment, light chain, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: nipah virus, hendra virus, henipavirus, fusion glycoprotein, antibody neutralization, fab, structural genomics, seattle structural genomics center for infectious disease, ssgcid, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 47160.81

Authors

Dang, H.V.,Chan, Y.P.,Park, Y.J.,Snijder, J.,Da Silva, S.C.,Vu, B.,Yan, L.,Feng, Y.R.,Rockx, B.,Geisbert, T.,Mire, C.,Mire, C.E.,BBroder, C.C.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2019-08-16, release date: 2019-10-09, Last modification date: 2023-10-11)

• Primary citation: Dang, H.V.,Chan, Y.P.,Park, Y.J.,Snijder, J.,Da Silva, S.C.,Vu, B.,Yan, L.,Feng, Y.R.,Rockx, B.,Geisbert, T.W.,Mire, C.E.,Broder, C.C.,Veesler, D.; An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections.; Nat.Struct.Mol.Biol., 26:980-987, 2019; PubMed: 31570878; DOI: 10.1038/s41594-019-0308-9

Experimental method

X-RAY DIFFRACTION (1.483 Å)