Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 50 results
4OJC
DownloadVisualize
BU of 4ojc by Molmil
Crystal structure of the wild-type full-length trimeric ectodomain of the C. elegans fusion protein EFF-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EFF-1A, ...
Authors:Krey, T, Rey, F.A.
Deposit date:2014-01-21
Release date:2014-05-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structural basis of eukaryotic cell-cell fusion
Cell(Cambridge,Mass.), 157, 2014
4OJE
DownloadVisualize
BU of 4oje by Molmil
Crystal structure of a C-terminally truncated trimeric ectodomain of the C. elegans fusion protein EFF-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EFF-1A, ...
Authors:Krey, T, Rey, F.A.
Deposit date:2014-01-21
Release date:2014-05-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural basis of eukaryotic cell-cell fusion
Cell(Cambridge,Mass.), 157, 2014
4OJD
DownloadVisualize
BU of 4ojd by Molmil
Crystal structure of a C-terminally truncated trimeric ectodomain of the C. elegans fusion protein EFF-1 G260A/D321E/D322E mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, EFF-1A, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Krey, T, Rey, F.A.
Deposit date:2014-01-21
Release date:2014-05-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural basis of eukaryotic cell-cell fusion
Cell(Cambridge,Mass.), 157, 2014
4WHY
DownloadVisualize
BU of 4why by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P21 crystal form
Descriptor: Heavy chain of Fab fragment derived from neutralizing antibody 3/11, Light chain of Fab fragment derived from neutralizing antibody 3/11, epitope peptide
Authors:Krey, T, Rey, F.A.
Deposit date:2014-09-24
Release date:2014-12-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein e2 recognized by broadly neutralizing antibodies.
J.Virol., 89, 2015
4WHT
DownloadVisualize
BU of 4wht by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P1 crystal form
Descriptor: Epitope peptide, Heavy chain of the Fab fragment derived from neutralizing antibody 3/11, Light chain of the Fab fragment derived from neutralizing antibody 3/11
Authors:Krey, T, Rey, F.A.
Deposit date:2014-09-23
Release date:2014-12-17
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein e2 recognized by broadly neutralizing antibodies.
J.Virol., 89, 2015
4JVP
DownloadVisualize
BU of 4jvp by Molmil
Three dimensional structure of broadly neutralizing anti - Hepatitis C virus (HCV) glycoprotein E2 alpaca nanobody D03
Descriptor: Anti-HCV E2 alpaca nanobody D03, SULFATE ION
Authors:Krey, T, Rey, F.A.
Deposit date:2013-03-26
Release date:2013-04-24
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission.
Hepatology, 58, 2013
4JZN
DownloadVisualize
BU of 4jzn by Molmil
Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-1
Descriptor: Anti-HCV E2 Fab HC84-1 heavy chain, Anti-HCV E2 Fab HC84-1 light chain, Envelope glycoprotein E2, ...
Authors:Krey, T, Rey, F.A.
Deposit date:2013-04-03
Release date:2013-06-05
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.
Plos Pathog., 9, 2013
4JZO
DownloadVisualize
BU of 4jzo by Molmil
Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-27
Descriptor: Anti-HCV E2 Fab HC84-27 heavy chain, Anti-HCV E2 Fab HC84-27 light chain, Envelope glycoprotein E2
Authors:Krey, T, Rey, F.A.
Deposit date:2013-04-03
Release date:2013-06-05
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.
Plos Pathog., 9, 2013
4DW7
DownloadVisualize
BU of 4dw7 by Molmil
Crystal structure of an active-site mutant of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a CpU dinucleotide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-R(*CP*U)-3', ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DW4
DownloadVisualize
BU of 4dw4 by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 5'-UMP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DWC
DownloadVisualize
BU of 4dwc by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with Zn ions
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DVN
DownloadVisualize
BU of 4dvn by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 2'-UMP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-23
Release date:2012-05-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DW5
DownloadVisualize
BU of 4dw5 by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a non-cleavable CpU dinucleotide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DW3
DownloadVisualize
BU of 4dw3 by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 5'-CMP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYTIDINE-5'-MONOPHOSPHATE, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DWA
DownloadVisualize
BU of 4dwa by Molmil
Crystal structure of an active-site mutant of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a CpUpC trinucleotide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DVK
DownloadVisualize
BU of 4dvk by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 strain NCP-7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-23
Release date:2012-05-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DVL
DownloadVisualize
BU of 4dvl by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 2'-3'-cyclo-UMP
Descriptor: 1-[(2S,3aS,4S,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-2-oxidotetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]pyrimidine-2,4( 1H,3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-23
Release date:2012-05-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
5NPH
DownloadVisualize
BU of 5nph by Molmil
Structure of the Hepatitis C virus strain J4 glycoprotein E2 antigenic region 532-540 bound to the Fab fragment of the non-neutralizing antibody DAO5
Descriptor: Genome polyprotein, Heavy chain of Fab fragment derived from non-neutralizing antibody DAO5, Light chain of Fab fragment derived from non-neutralizing antibody DAO5
Authors:Vasiliauskaite, I, Rey, F.A, Krey, T.
Deposit date:2017-04-16
Release date:2017-05-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2.
MBio, 8, 2017
8PHI
DownloadVisualize
BU of 8phi by Molmil
Crystal structure of prefusion-stabilized RSV F Variant DS-Cav1 in complex with Lonafarnib
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE, CALCIUM ION, ...
Authors:Rajak, M, Krey, T.
Deposit date:2023-06-19
Release date:2024-02-21
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.289 Å)
Cite:Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor.
Nat Commun, 15, 2024
8PMX
DownloadVisualize
BU of 8pmx by Molmil
rat HEV P domain in complex with glycan-sensitive nAb p60.12
Descriptor: Fab p60.12-HC, Fab p60.12-LC, Pro-secreted protein ORF2
Authors:Ssebyatika, G, Krey, T.
Deposit date:2023-06-29
Release date:2024-07-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.922 Å)
Cite:A novel class of broadly neutralizing hepatitis E virus-specific human antibodies
To Be Published
8PMW
DownloadVisualize
BU of 8pmw by Molmil
HEV gt3 P domain in complex with glycan-sensitive nAb p60.1
Descriptor: ACETATE ION, Capsid protein, SULFATE ION, ...
Authors:Ssebyatika, G, Krey, T.
Deposit date:2023-06-29
Release date:2024-07-10
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:A novel class of broadly neutralizing hepatitis E virus-specific human antibodies
To Be Published
8PN0
DownloadVisualize
BU of 8pn0 by Molmil
HEV gt3 P domain in complex with glycan-sensitive nAb p60.12
Descriptor: Capsid protein, Fab_p60.12-HC, Fab_p60.12-LC
Authors:Ssebyatika, G, Krey, T.
Deposit date:2023-06-29
Release date:2024-07-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.072 Å)
Cite:A novel class of broadly neutralizing hepatitis E virus-specific human antibodies
To Be Published
8PMY
DownloadVisualize
BU of 8pmy by Molmil
HEV gt3 P domain in complex with glycan-insensitive nAb p60.15
Descriptor: Capsid protein, ZINC ION, scFv_p60.15
Authors:Ssebyatika, G, Krey, T.
Deposit date:2023-06-29
Release date:2024-07-10
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:A novel class of broadly neutralizing hepatitis E virus-specific human antibodies
To Be Published
8PMZ
DownloadVisualize
BU of 8pmz by Molmil
HEV gt3 P domain in complex with glycan-insensitive nAb p61.15
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pro-secreted protein ORF2, scFv_p61.15
Authors:Ssebyatika, G, Krey, T.
Deposit date:2023-06-29
Release date:2024-07-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.912 Å)
Cite:A novel class of broadly neutralizing hepatitis E virus-specific human antibodies
To Be Published
6S3D
DownloadVisualize
BU of 6s3d by Molmil
Structure of D25 Fab in complex with scaffold S0_2.126
Descriptor: Heavy Chain, Light Chain, S0_2.126
Authors:Cramer, J.T, Krey, T.
Deposit date:2019-06-25
Release date:2020-04-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:De novo protein design enables the precise induction of RSV-neutralizing antibodies.
Science, 368, 2020

 

12>

234136

PDB entries from 2025-04-02

PDB statisticsPDBj update infoContact PDBjnumon