3SOA

Full-length human CaMKII

Summary for 3SOA

Entry DOI	10.2210/pdb3soa/pdb
Descriptor	Calcium/calmodulin-dependent protein kinase type II subunit alpha with a beta 7 linker, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile (2 entities in total)
Functional Keywords	kinase, protein kinase, phosphorylation, calcium/calmodulin, cytosolic, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cell junction, synapse, presynaptic cell membrane (By similarity): Q9UQM7
Total number of polymer chains	1
Total formula weight	51176.45
Authors	Chao, L.H.,Kuriyan, J. (deposition date: 2011-06-30, release date: 2011-08-31, Last modification date: 2023-09-13)
Primary citation	Chao, L.H.,Stratton, M.M.,Lee, I.H.,Rosenberg, O.S.,Levitz, J.,Mandell, D.J.,Kortemme, T.,Groves, J.T.,Schulman, H.,Kuriyan, J. A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca(2+)/Calmodulin- Dependent Kinase II Holoenzyme. Cell(Cambridge,Mass.), 146:732-745, 2011 Cited by PubMed: 21884935 DOI: 10.1016/j.cell.2011.07.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5501 Å)

Structure validation