7SA7

Crystal structure of the apo SH2 domains of Syk

Summary for 7SA7

Entry DOI	10.2210/pdb7sa7/pdb
Descriptor	Tyrosine-protein kinase SYK (2 entities in total)
Functional Keywords	kinase, sh2 domain, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	6
Total formula weight	180673.27
Authors	Hobbs, H.T.,Badroos, J.,Gee, C.L.,Kuriyan, J. (deposition date: 2021-09-22, release date: 2021-10-13, Last modification date: 2023-10-18)
Primary citation	Hobbs, H.T.,Shah, N.H.,Badroos, J.M.,Gee, C.L.,Marqusee, S.,Kuriyan, J. Differences in the dynamics of the tandem-SH2 modules of the Syk and ZAP-70 tyrosine kinases. Protein Sci., 30:2373-2384, 2021 Cited by PubMed: 34601763 DOI: 10.1002/pro.4199 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation