1N14
Structure and Dynamics of Thioguanine-modified Duplex DNA in Comparison with Unmodified DNA; Structure of Unmodified Duplex DNA
Summary for 1N14
Entry DOI | 10.2210/pdb1n14/pdb |
Related | 1N17 |
Descriptor | 5'-D(*GP*CP*TP*AP*AP*GP*GP*AP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*TP*CP*CP*TP*TP*AP*GP*C)-3' (2 entities in total) |
Functional Keywords | mercaptopurine, thioguanine, anti-cancer therapy, dna |
Total number of polymer chains | 2 |
Total formula weight | 7943.19 |
Authors | Somerville, L.,Krynetski, E.Y.,Krynetskaia, N.F.,Beger, R.D.,Zhang, W.,Marhefka, C.A.,Evans, W.E.,Kriwacki, R.W. (deposition date: 2002-10-16, release date: 2002-10-23, Last modification date: 2022-02-23) |
Primary citation | Somerville, L.,Krynetski, E.Y.,Krynetskaia, N.F.,Beger, R.D.,Zhang, W.,Marhefka, C.A.,Evans, W.E.,Kriwacki, R.W. Structure and dynamics of thioguanine-modified duplex DNA J.Biol.Chem., 278:1005-1011, 2003 Cited by PubMed: 12401802DOI: 10.1074/jbc.M204243200 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report