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PDB: 81 results

1HYJ
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SOLUTION STRUCTURE OF THE EEA1 FYVE DOMAIN
Descriptor: ENDOSOME-ASSOCIATED PROTEIN, ZINC ION
Authors:Kutateladze, T, Overduin, M.
Deposit date:2001-01-19
Release date:2001-03-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural mechanism of endosome docking by the FYVE domain.
Science, 291, 2001
1HYI
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SOLUTION STRUCTURE OF THE EEA1 FYVE DOMAIN COMPLEXED WITH INOSITOL 1,3-BISPHOSPHATE
Descriptor: ENDOSOME-ASSOCIATED PROTEIN, PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTER, ZINC ION
Authors:Kutateladze, T, Overduin, M.
Deposit date:2001-01-19
Release date:2001-03-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural mechanism of endosome docking by the FYVE domain.
Science, 291, 2001
7UHE
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Taf14 ET domain in complex with C-terminal tail of Taf2
Descriptor: C-terminal tail of Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 14
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2022-03-26
Release date:2022-08-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Taf2 mediates DNA binding of Taf14.
Nat Commun, 13, 2022
4X34
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Crystal structure of the 53BP1 tandem tudor domain in complex with p53K381acK382me2
Descriptor: THR-SER-ARG-HIS-ALY-MLY-LEU-MET-PHE-LYS, Tumor suppressor p53-binding protein 1
Authors:Tong, Q, Kutateladze, T.G.
Deposit date:2014-11-27
Release date:2015-03-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:An Acetyl-Methyl Switch Drives a Conformational Change in p53.
Structure, 23, 2015
9EHI
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BU of 9ehi by Molmil
Crystal structure of ENL YEATS in complex with histone H3 methacrylated at K18
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Histone H3.1, Protein ENL
Authors:Becht, D.C, Selvam, K, Kutateladze, T.G.
Deposit date:2024-11-22
Release date:2025-04-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of ENL YEATS in complex with histone H3 methacrylated at K18
To Be Published
3C6W
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BU of 3c6w by Molmil
Crystal structure of the ING5 PHD finger in complex with H3K4me3 peptide
Descriptor: H3K4me3 histone peptide, Inhibitor of growth protein 5, ZINC ION
Authors:Champagne, K.S, Pena, P.V, Johnson, K, Kutateladze, T.G.
Deposit date:2008-02-05
Release date:2008-06-03
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide.
Proteins, 72, 2008
2QIC
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Crystal Structure of the ING1 PHD Finger in complex with a Histone H3K4ME3 peptide
Descriptor: H3K4ME3 PEPTIDE, Inhibitor of growth protein 1, ZINC ION
Authors:Pena, P.V, Champagne, K, Zhao, R, Kutateladze, T.G.
Deposit date:2007-07-03
Release date:2008-05-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.
J.Mol.Biol., 380, 2008
2G6Q
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BU of 2g6q by Molmil
Crystal structure of ING2 PHD finger in complex with H3K4Me3 peptide
Descriptor: H3K4Me3 peptide, Inhibitor of growth protein 2, ZINC ION
Authors:Pena, P.V, Zhao, R, Kutateladze, T.G.
Deposit date:2006-02-24
Release date:2006-07-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2.
Nature, 442, 2006
8GE0
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Crystal structure of JADE1 PZP domain in complex with Histone H3
Descriptor: Histone H3.1,Protein Jade-1, ZINC ION
Authors:Klein, B.J, Liu, J, Kutateladze, T.G.
Deposit date:2023-03-06
Release date:2024-03-13
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 31, 2024
8F5Q
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Crystal structure of human PCNA in complex with the PIP box of FBH1
Descriptor: F-box DNA helicase 1, Proliferating cell nuclear antigen
Authors:Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T.
Deposit date:2022-11-15
Release date:2023-09-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular insight into the PCNA-binding mode of FBH1.
Structure, 31, 2023
8GDX
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BU of 8gdx by Molmil
Crystal structure of JADE1 PZP domain
Descriptor: GLYCEROL, Protein Jade-1, ZINC ION
Authors:Klein, B.J, Liu, J, Kutateladze, T.G.
Deposit date:2023-03-06
Release date:2024-03-13
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 31, 2024
8U77
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Crystal structure of Taf14 in complex with Yng1
Descriptor: Protein YNG1, Transcription initiation factor TFIID subunit 14
Authors:Nguyen, M.C, Wei, P.C, Zhang, G.Y, Kutateladze, T.G.
Deposit date:2023-09-14
Release date:2024-08-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Molecular insight into interactions between the Taf14, Yng1 and Sas3 subunits of the NuA3 complex.
Nat Commun, 15, 2024
6AXJ
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Crystal structure of the Yaf9 YEATS domain bound to H3K27ac
Descriptor: ALY-SER-ALA-PRO-ALA, GLYCEROL, Protein AF-9 homolog, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.379 Å)
Cite:Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.
Nucleic Acids Res., 46, 2018
9ATN
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BU of 9atn by Molmil
NMR structure of the MLL4 PHD2/3 fingers in complex with ASXL2
Descriptor: Histone-lysine N-methyltransferase 2D, Polycomb group protein ASXL2, ZINC ION
Authors:Zhang, Y, Zandian, M, Kutateladze, T.
Deposit date:2024-02-27
Release date:2024-06-19
Method:SOLUTION NMR
Cite:ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
Nat Commun, 15, 2024
8U2Y
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Solution structure of the PHD6 finger of MLL4 bound to TET3
Descriptor: Histone-lysine N-methyltransferase 2D, Methylcytosine dioxygenase TET3, ZINC ION
Authors:Mohid, S.A, Zandian, M, Zhang, Y, Kutateladze, T.G.
Deposit date:2023-09-06
Release date:2024-06-19
Method:SOLUTION NMR
Cite:MLL4 binds TET3.
Structure, 32, 2024
6U04
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Crystal structure of human BRPF1 PZP bound to histone H3 tail
Descriptor: Histone H3.3,BRPF1, Peregrin, PRASEODYMIUM ION, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2019-08-13
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin.
Structure, 28, 2020
7W9V
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BU of 7w9v by Molmil
Cryo-EM structure of nucleosome in complex with p300 acetyltransferase catalytic core (complex I)
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Hatazawa, S, Liu, J, Takizawa, Y, Zandian, M, Negishi, L, Kutateladze, T.G, Kurumizaka, H.
Deposit date:2021-12-10
Release date:2022-07-13
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural basis for binding diversity of acetyltransferase p300 to the nucleosome.
Iscience, 25, 2022
4OUF
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Crystal Structure of CBP bromodomain
Descriptor: 1,2-ETHANEDIOL, CREB-binding protein, DI(HYDROXYETHYL)ETHER
Authors:Roy, S, Das, C, Tyler, J.K, Kutateladze, T.G.
Deposit date:2014-02-17
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation.
Proc.Natl.Acad.Sci.USA, 111, 2014
4HCZ
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PHF1 Tudor in complex with H3K36me3
Descriptor: H3L-like histone, PHD finger protein 1
Authors:Musselman, C.A, Roy, S, Nunez, J, Kutateladze, T.G.
Deposit date:2012-10-01
Release date:2012-11-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.
Nat.Struct.Mol.Biol., 19, 2012
1R48
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BU of 1r48 by Molmil
Solution structure of the C-terminal cytoplasmic domain residues 468-497 of Escherichia coli protein ProP
Descriptor: Proline/betaine transporter
Authors:Zoetewey, D.L, Tripet, B.P, Kutateladze, T.G, Overduin, M.J, Wood, J.M, Hodges, R.S.
Deposit date:2003-10-03
Release date:2003-12-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of the C-terminal Antiparallel Coiled-coil Domain from Escherichia coli Osmosensor ProP.
J.Mol.Biol., 334, 2003
9ARO
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BU of 9aro by Molmil
Crystal structure of AF9 YEATS domain in complex with acetylated at K1007 MOZ
Descriptor: Acetylated Peptide from Histone acetyltransferase KAT6A, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ...
Authors:Selvam, K, Kutateladze, T.G.
Deposit date:2024-02-23
Release date:2025-01-22
Last modified:2025-04-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A multivalent engagement of ENL with MOZ.
Nat.Struct.Mol.Biol., 32, 2025
7RGW
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Crystal structure of HERC2 DOC domain
Descriptor: DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase HERC2
Authors:Liu, J, Tencer, A.H, Kutateladze, T.G.
Deposit date:2021-07-15
Release date:2022-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The ZZ domain of HERC2 is a receptor of arginylated substrates.
Sci Rep, 12, 2022
8VLD
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BU of 8vld by Molmil
Crystal structure of Ash1L PHD finger in complex with histone H3K4me2
Descriptor: Histone H3.3C, Histone-lysine N-methyltransferase ASH1L, ZINC ION
Authors:Vann, K.R, Kutateladze, T.G.
Deposit date:2024-01-11
Release date:2025-03-19
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure-function relationship of ASH1L and histone H3K36 and H3K4 methylation.
Nat Commun, 16, 2025
8VLF
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Crystal structure of Ash1L PHD finger in complex with histone H3K4me3
Descriptor: Histone H3.3C, Histone-lysine N-methyltransferase ASH1L, ZINC ION
Authors:Vann, K.R, Kutateladze, T.G.
Deposit date:2024-01-11
Release date:2025-03-19
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Structure-function relationship of ASH1L and histone H3K36 and H3K4 methylation.
Nat Commun, 16, 2025
9ARR
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BU of 9arr by Molmil
Crystal structure of AF9 YEATS domain in complex with dicrotonylated at K1007 and K1014 MOZ
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Histone acetyltransferase KAT6A, ...
Authors:Selvam, K, Kutateladze, T.G.
Deposit date:2024-02-23
Release date:2025-01-22
Last modified:2025-04-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A multivalent engagement of ENL with MOZ.
Nat.Struct.Mol.Biol., 32, 2025

 

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