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PDB: 4 results

1N3Y
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Crystal structure of the alpha-X beta2 integrin I domain
Descriptor: Integrin alpha-X
Authors:Vorup-Jensen, T, Ostermeier, C, Shimaoka, M, Hommel, U, Springer, T.A.
Deposit date:2002-10-30
Release date:2003-02-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and allosteric regulation of the alpha X beta 2 integrin I domain.
Proc.Natl.Acad.Sci.USA, 100, 2003
1CQP
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CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION
Descriptor: ANTIGEN CD11A (P180), LOVASTATIN, MAGNESIUM ION
Authors:Kallen, J, Welzenbach, K, Ramage, P, Geyl, D, Kriwacki, R, Legge, G, Cottens, S, Weitz-Schmidt, G, Hommel, U.
Deposit date:1999-08-10
Release date:2000-08-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain.
J.Mol.Biol., 292, 1999
1DGQ
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NMR SOLUTION STRUCTURE OF THE INSERTED DOMAIN OF HUMAN LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1
Descriptor: LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1
Authors:Legge, G.B, Kriwacki, R.W, Chung, J, Hommel, U, Ramage, P, Case, D.A, Dyson, H.J, Wright, P.E.
Deposit date:1999-11-24
Release date:2000-02-03
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:NMR solution structure of the inserted domain of human leukocyte function associated antigen-1.
J.Mol.Biol., 295, 2000
1XUO
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X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution
Descriptor: (2R)-2-[3-ISOBUTYL-2,5-DIOXO-4-(QUINOLIN-3-YLMETHYL)-1,4-DIAZEPAN-1-YL]-N-METHYL-3-(2-NAPHTHYL)PROPANAMIDE, Integrin alpha-L, MAGNESIUM ION
Authors:Wattanasin, S, Kallen, J, Myers, S, Guo, Q, Sabio, M, Ehrhardt, C, Albert, R, Hommel, U, Weckbecker, G, Welzenbach, K.
Deposit date:2004-10-26
Release date:2005-10-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1
Bioorg.Med.Chem.Lett., 15, 2005

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