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PDB: 116 件

4V52
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Crystal structure of the bacterial ribosome from Escherichia coli in complex with neomycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-15
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
4V54
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BU of 4v54 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with ribosome recycling factor (RRF).
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-16
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
4V57
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BU of 4v57 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and neomycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D.
登録日2007-07-21
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献A steric block in translation caused by the antibiotic spectinomycin.
Acs Chem.Biol., 2, 2007
4V5Y
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BU of 4v5y by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and ribosome recycling factor (RRF).
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-19
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.45 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
4V53
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BU of 4v53 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin.
分子名称: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-16
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.54 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
4V64
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BU of 4v64 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with hygromycin B.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Shoji, S, Fredrick, K, Cate, J.H.D.
登録日2008-06-11
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis for hygromycin B inhibition of protein biosynthesis
Rna, 14, 2008
6XSR
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BU of 6xsr by Molmil
Crystal structure of GluA2 AMPA receptor in complex with trans-4-butylcyclohexane carboxylic acid (4-BCCA) inhibitor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, trans-4-butylcyclohexane-1-carboxylic acid
著者Yelshanskaya, M.V, Singh, A.K, Sobolevsky, A.I.
登録日2020-07-16
公開日2020-12-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (4.25 Å)
主引用文献Structural basis of AMPA receptor inhibition by trans-4-butylcyclohexane carboxylic acid.
Br.J.Pharmacol., 179, 2022
4V56
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BU of 4v56 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D.
登録日2007-07-21
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.93 Å)
主引用文献A steric block in translation caused by the antibiotic spectinomycin.
Acs Chem.Biol., 2, 2007
4V55
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BU of 4v55 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin and ribosome recycling factor (RRF).
分子名称: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-17
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
6ZSS
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BU of 6zss by Molmil
NMR structure of water-soluble domain of human Lynx2 (Lypd1) protein
分子名称: Ly6/PLAUR domain-containing protein 1
著者Kocharovskaya, M.V, Paramonov, A.S, Lyukmanova, E.N, Shenkarev, Z.O.
登録日2020-07-16
公開日2021-01-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors.
Int J Mol Sci, 21, 2020
7TNK
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BU of 7tnk by Molmil
Complex GNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNM
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BU of 7tnm by Molmil
Complex GNGN2 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.74 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNO
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BU of 7tno by Molmil
Complex GGGN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNJ
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BU of 7tnj by Molmil
Complex NNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNN
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BU of 7tnn by Molmil
Complex GGNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNP
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BU of 7tnp by Molmil
Complex GGGG of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNL
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BU of 7tnl by Molmil
Complex GNGN1 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
5L1H
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BU of 5l1h by Molmil
AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor GYKI53655
分子名称: (8R)-5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2
著者Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I.
登録日2016-07-29
公開日2016-10-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.801 Å)
主引用文献Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs.
Neuron, 91, 2016
5L1B
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BU of 5l1b by Molmil
AMPA subtype ionotropic glutamate receptor GluA2 in Apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Glutamate receptor 2
著者Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I.
登録日2016-07-28
公開日2016-10-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs.
Neuron, 91, 2016
5L1E
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BU of 5l1e by Molmil
AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor CP465022
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-2-(2-{6-[(diethylamino)methyl]pyridin-2-yl}ethyl)-6-fluoroquinazolin-4(3H)-one, Glutamate receptor 2
著者Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I.
登録日2016-07-29
公開日2016-10-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.37 Å)
主引用文献Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs.
Neuron, 91, 2016
5L1F
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BU of 5l1f by Molmil
AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor Perampanel
分子名称: 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2
著者Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I.
登録日2016-07-29
公開日2016-10-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs.
Neuron, 91, 2016
5L1G
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BU of 5l1g by Molmil
AMPA subtype ionotropic glutamate receptor GluA2 in complex with GYKI-Br
分子名称: (8R)-5-(4-amino-3-bromophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2
著者Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I.
登録日2016-07-29
公開日2016-10-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.507 Å)
主引用文献Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs.
Neuron, 91, 2016
4U4F
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BU of 4u4f by Molmil
Structure of GluA2* in complex with partial agonist (S)-5-Nitrowillardiine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(5-nitro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine, ...
著者Yelshanskaya, M.V, Li, M, Sobolevsky, A.I.
登録日2014-07-23
公開日2014-08-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.79 Å)
主引用文献Structure of an agonist-bound ionotropic glutamate receptor.
Science, 345, 2014
4U4G
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BU of 4u4g by Molmil
Structure of GluA2* in complex with competitive antagonist ZK 200775
分子名称: Glutamate receptor 2, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
著者Yelshanskaya, M.V, Li, M, Sobolevsky, A.I.
登録日2014-07-23
公開日2014-10-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (4.49 Å)
主引用文献Structure of an agonist-bound ionotropic glutamate receptor.
Science, 345, 2014
6PSA
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BU of 6psa by Molmil
PIE12 D-PEPTIDE AGAINST HIV ENTRY (IN COMPLEX WITH IQN17 Q577R RESISTANCE MUTANT)
分子名称: CHLORIDE ION, IQN17, PIE12 D-peptide
著者Hill, C.P, Whitby, F.G, Kay, M, Weinstock, M.
登録日2019-07-12
公開日2020-02-05
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Characterization of resistance to a potent D-peptide HIV entry inhibitor.
Retrovirology, 16, 2019

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