2NTL

Crystal structure of PurO/AICAR from Methanothermobacter thermoautotrophicus

Summary for 2NTL

Entry DOI	10.2210/pdb2ntl/pdb
Related	2NTK 2NTM
Descriptor	IMP cyclohydrolase, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE (3 entities in total)
Functional Keywords	alpha-beta-beta-alpha ntn hydrolase fold, hydrolase
Biological source	Methanothermobacter thermautotrophicus
Total number of polymer chains	4
Total formula weight	97475.99
Authors	Kang, Y.N.,Tran, A.,White, R.H.,Ealick, S.E. (deposition date: 2006-11-07, release date: 2007-04-24, Last modification date: 2023-08-30)
Primary citation	Kang, Y.N.,Tran, A.,White, R.H.,Ealick, S.E. A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase. Biochemistry, 46:5050-5062, 2007 Cited by PubMed: 17407260 DOI: 10.1021/bi061637j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation