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PDB: 262 results

8TQS
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BU of 8tqs by Molmil
Complex of human thrombin (S195A) bound to a bivalent inhibitor comprised of DNA Aptamer HD22 conjugated to Dabigatran with a linker.
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (30-MER), ...
Authors:Krishnaswamy, S, Kumar, S.
Deposit date:2023-08-08
Release date:2024-05-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.207 Å)
Cite:Aptameric hirudins as selective and reversible EXosite-ACTive site (EXACT) inhibitors.
Nat Commun, 15, 2024
7EWO
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BU of 7ewo by Molmil
Crystal Structure of D67A, E68P double mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae
Descriptor: Cysteine synthase
Authors:Rahisuddin, R, Ekka, M.K, Singh, A.K, Saini, N, Patel, M, Kumar, N, Kumaran, S.
Deposit date:2021-05-25
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of D67A, E68P double mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae
To Be Published
8FXT
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BU of 8fxt by Molmil
Escherichia coli periplasmic Glucose-Binding Protein glucose complex: Acrylodan conjugate attached at W183C
Descriptor: 1-[6-(dimethylamino)naphthalen-2-yl]propan-1-one, CALCIUM ION, D-galactose/methyl-galactoside binding periplasmic protein MglB, ...
Authors:Allert, M.J, Kumar, S, Wang, Y, Beese, L.S, Hellinga, H.W.
Deposit date:2023-01-25
Release date:2023-08-30
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching.
Commun Chem, 6, 2023
8FXU
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BU of 8fxu by Molmil
Thermoanaerobacter thermosaccharolyticum periplasmic Glucose-Binding Protein glucose complex: Badan conjugate attached at F17C
Descriptor: 2-bromo-1-[6-(dimethylamino)naphthalen-2-yl]ethan-1-one, CALCIUM ION, CHLORIDE ION, ...
Authors:Allert, M.J, Kumar, S, Beese, L.S, Hellinga, H.W.
Deposit date:2023-01-25
Release date:2023-08-30
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching.
Commun Chem, 6, 2023
2FJ2
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BU of 2fj2 by Molmil
Crystal Structure of Viral Macrophage Inflammatory Protein-II
Descriptor: Viral macrophage inflammatory protein-II
Authors:Li, Y, Liu, D, Cao, R, Kumar, S, Dong, C.Z, wilson, S.R, Gao, Y.G, Huang, Z.
Deposit date:2005-12-30
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of chemically synthesized vMIP-II.
Proteins, 67, 2007
4FOP
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BU of 4fop by Molmil
Crystal Structure of Peptidyl-tRNA hydrolase from Acinetobacter baumannii at 1.86 A resolution
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Kaushik, S, Kumar, S, Singh, N, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2012-06-21
Release date:2012-07-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The Mode of Inhibitor Binding to Peptidyl-tRNA Hydrolase: Binding Studies and Structure Determination of Unbound and Bound Peptidyl-tRNA Hydrolase from Acinetobacter baumannii
Plos One, 8, 2013
5Y2J
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BU of 5y2j by Molmil
Crystal structure of the oligomerization domain of NSP4 from rotavirus strain MF66
Descriptor: 1,2-ETHANEDIOL, NICKEL (II) ION, Nonstructural protein 4
Authors:Suguna, K, Kumar, S.
Deposit date:2017-07-26
Release date:2018-03-14
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:New tetrameric forms of the rotavirus NSP4 with antiparallel helices.
Arch. Virol., 163, 2018
5Y2E
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BU of 5y2e by Molmil
Crystal structure of the oligomerization domain of NSP4 from the rotavirus strain NCDV
Descriptor: Non-structural glycoprotein 4
Authors:Suguna, K, Kumar, S.
Deposit date:2017-07-25
Release date:2018-03-14
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:New tetrameric forms of the rotavirus NSP4 with antiparallel helices.
Arch. Virol., 163, 2018
5Y9R
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BU of 5y9r by Molmil
Crystal structure of the oligomerization domain of NSP4 from rotavirus strain MF66
Descriptor: 1,2-ETHANEDIOL, CADMIUM ION, NICKEL (II) ION, ...
Authors:Suguna, K, Kumar, S.
Deposit date:2017-08-28
Release date:2018-09-05
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:New tetrameric forms of the rotavirus NSP4 with antiparallel helices
To Be Published
5Y2H
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BU of 5y2h by Molmil
Crystal structure of the oligomerization domain of NSP4 from the rotavirus strain MF66
Descriptor: Nonstructural protein 4
Authors:Suguna, K, Kumar, S.
Deposit date:2017-07-25
Release date:2018-03-14
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:New tetrameric forms of the rotavirus NSP4 with antiparallel helices.
Arch. Virol., 163, 2018
5YQ8
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BU of 5yq8 by Molmil
Crystal structure of retroviral protease-like domain of Ddi1 from Leishmania major
Descriptor: DNA-damage inducible protein DDI1-like protein
Authors:Suguna, K, Kumar, S.
Deposit date:2017-11-06
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of the retroviral protease-like domain of a protozoal DNA damage-inducible 1 protein.
FEBS Open Bio, 8, 2018
2FHT
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BU of 2fht by Molmil
Crystal Structure of Viral Macrophage Inflammatory Protein-II
Descriptor: Viral macrophage inflammatory protein-II
Authors:Li, Y, Liu, D, Cao, R, Kumar, S, Dong, C.Z, wilson, S.R, Gao, Y.G, Huang, Z.
Deposit date:2005-12-27
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of chemically synthesized vMIP-II.
Proteins, 67, 2007
5YS4
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BU of 5ys4 by Molmil
Crystal structure of retroviral protease-like domain of Ddi1 from Leishmania major
Descriptor: DNA-damage inducible protein DDI1-like protein
Authors:Suguna, K, Kumar, S.
Deposit date:2017-11-13
Release date:2018-11-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the retroviral protease-like domain of a protozoal DNA damage-inducible 1 protein.
FEBS Open Bio, 8, 2018
8SR9
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BU of 8sr9 by Molmil
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium
Descriptor: CHOLESTEROL, MAGNESIUM ION, TRPM2 chanzyme
Authors:Huang, Y, Kumar, S, Lu, W, Du, J.
Deposit date:2023-05-05
Release date:2024-05-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 2024
8SR8
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BU of 8sr8 by Molmil
Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA (apo state)
Descriptor: CHOLESTEROL, TRPM2 chanzyme
Authors:Huang, Y, Kumar, S, Lu, W, Du, J.
Deposit date:2023-05-05
Release date:2024-05-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 2024
8SRA
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BU of 8sra by Molmil
Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium
Descriptor: CALCIUM ION, CHOLESTEROL, TRPM2 chanzyme
Authors:Huang, Y, Kumar, S, Lu, W, Du, J.
Deposit date:2023-05-05
Release date:2024-05-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 2024
8SRC
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BU of 8src by Molmil
Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium and ADP-ribose
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ...
Authors:Huang, Y, Kumar, S, Lu, W, Du, J.
Deposit date:2023-05-05
Release date:2024-05-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 2024
8SR7
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BU of 8sr7 by Molmil
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate
Descriptor: 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, CHOLESTEROL, ...
Authors:Huang, Y, Kumar, S, Lu, W, Du, J.
Deposit date:2023-05-05
Release date:2024-05-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (1.97 Å)
Cite:Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 2024
8SRB
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BU of 8srb by Molmil
Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA and ADP-ribose
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, TRPM2 chanzyme
Authors:Huang, Y, Kumar, S, Lu, W, Du, J.
Deposit date:2023-05-05
Release date:2024-05-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 2024
4LGX
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BU of 4lgx by Molmil
Structure of Chitinase D from Serratia proteamaculans revealed an unusually constrained substrate binding site
Descriptor: ACETATE ION, GLYCEROL, Glycoside hydrolase family 18
Authors:Madhuprakash, J, Singh, A, Kumar, S, Sinha, M, Kaur, P, Sharma, S, Podile, A.R, Singh, T.P.
Deposit date:2013-06-30
Release date:2013-10-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Inverse relationship between chitobiase and transglycosylation activities of chitinase-D from Serratia proteamaculans revealed by mutational and biophysical analyses.
Sci Rep, 5, 2015
8SRH
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BU of 8srh by Molmil
Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, open state
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ...
Authors:Huang, Y, Kumar, S, Lu, W, Du, J.
Deposit date:2023-05-05
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution
To Be Published
8SRI
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BU of 8sri by Molmil
Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, closed state
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ...
Authors:Huang, Y, Kumar, S, Lu, W, Du, J.
Deposit date:2023-05-05
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution
To Be Published
8SRE
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BU of 8sre by Molmil
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, closed state
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ...
Authors:Huang, Y, Kumar, S, Lu, W, Du, J.
Deposit date:2023-05-05
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution
To Be Published
8SRK
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BU of 8srk by Molmil
Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of Ca and ADP-ribose
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ...
Authors:Huang, Y, Kumar, S, Lu, W, Du, J.
Deposit date:2023-05-05
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (4.14 Å)
Cite:Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution
To Be Published
8SRJ
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BU of 8srj by Molmil
Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of EDTA, apo state
Descriptor: CHOLESTEROL, TRPM2 chanzyme
Authors:Huang, Y, Kumar, S, Lu, W, Du, J.
Deposit date:2023-05-05
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution
To Be Published

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