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PDB: 75 件

1HYJ
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SOLUTION STRUCTURE OF THE EEA1 FYVE DOMAIN
分子名称: ENDOSOME-ASSOCIATED PROTEIN, ZINC ION
著者Kutateladze, T, Overduin, M.
登録日2001-01-19
公開日2001-03-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural mechanism of endosome docking by the FYVE domain.
Science, 291, 2001
1HYI
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SOLUTION STRUCTURE OF THE EEA1 FYVE DOMAIN COMPLEXED WITH INOSITOL 1,3-BISPHOSPHATE
分子名称: ENDOSOME-ASSOCIATED PROTEIN, PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTER, ZINC ION
著者Kutateladze, T, Overduin, M.
登録日2001-01-19
公開日2001-03-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural mechanism of endosome docking by the FYVE domain.
Science, 291, 2001
4X34
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Crystal structure of the 53BP1 tandem tudor domain in complex with p53K381acK382me2
分子名称: THR-SER-ARG-HIS-ALY-MLY-LEU-MET-PHE-LYS, Tumor suppressor p53-binding protein 1
著者Tong, Q, Kutateladze, T.G.
登録日2014-11-27
公開日2015-03-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献An Acetyl-Methyl Switch Drives a Conformational Change in p53.
Structure, 23, 2015
9ATN
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NMR structure of the MLL4 PHD2/3 fingers in complex with ASXL2
分子名称: Histone-lysine N-methyltransferase 2D, Polycomb group protein ASXL2, ZINC ION
著者Zhang, Y, Zandian, M, Kutateladze, T.
登録日2024-02-27
公開日2024-06-19
実験手法SOLUTION NMR
主引用文献ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
Nat Commun, 15, 2024
8F5Q
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Crystal structure of human PCNA in complex with the PIP box of FBH1
分子名称: F-box DNA helicase 1, Proliferating cell nuclear antigen
著者Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T.
登録日2022-11-15
公開日2023-09-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular insight into the PCNA-binding mode of FBH1.
Structure, 31, 2023
6E83
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Solution structure of ZZZ3 ZZ domain in complex with histone H3 tail
分子名称: Histone H3, ZINC ION, ZZ-type zinc finger-containing protein 3
著者Zhang, Y, Kutateladze, T.G.
登録日2018-07-27
公開日2018-09-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation.
Nat Commun, 9, 2018
8GE0
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Crystal structure of JADE1 PZP domain in complex with Histone H3
分子名称: Histone H3.1,Protein Jade-1, ZINC ION
著者Klein, B.J, Liu, J, Kutateladze, T.G.
登録日2023-03-06
公開日2024-03-13
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 31, 2024
8GDX
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Crystal structure of JADE1 PZP domain
分子名称: GLYCEROL, Protein Jade-1, ZINC ION
著者Klein, B.J, Liu, J, Kutateladze, T.G.
登録日2023-03-06
公開日2024-03-13
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 31, 2024
8U77
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Crystal structure of Taf14 in complex with Yng1
分子名称: Protein YNG1, Transcription initiation factor TFIID subunit 14
著者Nguyen, M.C, Wei, P.C, Zhang, G.Y, Kutateladze, T.G.
登録日2023-09-14
公開日2024-08-21
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Molecular insight into interactions between the Taf14, Yng1 and Sas3 subunits of the NuA3 complex.
Nat Commun, 15, 2024
8E4V
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Solution structure of the WH domain of MORF
分子名称: Isoform 3 of Histone acetyltransferase KAT6B
著者Zhang, Y, Kutateladze, T.G.
登録日2022-08-19
公開日2023-05-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.
Nat Commun, 14, 2023
8U2Y
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Solution structure of the PHD6 finger of MLL4 bound to TET3
分子名称: Histone-lysine N-methyltransferase 2D, Methylcytosine dioxygenase TET3, ZINC ION
著者Mohid, S.A, Zandian, M, Zhang, Y, Kutateladze, T.G.
登録日2023-09-06
公開日2024-06-19
実験手法SOLUTION NMR
主引用文献MLL4 binds TET3.
Structure, 32, 2024
6U04
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Crystal structure of human BRPF1 PZP bound to histone H3 tail
分子名称: Histone H3.3,BRPF1, Peregrin, PRASEODYMIUM ION, ...
著者Klein, B.J, Kutateladze, T.G.
登録日2019-08-13
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin.
Structure, 28, 2020
4OUF
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Crystal Structure of CBP bromodomain
分子名称: 1,2-ETHANEDIOL, CREB-binding protein, DI(HYDROXYETHYL)ETHER
著者Roy, S, Das, C, Tyler, J.K, Kutateladze, T.G.
登録日2014-02-17
公開日2014-03-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation.
Proc.Natl.Acad.Sci.USA, 111, 2014
7W9V
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Cryo-EM structure of nucleosome in complex with p300 acetyltransferase catalytic core (complex I)
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Hatazawa, S, Liu, J, Takizawa, Y, Zandian, M, Negishi, L, Kutateladze, T.G, Kurumizaka, H.
登録日2021-12-10
公開日2022-07-13
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Structural basis for binding diversity of acetyltransferase p300 to the nucleosome.
Iscience, 25, 2022
3C6W
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Crystal structure of the ING5 PHD finger in complex with H3K4me3 peptide
分子名称: H3K4me3 histone peptide, Inhibitor of growth protein 5, ZINC ION
著者Champagne, K.S, Pena, P.V, Johnson, K, Kutateladze, T.G.
登録日2008-02-05
公開日2008-06-03
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide.
Proteins, 72, 2008
7K7T
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Crystal structure of human MORC4 ATPase-CW in complex with AMPPNP
分子名称: Isoform 3 of MORC family CW-type zinc finger protein 4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Klein, B.J, Tencer, A.H, Kutateladze, T.G.
登録日2020-09-24
公開日2020-11-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Molecular mechanism of the MORC4 ATPase activation.
Nat Commun, 11, 2020
4HCZ
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PHF1 Tudor in complex with H3K36me3
分子名称: H3L-like histone, PHD finger protein 1
著者Musselman, C.A, Roy, S, Nunez, J, Kutateladze, T.G.
登録日2012-10-01
公開日2012-11-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.
Nat.Struct.Mol.Biol., 19, 2012
1R48
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Solution structure of the C-terminal cytoplasmic domain residues 468-497 of Escherichia coli protein ProP
分子名称: Proline/betaine transporter
著者Zoetewey, D.L, Tripet, B.P, Kutateladze, T.G, Overduin, M.J, Wood, J.M, Hodges, R.S.
登録日2003-10-03
公開日2003-12-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of the C-terminal Antiparallel Coiled-coil Domain from Escherichia coli Osmosensor ProP.
J.Mol.Biol., 334, 2003
7RGW
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Crystal structure of HERC2 DOC domain
分子名称: DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase HERC2
著者Liu, J, Tencer, A.H, Kutateladze, T.G.
登録日2021-07-15
公開日2022-07-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The ZZ domain of HERC2 is a receptor of arginylated substrates.
Sci Rep, 12, 2022
3OQ5
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Crystal structure of the 3-MBT domain from human L3MBTL1 in complex with p53K382me1
分子名称: Cellular tumor antigen p53, Lethal(3)malignant brain tumor-like protein
著者Roy, S, West, L.E, Weiner, K.L, Hayashi, R, Shi, X, Appella, E, Gozani, O, Kutateladze, T.
登録日2010-09-02
公開日2010-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5005 Å)
主引用文献The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression.
J.Biol.Chem., 285, 2010
6AXJ
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Crystal structure of the Yaf9 YEATS domain bound to H3K27ac
分子名称: ALY-SER-ALA-PRO-ALA, GLYCEROL, Protein AF-9 homolog, ...
著者Klein, B.J, Kutateladze, T.G.
登録日2017-09-06
公開日2017-11-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.379 Å)
主引用文献Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.
Nucleic Acids Res., 46, 2018
7LKY
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Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641
分子名称: DIMETHYL SULFOXIDE, Isoform 1 of PHD finger protein 1, Peptidomimetic inhibitor UNC6641, ...
著者Liu, J, Kutateladze, T.G.
登録日2021-02-03
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1).
J.Med.Chem., 64, 2021
7UHE
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Taf14 ET domain in complex with C-terminal tail of Taf2
分子名称: C-terminal tail of Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Kutateladze, T.G.
登録日2022-03-26
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Taf2 mediates DNA binding of Taf14.
Nat Commun, 13, 2022
7MJU
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Crystal structure of human AF10 PZP bound to histone H3 tail
分子名称: Histone H3.1,Protein AF-10, ZINC ION
著者Klein, B.J, Kutateladze, T.G.
登録日2021-04-20
公開日2021-08-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations.
Nat Commun, 12, 2021
7TRL
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Crystal structure of human BIRC2 BIR3 domain in complex with histone H3
分子名称: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 2, Histone H3, ...
著者Klein, B.J, Tencer, A.H, Kutateladze, T.G.
登録日2022-01-29
公開日2023-08-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.
Nat.Struct.Mol.Biol., 30, 2023

 

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