7TRL

Crystal structure of human BIRC2 BIR3 domain in complex with histone H3

Summary for 7TRL

Entry DOI	10.2210/pdb7trl/pdb
Descriptor	Baculoviral IAP repeat-containing protein 2, Histone H3, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	nuclear protein, inhibitor, histone h3, dna binding, apoptosis
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	12572.57
Authors	Klein, B.J.,Tencer, A.H.,Kutateladze, T.G. (deposition date: 2022-01-29, release date: 2023-08-02, Last modification date: 2023-09-20)
Primary citation	Tencer, A.H.,Yu, Y.,Causse, S.Z.,Campbell, G.R.,Klein, B.J.,Xuan, H.,Cartier, J.,Miles, M.A.,Gaurav, N.,Zadoroznyj, A.,Holt, T.A.,Wen, H.,Hawkins, C.J.,Spector, S.A.,Dubrez, L.,Shi, X.,Kutateladze, T.G. Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2. Nat.Struct.Mol.Biol., 30:1265-1274, 2023 Cited by PubMed: 37524969 DOI: 10.1038/s41594-023-01044-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation