7T51
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![BU of 7t51 by Molmil](/molmil-images/mine/7t51) | Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in molybdate-bound form | 分子名称: | AMMONIUM ION, GLYCEROL, MOLYBDATE ION, ... | 著者 | Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B. | 登録日 | 2021-12-11 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis. Front Microbiol, 13, 2022
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6W0S
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![BU of 6w0s by Molmil](/molmil-images/mine/6w0s) | Crystal structure of substrate free cytochrome P450 NasF5053 from Streptomyces sp. NRRL F-5053 | 分子名称: | BROMIDE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Luo, Z, Jia, X, Sun, C, Qu, X, Kobe, B. | 登録日 | 2020-03-02 | 公開日 | 2020-11-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines. Nat Commun, 11, 2020
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4MZ6
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![BU of 4mz6 by Molmil](/molmil-images/mine/4mz6) | Structure of importin-alpha: dUTPase S11E NLS mutant complex | 分子名称: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1 | 著者 | Marfori, M, Rona, G, Vertessy, B.G, Kobe, B. | 登録日 | 2013-09-29 | 公開日 | 2013-11-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights. Acta Crystallogr.,Sect.D, 69, 2013
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4MZ5
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![BU of 4mz5 by Molmil](/molmil-images/mine/4mz5) | Structure of importin-alpha: dUTPase NLS complex | 分子名称: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1 | 著者 | Marfori, M, Rona, G, Vertessy, B.G, Kobe, B. | 登録日 | 2013-09-29 | 公開日 | 2013-11-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights. Acta Crystallogr.,Sect.D, 69, 2013
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3OZI
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![BU of 3ozi by Molmil](/molmil-images/mine/3ozi) | Crystal structure of the TIR domain from the flax disease resistance protein L6 | 分子名称: | COBALT (II) ION, L6tr | 著者 | Ve, T, Bernoux, M, Williams, S, Valkov, E, Warren, C, Hatters, D, Ellis, J.G, Dodds, P.N, Kobe, B. | 登録日 | 2010-09-25 | 公開日 | 2011-04-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation. Cell Host Microbe, 9, 2011
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5D90
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![BU of 5d90 by Molmil](/molmil-images/mine/5d90) | |
2Y92
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![BU of 2y92 by Molmil](/molmil-images/mine/2y92) | Crystal structure of MAL adaptor protein | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, TOLL/INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN, | 著者 | Valkov, E, Stamp, A, Martin, J.L, Kobe, B. | 登録日 | 2011-02-11 | 公開日 | 2011-09-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Crystal Structure of Toll-Like Receptor Adaptor Mal/Tirap Reveals the Molecular Basis for Signal Transduction and Disease Protection. Proc.Natl.Acad.Sci.USA, 108, 2011
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3ND2
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7T4Z
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![BU of 7t4z by Molmil](/molmil-images/mine/7t4z) | Crystal structure of the molybdate-binding periplasmic protein ModA from the bacteria Pseudomonsa aeruginosa in ligand-free form | 分子名称: | AMMONIUM ION, GLYCEROL, Molybdate-binding periplasmic protein, ... | 著者 | Ngu, D.H.Y, Luo, Z, Lim, B.Y.J, Kobe, B. | 登録日 | 2021-12-10 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis. Front Microbiol, 13, 2022
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1Q1S
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![BU of 1q1s by Molmil](/molmil-images/mine/1q1s) | Mouse Importin alpha- phosphorylated SV40 CN peptide complex | 分子名称: | Importin alpha-2 subunit, Large T antigen | 著者 | Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. | 登録日 | 2003-07-22 | 公開日 | 2004-03-30 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Biochem.J., 375, 2003
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7JJ8
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![BU of 7jj8 by Molmil](/molmil-images/mine/7jj8) | Crystal structure of the Zn(II)-bound ZnuA-like domain of Streptococcus pneumoniae AdcA | 分子名称: | ZINC ION, Zinc-binding lipoprotein AdcA | 著者 | Luo, Z, More, J.R, Kobe, B, McDevitt, C.A. | 登録日 | 2020-07-24 | 公開日 | 2020-12-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA. Mbio, 12, 2021
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1Q1T
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![BU of 1q1t by Molmil](/molmil-images/mine/1q1t) | Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex | 分子名称: | Importin alpha-2 subunit, Large T antigen | 著者 | Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. | 登録日 | 2003-07-22 | 公開日 | 2004-03-30 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Biochem.J., 375, 2003
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3UKW
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![BU of 3ukw by Molmil](/molmil-images/mine/3ukw) | Mouse importin alpha: Bimax1 peptide complex | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bimax1 peptide, Importin subunit alpha-2 | 著者 | Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. | 登録日 | 2011-11-10 | 公開日 | 2012-10-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
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5TEC
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![BU of 5tec by Molmil](/molmil-images/mine/5tec) | Crystal structure of the TIR domain from the Arabidopsis thaliana NLR protein SNC1 | 分子名称: | Protein SUPPRESSOR OF npr1-1, CONSTITUTIVE 1 | 著者 | Zhang, X, Bentham, A, Ve, T, Williams, S.J, Kobe, B. | 登録日 | 2016-09-20 | 公開日 | 2017-02-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Multiple functional self-association interfaces in plant TIR domains. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2YNR
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![BU of 2ynr by Molmil](/molmil-images/mine/2ynr) | mImp_alphadIBB_B54NLS | 分子名称: | B54NLS, IMPORTIN SUBUNIT ALPHA | 著者 | Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. | 登録日 | 2012-10-18 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
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5E01
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![BU of 5e01 by Molmil](/molmil-images/mine/5e01) | Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to palyndromic promoter DNA | 分子名称: | 5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*GP*CP*AP*CP*TP*CP*TP*AP*AP*G)-3', Uncharacterized HTH-type transcriptional regulator HI_0186 | 著者 | Counago, R.M, Chang, C.W, Chen, N.H, Djoko, K.Y, McEwan, A.G, Kobe, B. | 登録日 | 2015-09-26 | 公開日 | 2016-06-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region. Nucleic Acids Res., 44, 2016
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7UWG
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![BU of 7uwg by Molmil](/molmil-images/mine/7uwg) | The crystal structure of the TIR domain-containing protein from Acinetobacter baumannii (AbTir) | 分子名称: | HEXAETHYLENE GLYCOL, Molecular chaperone Tir, SULFATE ION | 著者 | Manik, M.K, Nanson, J.D, Ve, T, Kobe, B. | 登録日 | 2022-05-03 | 公開日 | 2022-09-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling. Science, 377, 2022
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7UXU
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![BU of 7uxu by Molmil](/molmil-images/mine/7uxu) | CryoEM structure of the TIR domain from AbTir in complex with 3AD | 分子名称: | Molecular chaperone Tir, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(8-azanylisoquinolin-2-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | 著者 | Li, S, Nanson, J.D, Manik, M.K, Gu, W, Landsberg, M.J, Ve, T, Kobe, B. | 登録日 | 2022-05-06 | 公開日 | 2022-09-07 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling. Science, 377, 2022
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1WNH
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![BU of 1wnh by Molmil](/molmil-images/mine/1wnh) | Crystal structure of mouse Latexin (tissue carboxypeptidase inhibitor) | 分子名称: | Latexin | 著者 | Aagaard, A, Listwan, P, Cowieson, N, Huber, T, Ravasi, T, Wells, C.A, Flanagan, J.U, Hume, D.A, Kobe, B, Martin, J.L. | 登録日 | 2004-08-04 | 公開日 | 2005-02-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | An Inflammatory Role for the Mammalian Carboxypeptidase Inhibitor Latexin: Relationship to Cystatins and the Tumor Suppressor TIG1 Structure, 13, 2005
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7SHJ
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8V6Q
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![BU of 8v6q by Molmil](/molmil-images/mine/8v6q) | Crystal structure of EcThsA in ligand-free state | 分子名称: | Thoeris protein ThsA Macro domain-containing protein | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, V, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | 登録日 | 2023-12-02 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems. Sci Adv, 10, 2024
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8V6S
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![BU of 8v6s by Molmil](/molmil-images/mine/8v6s) | Crystal structure of PcThsA in complex with Imidazole Adenine Dinucleotide | 分子名称: | Thoeris protein ThsA Macro domain-containing protein, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-imidazol-1-yl-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, E, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | 登録日 | 2023-12-02 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems. Sci Adv, 10, 2024
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8V6T
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![BU of 8v6t by Molmil](/molmil-images/mine/8v6t) | Crystal structure of EcThsB2 | 分子名称: | BROMIDE ION, Molecular chaperone Tir | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, E, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | 登録日 | 2023-12-02 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems. Sci Adv, 10, 2024
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8V6R
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![BU of 8v6r by Molmil](/molmil-images/mine/8v6r) | Crystal structure of EcThsA in complex with ADPR | 分子名称: | Thoeris protein ThsA Macro domain-containing protein, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, E, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | 登録日 | 2023-12-02 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems. Sci Adv, 10, 2024
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6VZA
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![BU of 6vza by Molmil](/molmil-images/mine/6vza) | Crystal structure of cytochrome P450 NasF5053 Q65I-A86G mutant variant from Streptomyces sp. NRRL F-5053 in the cyclo-L-Trp-L-Pro-bound state | 分子名称: | (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, CALCIUM ION, CHLORIDE ION, ... | 著者 | Luo, Z, Jia, X, Sun, C, Qu, X, Kobe, B. | 登録日 | 2020-02-28 | 公開日 | 2020-11-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines. Nat Commun, 11, 2020
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