2JPN
 
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3RTR
 | | A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases | | Descriptor: | Cullin-1, E3 ubiquitin-protein ligase RBX1, ZINC ION | | Authors: | Calabrese, M.F, Scott, D.C, Duda, D.M, Grace, C.R, Kurinov, I, Kriwacki, R.W, Schulman, B.A. | | Deposit date: | 2011-05-03 | | Release date: | 2011-07-20 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.21 Å) | | Cite: | A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases.
Nat.Struct.Mol.Biol., 18, 2011
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4N8M
 | | Structural polymorphism in the N-terminal oligomerization domain of NPM1 | | Descriptor: | COBALT (II) ION, Nucleophosmin | | Authors: | Mitrea, D, Royappa, G, Buljan, M, Yun, M, Pytel, N, Satumba, J, Nourse, A, Park, C, Babu, M.M, White, S.W, Kriwacki, R.W. | | Deposit date: | 2013-10-17 | | Release date: | 2014-03-12 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.802 Å) | | Cite: | Structural polymorphism in the N-terminal oligomerization domain of NPM1.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2DCO
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1N17
 | | Structure and Dynamics of Thioguanine-modified Duplex DNA | | Descriptor: | 5'-D(*GP*CP*TP*AP*AP*GP*(S6G)P*AP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*TP*CP*CP*TP*TP*AP*GP*C)-3' | | Authors: | Somerville, L, Krynetski, E.Y, Krynetskaia, N.F, Beger, R.D, Zhang, W, Marhefka, C.A, Evans, W.E, Kriwacki, R.W. | | Deposit date: | 2002-10-16 | | Release date: | 2002-10-23 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Structure and dynamics of thioguanine-modified duplex DNA
J.Biol.Chem., 278, 2003
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1N14
 | | Structure and Dynamics of Thioguanine-modified Duplex DNA in Comparison with Unmodified DNA; Structure of Unmodified Duplex DNA | | Descriptor: | 5'-D(*GP*CP*TP*AP*AP*GP*GP*AP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*TP*CP*CP*TP*TP*AP*GP*C)-3' | | Authors: | Somerville, L, Krynetski, E.Y, Krynetskaia, N.F, Beger, R.D, Zhang, W, Marhefka, C.A, Evans, W.E, Kriwacki, R.W. | | Deposit date: | 2002-10-16 | | Release date: | 2002-10-23 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Structure and dynamics of thioguanine-modified duplex DNA
J.Biol.Chem., 278, 2003
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1W9R
 | | Solution Structure of Choline Binding Protein A, Domain R2, the Major Adhesin of Streptococcus pneumoniae | | Descriptor: | CHOLINE BINDING PROTEIN A | | Authors: | Luo, R, Mann, B, Lewis, W.S, Rowe, A, Heath, R, Stewart, M.L, Hamburger, A.E, Bjorkman, P.J, Sivakolundu, S, Lacy, E.R, Tuomanen, E, Kriwacki, R.W. | | Deposit date: | 2004-10-15 | | Release date: | 2005-02-22 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Choline Binding Protein A, the Major Adhesin of Streptococcus Pneumoniae
Embo J., 24, 2005
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1CQP
 | | CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION | | Descriptor: | ANTIGEN CD11A (P180), LOVASTATIN, MAGNESIUM ION | | Authors: | Kallen, J, Welzenbach, K, Ramage, P, Geyl, D, Kriwacki, R, Legge, G, Cottens, S, Weitz-Schmidt, G, Hommel, U. | | Deposit date: | 1999-08-10 | | Release date: | 2000-08-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain.
J.Mol.Biol., 292, 1999
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1DGQ
 | | NMR SOLUTION STRUCTURE OF THE INSERTED DOMAIN OF HUMAN LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1 | | Descriptor: | LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1 | | Authors: | Legge, G.B, Kriwacki, R.W, Chung, J, Hommel, U, Ramage, P, Case, D.A, Dyson, H.J, Wright, P.E. | | Deposit date: | 1999-11-24 | | Release date: | 2000-02-03 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of the inserted domain of human leukocyte function associated antigen-1.
J.Mol.Biol., 295, 2000
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6BF2
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1HN3
 | | SOLUTION STRUCTURE OF THE N-TERMINAL 37 AMINO ACIDS OF THE MOUSE ARF TUMOR SUPPRESSOR PROTEIN | | Descriptor: | P19 ARF PROTEIN | | Authors: | DiGiammarino, E.L, Filippov, I, Weber, J.D, Bothner, B, Kriwacki, R.W. | | Deposit date: | 2000-12-05 | | Release date: | 2001-12-05 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the p53 regulatory domain of the p19Arf tumor suppressor protein.
Biochemistry, 40, 2001
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1I1S
 | | SOLUTION STRUCTURE OF THE TRANSCRIPTIONAL ACTIVATION DOMAIN OF THE BACTERIOPHAGE T4 PROTEIN MOTA | | Descriptor: | MOTA | | Authors: | Li, N, Zhang, W, White, S.W, Kriwacki, R.W. | | Deposit date: | 2001-02-02 | | Release date: | 2001-02-14 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the transcriptional activation domain of the bacteriophage T4 protein, MotA.
Biochemistry, 40, 2001
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3O6B
 | | A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB) low resolution | | Descriptor: | Cell division control protein 53, Defective in cullin neddylation protein 1 | | Authors: | Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A. | | Deposit date: | 2010-07-28 | | Release date: | 2010-09-15 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
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3O2U
 | | S. cerevisiae Ubc12 | | Descriptor: | GLYCEROL, NEDD8-conjugating enzyme UBC12 | | Authors: | Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A. | | Deposit date: | 2010-07-22 | | Release date: | 2010-09-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.003 Å) | | Cite: | A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
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3O2P
 | | A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB) | | Descriptor: | Cell division control protein 53, Defective in cullin neddylation protein 1, GLYCEROL | | Authors: | Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A. | | Deposit date: | 2010-07-22 | | Release date: | 2010-09-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.233 Å) | | Cite: | A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
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1SP2
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1SP1
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2M5B
 | | The NMR structure of the BID-BAK complex | | Descriptor: | Bcl-2 homologous antagonist/killer, human_BID_BH3_SAHB | | Authors: | Moldoveanu, T, Grace, C.R, Kriwacki, R.W, Green, D.R. | | Deposit date: | 2013-02-19 | | Release date: | 2013-04-17 | | Last modified: | 2023-11-15 | | Method: | SOLUTION NMR | | Cite: | BID-induced structural changes in BAK promote apoptosis.
Nat.Struct.Mol.Biol., 20, 2013
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2M6N
 | | 3D solution structure of EMI1 (Early Mitotic Inhibitor 1) | | Descriptor: | F-box only protein 5, ZINC ION | | Authors: | Frye, J.J, Brown, N.G, Petzold, G, Watson, E.R, Royappa, G.R, Nourse, A, Jarvis, M, Kriwacki, R.W, Peters, J, Stark, H, Schulman, B.A. | | Deposit date: | 2013-04-06 | | Release date: | 2013-05-29 | | Last modified: | 2013-07-17 | | Method: | SOLUTION NMR | | Cite: | Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown.
Nat.Struct.Mol.Biol., 20, 2013
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2N0W
 | | Mdmx-SJ212 | | Descriptor: | 4-({(4S,5R)-4-(5-bromo-2-fluorophenyl)-5-(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, Protein Mdm4 | | Authors: | Grace, C.R, Kriwacki, R.W. | | Deposit date: | 2015-03-17 | | Release date: | 2016-01-27 | | Last modified: | 2016-05-04 | | Method: | SOLUTION NMR | | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
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2N06
 | | Mdmx-298 | | Descriptor: | 4-[[(4S,5R)-5-(4-chlorophenyl)-4-(3-methoxyphenyl)-2-(4-methoxy-2-propan-2-yloxy-phenyl)-4,5-dihydroimidazol-1-yl]carbonyl]piperazin-2-one, Protein Mdm4 | | Authors: | Grace, C.R, Kriwacki, R.W. | | Deposit date: | 2015-03-04 | | Release date: | 2016-01-27 | | Last modified: | 2019-11-06 | | Method: | SOLUTION NMR | | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
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2N14
 | | Mdmx-295 | | Descriptor: | 4-({(4S,5R)-4-(3-chlorophenyl)-5-(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, Protein Mdm4 | | Authors: | Grace, C.R, Kriwacki, R.W. | | Deposit date: | 2015-03-20 | | Release date: | 2016-01-27 | | Last modified: | 2016-05-04 | | Method: | SOLUTION NMR | | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
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2N0U
 | | Mdmx-057 | | Descriptor: | 4-[(4S,5R)-4-(3-chlorophenyl)-5-(4-chlorophenyl)-1-(3-oxidanylidenepiperazin-1-yl)carbonyl-4,5-dihydroimidazol-2-yl]-3-propan-2-yloxy-benzenecarbonitrile, Protein Mdm4 | | Authors: | Grace, C.R, Kriwacki, R.W. | | Deposit date: | 2015-03-17 | | Release date: | 2016-01-27 | | Last modified: | 2016-05-04 | | Method: | SOLUTION NMR | | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
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2ME9
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2M03
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