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PDB: 243 件
2V8H
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Crystal structure of mutant E159A of beta-alanine synthase from Saccharomyces kluyveri in complex with its substrate N-carbamyl-beta- alanine
分子名称: BETA-ALANINE SYNTHASE, BICINE, N-(AMINOCARBONYL)-BETA-ALANINE, ...
著者Lundgren, S, Andersen, B, Piskur, J, Dobritzsch, D.
登録日2007-08-08
公開日2007-10-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
2V8D
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Crystal structure of mutant E159A of beta-alanine synthase from Saccharomyces kluyveri
分子名称: BETA-ALANINE SYNTHASE, ZINC ION
著者Lundgren, S, Andersen, B, Piskur, J, Dobritzsch, D.
登録日2007-08-07
公開日2007-10-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
6OF9
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BU of 6of9 by Molmil
Structure of the Chlamydamonas reinhardtii CamKII hub homology domain
分子名称: CaMKII hub
著者McSpadden, E.D, Chi, C.C, Gee, C.L, Kuriyan, J.
登録日2019-03-28
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+/calmodulin-dependent protein kinase II.
Protein Sci., 28, 2019
5CNO
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BU of 5cno by Molmil
Crystal structure of the EGFR kinase domain mutant V924R
分子名称: Epidermal growth factor receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Kovacs, E, Das, R, Mirza, A, Jura, N, Barros, T, Kuriyan, J.
登録日2015-07-17
公開日2015-07-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor.
Mol.Cell.Biol., 35, 2015
1FPU
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BU of 1fpu by Molmil
CRYSTAL STRUCTURE OF ABL KINASE DOMAIN IN COMPLEX WITH A SMALL MOLECULE INHIBITOR
分子名称: N-[4-METHYL-3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-3-PYRIDINECARBOXAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL
著者Schindler, T, Bornmann, W, Pellicena, P, Miller, W.T, Clarkson, B, Kuriyan, J.
登録日2000-08-31
公開日2000-09-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural mechanism for STI-571 inhibition of abelson tyrosine kinase.
Science, 289, 2000
5CNN
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BU of 5cnn by Molmil
Crystal structure of the EGFR kinase domain mutant I682Q
分子名称: Epidermal growth factor receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Kovacs, E, Das, R, Mirza, A, Jura, N, Barros, T, Kuriyan, J.
登録日2015-07-17
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor.
Mol.Cell.Biol., 35, 2015
2GS7
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BU of 2gs7 by Molmil
Crystal Structure of the inactive EGFR kinase domain in complex with AMP-PNP
分子名称: Epidermal growth factor receptor, IODIDE ION, MAGNESIUM ION, ...
著者Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J.
登録日2006-04-25
公開日2006-06-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
Cell(Cambridge,Mass.), 125, 2006
5BNB
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BU of 5bnb by Molmil
Crystal structure of a Ube2S-ubiquitin conjugate
分子名称: Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 S
著者Lorenz, S.G, Feiler, C.G, Kuriyan, J.
登録日2015-05-25
公開日2016-02-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Crystal Structure of a Ube2S-Ubiquitin Conjugate.
Plos One, 11, 2016
2GS2
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BU of 2gs2 by Molmil
Crystal Structure of the active EGFR kinase domain
分子名称: Epidermal growth factor receptor
著者Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J.
登録日2006-04-25
公開日2006-06-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor.
Cell(Cambridge,Mass.), 125, 2006
1OPJ
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BU of 1opj by Molmil
Structural basis for the auto-inhibition of c-Abl tyrosine kinase
分子名称: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, MYRISTIC ACID, ...
著者Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J.
登録日2003-03-06
公開日2003-04-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003
1AQC
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BU of 1aqc by Molmil
X11 PTB DOMAIN-10MER PEPTIDE COMPLEX
分子名称: PEPTIDE, X11
著者Lee, C.-H, Zhang, Z, Kuriyan, J.
登録日1997-07-28
公開日1997-12-24
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
EMBO J., 16, 1997
1AYA
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BU of 1aya by Molmil
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
分子名称: PEPTIDE PDGFR-1009, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
著者Lee, C.-H, Kuriyan, J.
登録日1994-05-15
公開日1994-08-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
1AYC
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CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
分子名称: PEPTIDE PDGFR-740, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
著者Lee, C.-H, Kuriyan, J.
登録日1994-05-15
公開日1994-08-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
3ET6
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BU of 3et6 by Molmil
The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase
分子名称: PHOSPHATE ION, Soluble guanylyl cyclase beta
著者Winger, J.A, Derbyshire, E.R, Lamers, M.H, Marletta, M.A, Kuriyan, J.
登録日2008-10-07
公開日2008-10-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase.
Bmc Struct.Biol., 8, 2008
2J9R
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BU of 2j9r by Molmil
Thymidine kinase from B. anthracis in complex with dT.
分子名称: PHOSPHATE ION, THYMIDINE, THYMIDINE KINASE, ...
著者Kosinska, U, Carnrot, C, Sandrini, M.P.B, Clausen, A.R, Wang, L, Piskur, J, Eriksson, S, Eklund, H.
登録日2006-11-15
公開日2007-01-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
3SOA
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BU of 3soa by Molmil
Full-length human CaMKII
分子名称: 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile, Calcium/calmodulin-dependent protein kinase type II subunit alpha with a beta 7 linker
著者Chao, L.H, Kuriyan, J.
登録日2011-06-30
公開日2011-08-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.5501 Å)
主引用文献A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca(2+)/Calmodulin- Dependent Kinase II Holoenzyme.
Cell(Cambridge,Mass.), 146, 2011
2JA1
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BU of 2ja1 by Molmil
Thymidine kinase from B. cereus with TTP bound as phosphate donor.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, THYMIDINE KINASE, THYMIDINE-5'-TRIPHOSPHATE, ...
著者Kosinska, U, Carnrot, C, Sandrini, M.P.B, Clausen, A.R, Wang, L, Piskur, J, Eriksson, S, Eklund, H.
登録日2006-11-17
公開日2007-01-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
1AYD
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BU of 1ayd by Molmil
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
分子名称: PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
著者Lee, C.-H, Kuriyan, J.
登録日1994-05-15
公開日1994-08-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
1AYB
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BU of 1ayb by Molmil
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
分子名称: PEPTIDE IRS-1-895, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
著者Lee, C.-H, Kuriyan, J.
登録日1994-05-15
公開日1994-08-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
3FW1
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BU of 3fw1 by Molmil
Quinone Reductase 2
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Winger, J.A, Hantschel, O, Superti-Furga, G, Kuriyan, J.
登録日2009-01-16
公開日2009-03-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2).
Bmc Struct.Biol., 9, 2009
1CZD
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BU of 1czd by Molmil
CRYSTAL STRUCTURE OF THE PROCESSIVITY CLAMP GP45 FROM BACTERIOPHAGE T4
分子名称: DNA POLYMERASE ACCESSORY PROTEIN G45
著者Moarefi, I, Jeruzalmi, D, Turner, J, O'Donnell, M, Kuriyan, J.
登録日1999-09-02
公開日2000-03-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage.
J.Mol.Biol., 296, 2000
1PLQ
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BU of 1plq by Molmil
CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA
分子名称: MERCURY (II) ION, PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
著者Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J.
登録日1995-01-02
公開日1995-03-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA.
Cell(Cambridge,Mass.), 79, 1994
1PLR
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CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA
分子名称: PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
著者Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J.
登録日1995-01-02
公開日1995-03-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA.
Cell(Cambridge,Mass.), 79, 1994
1OPK
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BU of 1opk by Molmil
Structural basis for the auto-inhibition of c-Abl tyrosine kinase
分子名称: 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ...
著者Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J.
登録日2003-03-06
公開日2003-04-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003
1OPL
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Structural basis for the auto-inhibition of c-Abl tyrosine kinase
分子名称: 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, MYRISTIC ACID, proto-oncogene tyrosine-protein kinase
著者Nagar, B, Hantschel, O, Young, M.A, Scheffzek, K, Veach, D, Bornmann, W, Clarkson, B, Superti-Furga, G, Kuriyan, J.
登録日2003-03-06
公開日2003-04-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Structural basis for the autoinhibition of c-Abl tyrosine kinase
Cell(Cambridge,Mass.), 112, 2003

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