2N0W

Mdmx-SJ212

Summary for 2N0W

• Entry DOI: 10.2210/pdb2n0w/pdb
• Related: 2N06 2N0U 2N14
• NMR Information: BMRB: 25538
• Descriptor: Protein Mdm4, 4-({(4S,5R)-4-(5-bromo-2-fluorophenyl)-5-(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one (2 entities in total)
• Functional Keywords: mdmx, negative regulators of p53, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O15151
• Total number of polymer chains: 1
• Total formula weight: 10804.83

Authors

Grace, C.R.,Kriwacki, R.W. (deposition date: 2015-03-17, release date: 2016-01-27, Last modification date: 2016-05-04)

• Primary citation: Grace, C.R.,Ban, D.,Min, J.,Mayasundari, A.,Min, L.,Finch, K.E.,Griffiths, L.,Bharatham, N.,Bashford, D.,Kiplin Guy, R.,Dyer, M.A.,Kriwacki, R.W.; Monitoring Ligand-Induced Protein Ordering in Drug Discovery.; J.Mol.Biol., 428:1290-1303, 2016; PubMed: 26812210; DOI: 10.1016/j.jmb.2016.01.016

Experimental method

SOLUTION NMR