1Z2B

Tubulin-colchicine-vinblastine: stathmin-like domain complex

Summary for 1Z2B

• Entry DOI: 10.2210/pdb1z2b/pdb
• Related: 1SA0 1SA1
• Descriptor: Tubulin alpha chain, Tubulin beta chain, RB3 STATHMIN-LIKE DOMAIN 4, ... (8 entities in total)
• Functional Keywords: alpha-tubulin, beta-tubulin, colchicine, gtpase, microtubule, stathmin, tubulin, vinblastine, cell cycle
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 5
• Total formula weight: 220138.10

Authors

Gigant, B.,Wang, C.,Ravelli, R.B.G.,Roussi, F.,Steinmetz, M.O.,Curmi, P.A.,Sobel, A.,Knossow, M. (deposition date: 2005-03-08, release date: 2005-05-31, Last modification date: 2023-08-23)

• Primary citation: Gigant, B.,Wang, C.,Ravelli, R.B.,Roussi, F.,Steinmetz, M.O.,Curmi, P.A.,Sobel, A.,Knossow, M.; Structural basis for the regulation of tubulin by vinblastine.; Nature, 435:519-522, 2005; PubMed: 15917812; DOI: 10.1038/nature03566

Experimental method

X-RAY DIFFRACTION (4.1 Å)