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PDB: 56 件
3RYH
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BU of 3ryh by Molmil
GMPCPP-Tubulin: RB3 Stathmin-like domain complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Nawrotek, A, Knossow, M, Gigant, B.
登録日2011-05-11
公開日2011-10-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin.
J.Mol.Biol., 412, 2011
3RYF
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GTP-Tubulin: RB3 Stathmin-like domain complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ...
著者Nawrotek, A, Knossow, M, Gigant, B.
登録日2011-05-11
公開日2011-10-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin.
J.Mol.Biol., 412, 2011
1SQK
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CRYSTAL STRUCTURE OF CIBOULOT IN COMPLEX WITH SKELETAL ACTIN
分子名称: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hertzog, M, Van Heijenoort, C, Didry, D, Gaudier, M, Gigant, B, Coutant, J, Didelot, G, Preat, T, Knossow, M, Guittet, E, Carlier, M.F.
登録日2004-03-19
公開日2004-06-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The beta-Thymosin/WH2 Domain; Structural Basis for the Switch from Inhibition to Promotion of Actin Assembly
Cell(Cambridge,Mass.), 117, 2004
1KN2
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BU of 1kn2 by Molmil
CATALYTIC ANTIBODY D2.3 COMPLEX
分子名称: IG ANTIBODY D2.3 (HEAVY CHAIN), IG ANTIBODY D2.3 (LIGHT CHAIN), PARA-NITROPHENYL PHOSPHONOBUTANOYL L-ALANINE, ...
著者Gigant, B, Knossow, M.
登録日2001-12-18
公開日2002-03-13
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Remarkable remote chiral recognition in a reaction mediated by a catalytic antibody.
J.Am.Chem.Soc., 124, 2002
1KN4
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CATALYTIC ANTIBODY D2.3 COMPLEX
分子名称: IG ANTIBODY D2.3 (HEAVY CHAIN), IG ANTIBODY D2.3 (LIGHT CHAIN), PARA-NITROPHENYL PHOSPHONOBUTANOYL D-ALANINE, ...
著者Gigant, B, Knossow, M.
登録日2001-12-18
公開日2002-03-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Remarkable remote chiral recognition in a reaction mediated by a catalytic antibody.
J.Am.Chem.Soc., 124, 2002
4EB6
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Tubulin-Vinblastine: Stathmin-like complex
分子名称: (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ranaivoson, F.M, Gigant, B, Knossow, M.
登録日2012-03-23
公開日2012-08-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.47 Å)
主引用文献Structural plasticity of tubulin assembly probed by vinca-domain ligands.
Acta Crystallogr.,Sect.D, 68, 2012
3HKB
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Tubulin: RB3 Stathmin-like domain complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M.
登録日2009-05-23
公開日2009-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
Proc.Natl.Acad.Sci.USA, 106, 2009
4F6R
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BU of 4f6r by Molmil
Tubulin:Stathmin-like domain complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Designed ankyrin repeat protein (DARPIN) D2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Gigant, B, Mignot, I, Knossow, M.
登録日2012-05-15
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Design and characterization of modular scaffolds for tubulin assembly.
J.Biol.Chem., 287, 2012
1EO8
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INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (HEAVY CHAIN), ...
著者Fleury, D, Gigant, B, Daniels, R.S, Skehel, J.J, Knossow, M, Bizebard, T.
登録日2000-03-22
公開日2000-04-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural evidence for recognition of a single epitope by two distinct antibodies.
Proteins, 40, 2000
4F61
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Tubulin:Stathmin-like domain complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Gigant, B, Mignot, I, Knossow, M.
登録日2012-05-14
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.17 Å)
主引用文献Design and characterization of modular scaffolds for tubulin assembly.
J.Biol.Chem., 287, 2012
1SA1
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BU of 1sa1 by Molmil
Tubulin-podophyllotoxin: stathmin-like domain complex
分子名称: 9-HYDROXY-5-(3,4,5-TRIMETHOXYPHENYL)-5,8,8A,9-TETRAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-6(5AH)-ONE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ravelli, R.B, Gigant, B, Curmi, P.A, Jourdain, I, Lachkar, S, Sobel, A, Knossow, M.
登録日2004-02-06
公開日2004-03-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.
Nature, 428, 2004
1SA0
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TUBULIN-COLCHICINE: STATHMIN-LIKE DOMAIN COMPLEX
分子名称: 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ravelli, R.B, Gigant, B, Curmi, P.A, Jourdain, I, Lachkar, S, Sobel, A, Knossow, M.
登録日2004-02-06
公開日2004-03-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.58 Å)
主引用文献Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.
Nature, 428, 2004
4HNA
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BU of 4hna by Molmil
Kinesin motor domain in the ADP-MG-ALFX state in complex with tubulin and a DARPIN
分子名称: ADENOSINE-5'-DIPHOSPHATE, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Gigant, B, Knossow, M.
登録日2012-10-19
公開日2013-06-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structure of a kinesin-tubulin complex and implications for kinesin motility.
Nat.Struct.Mol.Biol., 20, 2013
4DUI
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BU of 4dui by Molmil
DARPIN D1 binding to tubulin beta chain (not in complex)
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1
著者Pecqueur, L, Duellberg, C, Dreier, B, Wang, Q, Jiang, C, Pluckthun, A, Surrey, T, Gigant, B, Knossow, M.
登録日2012-02-22
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献An Anti-Tubulin Darpin Caps the Microtubule Plus-End
To be Published
1TQC
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BU of 1tqc by Molmil
Ovine recombinant PrP(114-234), ARR variant in complex with the VRQ14 Fab fragment (IgG2a)
分子名称: VRQ14 Fab Heavy chain, VRQ14 Fab light chain, prion protein
著者Eghiaian, F, Grosclaude, J, Lesceu, S, Debey, P, Doublet, B, Treguer, E, Rezaei, H, Knossow, M.
登録日2004-06-17
公開日2004-07-06
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Insight into the PrPC-->PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants
Proc.Natl.Acad.Sci.USA, 101, 2004
1TPX
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BU of 1tpx by Molmil
Ovine recombinant PrP(114-234), ARQ variant in complex with the Fab of the VRQ14 antibody
分子名称: major prion protein, the VRQ14 Fab
著者Eghiaian, F, Grosclaude, J, Lesceu, S, Debey, P, Doublet, B, Treguer, E, Rezaei, H, Knossow, M.
登録日2004-06-16
公開日2004-07-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Insight into the PrPC -> PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants.
Proc.Natl.Acad.Sci.USA, 101, 2004
1TQB
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BU of 1tqb by Molmil
Ovine recombinant PrP(114-234), VRQ variant in complex with the Fab of the VRQ14 antibody
分子名称: VRQ14 Fab Heavy chain, VRQ14 Fab light chain, prion protein
著者Eghiaian, F, Grosclaude, J, Debey, P, Doublet, B, Treguer, E, Rezaei, H, Knossow, M.
登録日2004-06-17
公開日2004-07-06
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Insight into the PrPC-->PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants
Proc.Natl.Acad.Sci.USA, 101, 2004
1YEG
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BU of 1yeg by Molmil
STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH REACTION PRODUCT
分子名称: ACETATE ION, IGG2A FAB FRAGMENT, PARANITROBENZYL ALCOHOL, ...
著者Gigant, B, Knossow, M.
登録日1997-05-29
公開日1997-12-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc.Natl.Acad.Sci.USA, 94, 1997
1Z2B
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BU of 1z2b by Molmil
Tubulin-colchicine-vinblastine: stathmin-like domain complex
分子名称: (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, ...
著者Gigant, B, Wang, C, Ravelli, R.B.G, Roussi, F, Steinmetz, M.O, Curmi, P.A, Sobel, A, Knossow, M.
登録日2005-03-08
公開日2005-05-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structural basis for the regulation of tubulin by vinblastine.
Nature, 435, 2005
1CT8
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BU of 1ct8 by Molmil
CATALYTIC ANTIBODY 7C8 COMPLEX
分子名称: 7C8 FAB FRAGMENT; LONG CHAIN, 7C8 FAB FRAGMENT; SHORT CHAIN, SULFATE ION, ...
著者Gigant, B, Tsumuraya, T, Fujii, I, Knossow, M.
登録日1999-08-20
公開日1999-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Diverse structural solutions to catalysis in a family of antibodies.
Structure Fold.Des., 7, 1999
1FFX
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BU of 1ffx by Molmil
TUBULIN:STATHMIN-LIKE DOMAIN COMPLEX
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, PROTEIN (STATHMIN-LIKE DOMAIN OF RB3), ...
著者Gigant, B, Martin-Barbey, C, Knossow, M.
登録日2000-07-26
公開日2000-09-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献The 4 A X-ray structure of a tubulin:stathmin-like domain complex.
Cell(Cambridge,Mass.), 102, 2000
1YEF
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BU of 1yef by Molmil
STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH SUBSTRATE ANALOGUE
分子名称: IGG2A FAB FRAGMENT, PARA-NITROBENZYL GLUTARYL GLYCINIC ACID, ZINC ION
著者Gigant, B, Knossow, M.
登録日1997-05-29
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc.Natl.Acad.Sci.USA, 94, 1997
1GIG
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BU of 1gig by Molmil
REFINED THREE-DIMENSIONAL STRUCTURE OF THE FAB FRAGMENT OF A MURINE IGG1, LAMBDA ANTIBODY
分子名称: IGG1-KAPPA HC19 FAB (HEAVY CHAIN), IGG1-KAPPA HC19 FAB (LIGHT CHAIN)
著者Bizebard, T, Knossow, M.
登録日1993-01-20
公開日1994-04-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined three-dimensional structure of the Fab fragment of a murine IgGl,lambda antibody.
Acta Crystallogr.,Sect.D, 50, 1994
1F3D
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CATALYTIC ANTIBODY 4B2 IN COMPLEX WITH ITS AMIDINIUM HAPTEN.
分子名称: 2-(4-AMINOBENZYLAMINO)-3,4,5,6-TETRAHYDROPYRIDINIUM, CATALYTIC ANTIBODY 4B2, SULFATE ION
著者Golinelli-Pimpaneau, B, Goncalves, O, Dintinger, T, Blanchard, D, Knossow, M, Tellier, C.
登録日2000-06-02
公開日2000-09-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural evidence for a programmed general base in the active site of a catalytic antibody.
Proc.Natl.Acad.Sci.USA, 97, 2000
1YEC
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STRUCTURE OF A CATALYTIC ANTIBODY IGG2A FAB FRAGMENT (D2.3)
分子名称: 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE, IGG2A FAB FRAGMENT (D2.3), ZINC ION
著者Golinelli-Pimpaneau, B, Knossow, M.
登録日1997-04-15
公開日1997-10-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural convergence in the active sites of a family of catalytic antibodies.
Science, 275, 1997

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