1CQP
CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 310 |
| Chain | Residue |
| A | HOH3 |
| A | HOH17 |
| A | SER139 |
| A | SER141 |
| A | THR206 |
| A | ASP239 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 310 |
| Chain | Residue |
| B | HOH324 |
| B | SER139 |
| B | SER141 |
| B | ASP239 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 803 A 311 |
| Chain | Residue |
| A | LEU132 |
| A | ILE235 |
| A | TYR257 |
| A | LEU298 |
| A | LEU302 |
| B | VAL308 |
| B | ILE309 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 803 B 311 |
| Chain | Residue |
| A | VAL308 |
| A | ILE309 |
| B | LEU132 |
| B | TYR257 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 342 |
| Details | Domain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15728350","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26936951","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15728350","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26936951","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6R","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26936951","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5E6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
