6DGK

Crystal Structure of the Non-Structural Protein 1 (NS1) effector domain W187A mutant from the A/Brevig Mission/1/1918 (H1N1) strain of Influenza A Virus

Summary for 6DGK

Entry DOI	10.2210/pdb6dgk/pdb
Descriptor	Non-structural protein 1 (2 entities in total)
Functional Keywords	influenza, ns1, effector domain, w187a, viral protein
Biological source	Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)
Total number of polymer chains	2
Total formula weight	26973.13
Authors	Kleinpeter, A.B.,Green, T.J.,Petit, C.M. (deposition date: 2018-05-17, release date: 2018-08-15, Last modification date: 2024-03-13)
Primary citation	Kleinpeter, A.B.,Jureka, A.S.,Falahat, S.M.,Green, T.J.,Petit, C.M. Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compounds. J. Biol. Chem., 293:14659-14668, 2018 Cited by PubMed: 30076219 DOI: 10.1074/jbc.RA118.004012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation