7TRL
Crystal structure of human BIRC2 BIR3 domain in complex with histone H3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Baculoviral IAP repeat-containing protein 2 | polymer | 94 | 10826.3 | 1 | UniProt (Q13490) Pfam (PF00653) | Homo sapiens (human) | Cellular inhibitor of apoptosis 1,C-IAP1,IAP homolog B,Inhibitor of apoptosis protein 2,hIAP-2,hIAP2,RING finger protein 48,RING-type E3 ubiquitin transferase BIRC2,TNFR2-TRAF-signaling complex protein 2 |
| 2 | B (B) | Histone H3 | polymer | 12 | 1308.5 | 1 | UniProt (by SIFTS) (Q6NXT2) | Homo sapiens | |
| 3 | C, D, E, F, G... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | I (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A: 261 - 346 (UniProt: Q13490)
| PDB | External Database | Details |
|---|---|---|
| Gly 253 | - | expression tag |
| Pro 254 | - | expression tag |
| Leu 255 | - | expression tag |
| Gly 256 | - | expression tag |
| Ser 257 | - | expression tag |
| Pro 258 | - | expression tag |
| Glu 259 | - | expression tag |
| Phe 260 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 12134.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 437.8 | |
| All* | Total formula weight | 12572.6 |
