Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 15 results

7Z68
DownloadVisualize
BU of 7z68 by Molmil
Pseudomonas aeruginosa Elastase in complex with a Thiol based inhibitor (R-and S-configured)
Descriptor: (2~{R})-~{N}-[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanylphenyl]-3-phenyl-2-sulfanyl-propanamide, CALCIUM ION, GLYCEROL, ...
Authors:Klein, A, Hirsch, A.
Deposit date:2022-03-11
Release date:2023-09-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Dual inhibitors of Pseudomonas aeruginosa virulence factors LecA and LasB
To Be Published
5EW5
DownloadVisualize
BU of 5ew5 by Molmil
Crystal Structure of Colicin E9 In Complex with Its Immunity Protein Im9
Descriptor: Colicin-E9, Colicin-E9 immunity protein
Authors:Klein, A, Wojdyla, J.A, Kleanthous, C.
Deposit date:2015-11-20
Release date:2016-07-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and biophysical analysis of nuclease protein antibiotics.
Biochem.J., 473, 2016
6DGK
DownloadVisualize
BU of 6dgk by Molmil
Crystal Structure of the Non-Structural Protein 1 (NS1) effector domain W187A mutant from the A/Brevig Mission/1/1918 (H1N1) strain of Influenza A Virus
Descriptor: Non-structural protein 1
Authors:Kleinpeter, A.B, Green, T.J, Petit, C.M.
Deposit date:2018-05-17
Release date:2018-08-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compounds.
J. Biol. Chem., 293, 2018
1N5Z
DownloadVisualize
BU of 1n5z by Molmil
Complex structure of Pex13p SH3 domain with a peptide of Pex14p
Descriptor: 14-mer peptide from Peroxisomal membrane protein PEX14, Peroxisomal membrane protein PAS20
Authors:Douangamath, A, Filipp, F.V, Klein, A.T.J, Barnett, P, Zou, P, Voorn-Brouwer, T, Vega, M.C, Mayans, O.M, Sattler, M, Distel, B, Wilmanns, M.
Deposit date:2002-11-08
Release date:2002-12-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Topography for Independent Binding of alpha-Helical and PPII-Helical Ligands to a Peroxisomal SH3 Domain
MOL.CELL, 10, 2002
8RW3
DownloadVisualize
BU of 8rw3 by Molmil
Crystal Structure of Agd31B, alpha-transglucosylase, complexed with a non-covalent 1,2- Cyclophellitol aziridine
Descriptor: (1~{S},2~{R},3~{R},4~{R},6~{S})-4-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3-diol, 1,2-ETHANEDIOL, OXALATE ION, ...
Authors:Moran, E, Davies, G, Ofamn, T, Heming, J, Nin-Hill, A, Kullmer, F, Steneker, R, Klein, A, Bennett, M, Ruijgrok, G, Kok, K, Aerts, J, Van der Marel, G, Rovira, C, Artola, M, Codee, J, Overkleeft, H.
Deposit date:2024-02-02
Release date:2024-05-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational and Electronic Variations in 1,2- and 1,5a-Cyclophellitols and their Impact on Retaining alpha-Glucosidase Inhibition.
Chemistry, 30, 2024
4JML
DownloadVisualize
BU of 4jml by Molmil
Crystal structure of the TolB(P201C)-ColicinE9 TBE peptide(A33C) complex.
Descriptor: CALCIUM ION, Colicin-E9, Protein TolB
Authors:Wojdyla, J.A, Klein, A, Kleanthous, C.
Deposit date:2013-03-14
Release date:2013-07-17
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Intrinsically disordered protein threads through the bacterial outer-membrane porin OmpF.
Science, 340, 2013
6OS2
DownloadVisualize
BU of 6os2 by Molmil
Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV026
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
Authors:Wingler, L.M, Staus, D.P, Skiba, M.A, McMahon, C, Kleinhenz, A.L.W, Lefkowitz, R.J, Kruse, A.C.
Deposit date:2019-05-01
Release date:2020-02-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
Science, 367, 2020
7R7P
DownloadVisualize
BU of 7r7p by Molmil
Immature HIV-1 CACTD-SP1 lattice with Bevirimat (BVM) and Inositol hexakisphosphate (IP6)
Descriptor: 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
Authors:Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T.
Deposit date:2021-06-25
Release date:2023-02-15
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Structural basis of HIV-1 maturation inhibitor binding and activity.
Nat Commun, 14, 2023
7R7Q
DownloadVisualize
BU of 7r7q by Molmil
Immature HIV-1 CACTD-SP1 lattice with Inositol hexakisphosphate (IP6)
Descriptor: Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
Authors:Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T.
Deposit date:2021-06-25
Release date:2023-02-15
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Structural basis of HIV-1 maturation inhibitor binding and activity.
Nat Commun, 14, 2023
6U1N
DownloadVisualize
BU of 6u1n by Molmil
GPCR-Beta arrestin structure in lipid bilayer
Descriptor: 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, Beta-arrestin-1, Fab30 heavy chain, ...
Authors:Staus, D.P, Hu, H, Robertson, M.J, Kleinhenz, A.L.W, Wingler, L.M, Capel, W.D, Latorraca, N.R, Lefkowitz, R.J, Skiniotis, G.
Deposit date:2019-08-16
Release date:2020-02-26
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of the M2 muscarinic receptor-beta-arrestin complex in a lipid nanodisc.
Nature, 579, 2020
4KNB
DownloadVisualize
BU of 4knb by Molmil
C-Met in complex with OSI ligand
Descriptor: 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine, GAMMA-BUTYROLACTONE, Hepatocyte growth factor receptor
Authors:Wang, J, Steinig, A.G, Li, A.H, Chen, X, Dong, H, Ferraro, C, Jin, M, Kadalbajoo, M, Kleinberg, A, Stolz, K.M, Tavares-Greco, P.A, Wang, T, Albertella, M.R, Peng, Y, Crew, L, Kahler, J.
Deposit date:2013-05-09
Release date:2014-04-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases.
Bioorg.Med.Chem.Lett., 23, 2013
2N74
DownloadVisualize
BU of 2n74 by Molmil
Solution Structure of the RNA-Binding domain of non-structural protein 1 from the 1918 H1N1 influenza virus
Descriptor: Non-structural protein 1
Authors:Jureka, A.S, Kleinpeter, A.B, Cornilescu, G, Cornilescu, C.C, Schwieters, C.D, Petit, C.M.
Deposit date:2015-09-03
Release date:2015-09-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis for a Novel Interaction between the NS1 Protein Derived from the 1918 Influenza Virus and RIG-I.
Structure, 23, 2015
6OS0
DownloadVisualize
BU of 6os0 by Molmil
Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to angiotensin II
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen, CHLORIDE ION, ...
Authors:Wingler, L.M, Staus, D.P, Skiba, M.A, McMahon, C, Kleinhenz, A.L.W, Lefkowitz, R.J, Kruse, A.C.
Deposit date:2019-05-01
Release date:2020-02-19
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
Science, 367, 2020
6OS1
DownloadVisualize
BU of 6os1 by Molmil
Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV023
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Nanobody Nb.AT110i1_le, ...
Authors:Wingler, L.M, Staus, D.P, Skiba, M.A, McMahon, C, Kleinhenz, A.L.W, Lefkowitz, R.J, Kruse, A.C.
Deposit date:2019-05-01
Release date:2020-02-19
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.794 Å)
Cite:Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
Science, 367, 2020
4ID7
DownloadVisualize
BU of 4id7 by Molmil
ACK1 kinase in complex with the inhibitor cis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol
Descriptor: Activated CDC42 kinase 1, SULFATE ION, cis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol
Authors:Jin, M, Wang, J, Kleinberg, A, Kadalbajoo, M, Siu, K, Cooke, A, Bittner, M, Yao, Y, Thelemann, A, Ji, Q, Bhagwat, S, Crew, A.P, Pachter, J, Epstein, D, Mulvihill, M.J.
Deposit date:2012-12-11
Release date:2013-01-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Discovery of potent, selective and orally bioavailable imidazo[1,5-a]pyrazine derived ACK1 inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013

227561

PDB entries from 2024-11-20

PDB statisticsPDBj update infoContact PDBjnumon