1MBC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mbc by Molmil](/molmil-images/mine/1mbc) | |
2TPR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2tpr by Molmil](/molmil-images/mine/2tpr) | |
2MA2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ma2 by Molmil](/molmil-images/mine/2ma2) | Solution structure of RasGRP2 EF hands bound to calcium | 分子名称: | RAS guanyl-releasing protein 2 | 著者 | Kuriyan, J, Iwig, J, Vercoulen, Y, Das, R, Barros, T, Limnander, A, Che, Y, Pelton, J, Wemmer, D, Roose, J. | 登録日 | 2013-06-24 | 公開日 | 2013-08-21 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1. Elife, 2, 2013
|
|
1TRB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1trb by Molmil](/molmil-images/mine/1trb) | |
3KL8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kl8 by Molmil](/molmil-images/mine/3kl8) | CaMKIINtide Inhibitor Complex | 分子名称: | Calcium/calmodulin dependent protein kinase II, Calcium/calmodulin-dependent protein kinase II inhibitor 1 | 著者 | Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H. | 登録日 | 2009-11-06 | 公開日 | 2010-02-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.372 Å) | 主引用文献 | Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Nat.Struct.Mol.Biol., 17, 2010
|
|
3KK9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kk9 by Molmil](/molmil-images/mine/3kk9) | CaMKII Substrate Complex B | 分子名称: | Calcium/calmodulin dependent protein kinase II | 著者 | Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H. | 登録日 | 2009-11-04 | 公開日 | 2010-02-09 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (3.206 Å) | 主引用文献 | Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Nat.Struct.Mol.Biol., 17, 2010
|
|
3KK8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kk8 by Molmil](/molmil-images/mine/3kk8) | CaMKII Substrate Complex A | 分子名称: | Calcium/calmodulin dependent protein kinase II, MAGNESIUM ION | 著者 | Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H. | 登録日 | 2009-11-04 | 公開日 | 2010-02-09 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Nat.Struct.Mol.Biol., 17, 2010
|
|
1A06
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1a06 by Molmil](/molmil-images/mine/1a06) | |
1BF5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bf5 by Molmil](/molmil-images/mine/1bf5) | TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX | 分子名称: | DNA (5'-D(*AP*CP*AP*GP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*G P*C)-3'), DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*CP*T P*G)-3'), SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA | 著者 | Kuriyan, J, Zhao, Y, Chen, X, Vinkemeier, U, Jeruzalmi, D, Darnell Jr, J.E. | 登録日 | 1998-05-27 | 公開日 | 1998-08-12 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell(Cambridge,Mass.), 93, 1998
|
|
7SA7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sa7 by Molmil](/molmil-images/mine/7sa7) | |
1EQN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1eqn by Molmil](/molmil-images/mine/1eqn) | |
5WDS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wds by Molmil](/molmil-images/mine/5wds) | Choanoflagellate Salpingoeca rosetta Ras with GDP bound | 分子名称: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kondo, Y, Gee, C.L, Kuriyan, J. | 登録日 | 2017-07-05 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Deconstruction of the Ras switching cycle through saturation mutagenesis. Elife, 6, 2017
|
|
5WDO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wdo by Molmil](/molmil-images/mine/5wdo) | H-Ras bound to GMP-PNP at 277K | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Cofsky, J.C, Bandaru, P, Gee, C.L, Kuriyan, J. | 登録日 | 2017-07-05 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Deconstruction of the Ras switching cycle through saturation mutagenesis. Elife, 6, 2017
|
|
5IG5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ig5 by Molmil](/molmil-images/mine/5ig5) | |
6UAN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uan by Molmil](/molmil-images/mine/6uan) | B-Raf:14-3-3 complex | 分子名称: | 14-3-3 zeta, Serine/threonine-protein kinase B-raf | 著者 | Kondo, Y, Ognjenovic, J, Banerjee, S, Karandur, D, Merk, A, Kulhanek, K, Wong, K, Roose, J.P, Subramaniam, S, Kuriyan, J. | 登録日 | 2019-09-11 | 公開日 | 2019-09-25 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases. Science, 366, 2019
|
|
2RFE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rfe by Molmil](/molmil-images/mine/2rfe) | Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide | 分子名称: | ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor | 著者 | Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J. | 登録日 | 2007-09-28 | 公開日 | 2007-12-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature, 450, 2007
|
|
2RF9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rf9 by Molmil](/molmil-images/mine/2rf9) | Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide | 分子名称: | ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor | 著者 | Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J. | 登録日 | 2007-09-28 | 公開日 | 2007-12-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature, 450, 2007
|
|
2GS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gs6 by Molmil](/molmil-images/mine/2gs6) | Crystal Structure of the active EGFR kinase domain in complex with an ATP analog-peptide conjugate | 分子名称: | CHLORIDE ION, Epidermal growth factor receptor, Peptide, ... | 著者 | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | 登録日 | 2006-04-25 | 公開日 | 2006-06-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor Cell(Cambridge,Mass.), 125, 2006
|
|
6OF9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6of9 by Molmil](/molmil-images/mine/6of9) | |
4L9M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4l9m by Molmil](/molmil-images/mine/4l9m) | Autoinhibited state of the Ras-specific exchange factor RasGRP1 | 分子名称: | CITRIC ACID, GLYCEROL, RAS guanyl-releasing protein 1, ... | 著者 | Iwig, J.S, Vercoulen, Y, Das, R, Barros, T, Limnander, A, Che, Y, Pelton, J.G, Wemmer, D.E, Roose, J.P, Kuriyan, J. | 登録日 | 2013-06-18 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1. Elife, 2, 2013
|
|
7REC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rec by Molmil](/molmil-images/mine/7rec) | Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CaMKII alpha hub bound to 5-HDC | 分子名称: | 5-hydroxydiclofenac, Calcium/calmodulin-dependent protein kinase type II subunit alpha, SODIUM ION | 著者 | McSpadden, E.D, Chi, C.C, Gee, C.L, Kuriyan, J. | 登録日 | 2021-07-12 | 公開日 | 2021-07-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | GHB analogs confer neuroprotection through specific interaction with the CaMKII alpha hub domain. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
8UNF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8unf by Molmil](/molmil-images/mine/8unf) | Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp and DNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Sliding clamp, ... | 著者 | Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J. | 登録日 | 2023-10-18 | 公開日 | 2023-12-13 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
|
|
8E4T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e4t by Molmil](/molmil-images/mine/8e4t) | Crystal structure of the kinase domain of RTKC8 from the choanoflagellate Monosiga brevicollis | 分子名称: | PHOSPHATE ION, RTKC8 Kinase domain, STAUROSPORINE | 著者 | Bajaj, T, Gee, C.L, Kuriyan, J. | 登録日 | 2022-08-18 | 公開日 | 2023-06-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of the kinase domain of a receptor tyrosine kinase from a choanoflagellate, Monosiga brevicollis. Plos One, 18, 2023
|
|
8UNH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8unh by Molmil](/molmil-images/mine/8unh) | Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Sliding clamp, ... | 著者 | Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J. | 登録日 | 2023-10-19 | 公開日 | 2023-12-13 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
|
|
6OF8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6of8 by Molmil](/molmil-images/mine/6of8) | Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CamKII-alpha hub domain | 分子名称: | Calcium/calmodulin-dependent protein kinase type II subunit alpha, GLYCEROL, POTASSIUM ION | 著者 | McSpadden, E.D, Chi, C.C, Gee, C.L, Kuriyan, J. | 登録日 | 2019-03-28 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+/calmodulin-dependent protein kinase II. Protein Sci., 28, 2019
|
|