2M5B

The NMR structure of the BID-BAK complex

Summary for 2M5B

• Entry DOI: 10.2210/pdb2m5b/pdb
• Related: 2BID 2IMT
• NMR Information: BMRB: 19045
• Descriptor: Bcl-2 homologous antagonist/killer, human_BID_BH3_SAHB (2 entities in total)
• Functional Keywords: bcl-2 family effector bak, bh3-only protein bid, effector direct activation, nmr solution structure of bid-bak complex, mitochondrial outer membrane premeabilization, apoptosis
• Biological source: Homo sapiens (human); More
• Cellular location: Mitochondrion membrane; Single-pass membrane protein (Potential): Q16611
• Total number of polymer chains: 2
• Total formula weight: 21483.20

Authors

Moldoveanu, T.,Grace, C.R.,Kriwacki, R.W.,Green, D.R. (deposition date: 2013-02-19, release date: 2013-04-17, Last modification date: 2023-11-15)

• Primary citation: Moldoveanu, T.,Grace, C.R.,Llambi, F.,Nourse, A.,Fitzgerald, P.,Gehring, K.,Kriwacki, R.W.,Green, D.R.; BID-induced structural changes in BAK promote apoptosis.; Nat.Struct.Mol.Biol., 20:589-597, 2013; PubMed: 23604079; DOI: 10.1038/nsmb.2563

Experimental method

SOLUTION NMR