4U4G

Structure of GluA2* in complex with competitive antagonist ZK 200775

Summary for 4U4G

Related4U4F
DescriptorGlutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, N-ACETYL-D-GLUCOSAMINE, ... (4 entities in total)
Functional Keywordsionotropic glutamate receptor, ampa receptor, competitive antagonist, tetramer, complex, transport protein
Biological sourceRattus norvegicus (Rat)
Total number of polymer chains4
Total molecular weight373801.21
Authors
Yelshanskaya, M.V.,Li, M.,Sobolevsky, A.I. (deposition date: 2014-07-23, release date: 2014-10-22, Last modification date: 2019-12-18)
Primary citation
Yelshanskaya, M.V.,Li, M.,Sobolevsky, A.I.
Structure of an agonist-bound ionotropic glutamate receptor.
Science, 345:1070-1074, 2014
PubMed: 25103407 (PDB entries with the same primary citation)
DOI: 10.1126/science.1256508
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (4.49 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.25071.2%3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload