8TQS

Complex of human thrombin (S195A) bound to a bivalent inhibitor comprised of DNA Aptamer HD22 conjugated to Dabigatran with a linker.

Summary for 8TQS

• Entry DOI: 10.2210/pdb8tqs/pdb
• Descriptor: DNA (30-MER), Thrombin heavy chain, Prothrombin, ... (9 entities in total)
• Functional Keywords: human thrombin, dna aptamer, dabigatran, blood clotting
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 44937.87

Authors

Krishnaswamy, S.,Kumar, S. (deposition date: 2023-08-08, release date: 2024-05-01)

• Primary citation: Krishnaswamy, S.,Kumar, S.; Complex of human thrombin (S195A) bound to a bivalent inhibitor comprised of DNA Aptamer HD22 conjugated to Dabigatran with a linker.; Nat Commun, 2024

Experimental method

X-RAY DIFFRACTION (2.207 Å)