1WDQ
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![BU of 1wdq by Molmil](/molmil-images/mine/1wdq) | The role of an inner loop in the catalytic mechanism of soybean beta-amylase | Descriptor: | Beta-amylase, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Kang, Y.N, Adachi, M, Utsumi, S, Mikami, B. | Deposit date: | 2004-05-17 | Release date: | 2005-04-05 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Structural analysis of threonine 342 mutants of soybean beta-amylase: role of a conformational change of the inner loop in the catalytic mechanism. Biochemistry, 44, 2005
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3SW4
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![BU of 3sw4 by Molmil](/molmil-images/mine/3sw4) | |
2NTM
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2NTL
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![BU of 2ntl by Molmil](/molmil-images/mine/2ntl) | Crystal structure of PurO/AICAR from Methanothermobacter thermoautotrophicus | Descriptor: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, IMP cyclohydrolase | Authors: | Kang, Y.N, Tran, A, White, R.H, Ealick, S.E. | Deposit date: | 2006-11-07 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase. Biochemistry, 46, 2007
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1V3I
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![BU of 1v3i by Molmil](/molmil-images/mine/1v3i) | The roles of Glu186 and Glu380 in the catalytic reaction of soybean beta-amylase | Descriptor: | Beta-amylase, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | Authors: | Kang, Y.N, Adachi, M, Utsumi, S, Mikami, B. | Deposit date: | 2003-11-02 | Release date: | 2004-06-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Roles of Glu186 and Glu380 in the Catalytic Reaction of Soybean beta-Amylase. J.Mol.Biol., 339, 2004
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2NTK
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![BU of 2ntk by Molmil](/molmil-images/mine/2ntk) | Crystal structure of PurO/IMP from Methanothermobacter thermoautotrophicus | Descriptor: | IMP cyclohydrolase, INOSINIC ACID | Authors: | Kang, Y.N, Tran, A, White, R.H, Ealick, S.E. | Deposit date: | 2006-11-07 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase. Biochemistry, 46, 2007
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3SW7
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1V3H
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![BU of 1v3h by Molmil](/molmil-images/mine/1v3h) | The roles of Glu186 and Glu380 in the catalytic reaction of soybean beta-amylase | Descriptor: | Beta-amylase, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Kang, Y.N, Adachi, M, Utsumi, S, Mikami, B. | Deposit date: | 2003-11-02 | Release date: | 2004-06-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Roles of Glu186 and Glu380 in the Catalytic Reaction of Soybean beta-Amylase. J.Mol.Biol., 339, 2004
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2Z9W
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![BU of 2z9w by Molmil](/molmil-images/mine/2z9w) | Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxal | Descriptor: | 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE, Aspartate aminotransferase, GLYCEROL, ... | Authors: | Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. | Deposit date: | 2007-09-26 | Release date: | 2007-11-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J.Biol.Chem., 283, 2008
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2Z9U
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![BU of 2z9u by Molmil](/molmil-images/mine/2z9u) | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti at 2.0 A resolution | Descriptor: | Aspartate aminotransferase, GLYCEROL, SULFATE ION | Authors: | Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. | Deposit date: | 2007-09-26 | Release date: | 2007-11-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J.Biol.Chem., 283, 2008
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2Z9V
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![BU of 2z9v by Molmil](/molmil-images/mine/2z9v) | Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxamine | Descriptor: | 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, Aspartate aminotransferase, GLYCEROL, ... | Authors: | Yoshikane, Y, Yokochi, N, Yamasaki, M, Mizutani, K, Ohnishi, K, Mikami, B, Hayashi, H, Yagi, T. | Deposit date: | 2007-09-26 | Release date: | 2007-11-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J.Biol.Chem., 283, 2008
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8FE9
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![BU of 8fe9 by Molmil](/molmil-images/mine/8fe9) | Crystal structure of Ack1 kinase K161Q mutant in complex with the selective inhibitor (R)-9b | Descriptor: | Activated CDC42 kinase 1, N-[(1S)-1-benzyl-2-[(6-chloro-2-oxo-1H-quinolin-4-yl)methylamino]-2-oxo-ethyl]-4-hydroxy-2-oxo-1H-quinoline-6-carbo | Authors: | Paung, Y, Kan, Y, Seeliger, M.S, Miller, W.T. | Deposit date: | 2022-12-06 | Release date: | 2023-03-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Biochemical Studies of Systemic Lupus Erythematosus-Associated Mutations in Nonreceptor Tyrosine Kinases Ack1 and Brk. Biochemistry, 62, 2023
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4V9R
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![BU of 4v9r by Molmil](/molmil-images/mine/4v9r) | Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | Authors: | Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. | Deposit date: | 2013-12-05 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
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4V9S
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![BU of 4v9s by Molmil](/molmil-images/mine/4v9s) | Crystal structure of antibiotic GE82832 bound to 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | Authors: | Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. | Deposit date: | 2013-12-05 | Release date: | 2014-07-09 | Last modified: | 2018-06-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
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5J4C
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![BU of 5j4c by Molmil](/molmil-images/mine/5j4c) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (soaked) and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S. | Deposit date: | 2016-03-31 | Release date: | 2016-04-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome. Nucleic Acids Res., 44, 2016
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1Q6D
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![BU of 1q6d by Molmil](/molmil-images/mine/1q6d) | Crystal structure of Soybean Beta-Amylase Mutant (M51T) with Increased pH Optimum | Descriptor: | SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... | Authors: | Hirata, A, Adachi, M, Sekine, A, Kang, Y.N, Utsumi, S, Mikami, B. | Deposit date: | 2003-08-13 | Release date: | 2004-02-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Enzymatic Analysis of Soybean {beta}-Amylase Mutants with Increased pH Optimum J.Biol.Chem., 279, 2004
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1Q6C
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![BU of 1q6c by Molmil](/molmil-images/mine/1q6c) | Crystal Structure of Soybean Beta-Amylase Complexed with Maltose | Descriptor: | SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, beta-amylase | Authors: | Hirata, A, Adachi, M, Sekine, A, Kang, Y.N, Utsumi, S, Mikami, B. | Deposit date: | 2003-08-13 | Release date: | 2004-02-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural and Enzymatic Analysis of Soybean {beta}-Amylase Mutants with Increased pH Optimum J.Biol.Chem., 279, 2004
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2KDF
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![BU of 2kdf by Molmil](/molmil-images/mine/2kdf) | NMR structure of minor S5a (196-306):K48 linked diubiquitin species | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin | Authors: | Zhang, N, Wang, Q, Ehlinger, A, Randles, L, Lary, J.W, Kang, Y, Haririnia, A, Cole, J.L, Fushman, D, Walters, K.J. | Deposit date: | 2009-01-06 | Release date: | 2009-09-01 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13. Mol.Cell, 35, 2009
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2KDE
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![BU of 2kde by Molmil](/molmil-images/mine/2kde) | NMR structure of major S5a (196-306):K48 linked diubiquitin species | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin | Authors: | Zhang, N, Wang, Q, Ehlinger, A, Randles, L, Lary, J.W, Kang, Y, Haririnia, A, Cole, J.L, Fushman, D, Walters, K.J. | Deposit date: | 2009-01-06 | Release date: | 2009-09-01 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13. Mol.Cell, 35, 2009
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8HBW
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![BU of 8hbw by Molmil](/molmil-images/mine/8hbw) | Structure of human UCP1 in the ATP-bound state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, ... | Authors: | Chen, L, Kang, Y. | Deposit date: | 2022-10-31 | Release date: | 2023-06-21 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Structural basis for the binding of DNP and purine nucleotides onto UCP1. Nature, 620, 2023
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8HBV
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![BU of 8hbv by Molmil](/molmil-images/mine/8hbv) | Structure of human UCP1 in the nucleotide-free state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CARDIOLIPIN, Mitochondrial brown fat uncoupling protein 1, ... | Authors: | Chen, L, Kang, Y. | Deposit date: | 2022-10-31 | Release date: | 2023-06-21 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Structural basis for the binding of DNP and purine nucleotides onto UCP1. Nature, 620, 2023
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6NBI
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![BU of 6nbi by Molmil](/molmil-images/mine/6nbi) | Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | Descriptor: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | Deposit date: | 2018-12-07 | Release date: | 2019-04-17 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
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6NBH
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![BU of 6nbh by Molmil](/molmil-images/mine/6nbh) | Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | Descriptor: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | Deposit date: | 2018-12-07 | Release date: | 2019-04-17 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
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6NBF
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![BU of 6nbf by Molmil](/molmil-images/mine/6nbf) | Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | Descriptor: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | Deposit date: | 2018-12-07 | Release date: | 2019-04-17 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
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7RQD
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![BU of 7rqd by Molmil](/molmil-images/mine/7rqd) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site deacylated tRNA analog CACCA, P-site MTI-tripeptidyl-tRNA analog ACCA-ITM, and chloramphenicol at 2.50A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | Deposit date: | 2021-08-06 | Release date: | 2022-01-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat.Struct.Mol.Biol., 29, 2022
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