1CQP
CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION
Summary for 1CQP
Entry DOI | 10.2210/pdb1cqp/pdb |
Related | 1LFA 1ZON 1ZOO 1ZOP |
Descriptor | ANTIGEN CD11A (P180), MAGNESIUM ION, LOVASTATIN, ... (4 entities in total) |
Functional Keywords | rossmann fold, structural basis for lfa-1 inhibition, immune system |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: P20701 |
Total number of polymer chains | 2 |
Total formula weight | 42499.41 |
Authors | Kallen, J.,Welzenbach, K.,Ramage, P.,Geyl, D.,Kriwacki, R.,Legge, G.,Cottens, S.,Weitz-Schmidt, G.,Hommel, U. (deposition date: 1999-08-10, release date: 2000-08-07, Last modification date: 2024-02-07) |
Primary citation | Kallen, J.,Welzenbach, K.,Ramage, P.,Geyl, D.,Kriwacki, R.,Legge, G.,Cottens, S.,Weitz-Schmidt, G.,Hommel, U. Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain. J.Mol.Biol., 292:1-9, 1999 Cited by PubMed: 10493852DOI: 10.1006/jmbi.1999.3047 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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