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2QIC

Crystal Structure of the ING1 PHD Finger in complex with a Histone H3K4ME3 peptide

Summary for 2QIC
Entry DOI10.2210/pdb2qic/pdb
DescriptorInhibitor of growth protein 1, H3K4ME3 PEPTIDE, ZINC ION, ... (4 entities in total)
Functional Keywordsphd, ing1, histone, h3k4me3, chromatin, antitumor protein, apoptosis
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus (Probable): Q9UK53
Total number of polymer chains2
Total formula weight8557.31
Authors
Pena, P.V.,Champagne, K.,Zhao, R.,Kutateladze, T.G. (deposition date: 2007-07-03, release date: 2008-05-13, Last modification date: 2023-08-30)
Primary citationPena, P.V.,Hom, R.A.,Hung, T.,Lin, H.,Kuo, A.J.,Wong, R.P.,Subach, O.M.,Champagne, K.S.,Zhao, R.,Verkhusha, V.V.,Li, G.,Gozani, O.,Kutateladze, T.G.
Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.
J.Mol.Biol., 380:303-312, 2008
Cited by
PubMed: 18533182
DOI: 10.1016/j.jmb.2008.04.061
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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