7B2A
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7B2D
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7B26
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![BU of 7b26 by Molmil](/molmil-images/mine/7b26) | CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3 | Descriptor: | CirpA1, Properdin, alpha-D-mannopyranose, ... | Authors: | Lea, S.M, Johnson, S, Braunger, K. | Deposit date: | 2020-11-26 | Release date: | 2021-12-08 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure and function of a family of tick-derived complement inhibitors targeting properdin. Nat Commun, 13, 2022
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7B28
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7ALW
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4BQU
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![BU of 4bqu by Molmil](/molmil-images/mine/4bqu) | Japanin from Rhipicephalus appendiculatus bound to cholesterol: Orthorhombic crystal form | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Roversi, P, Johnson, S, Preston, S, Austyn, J.M, Nuttall, P, Lea, S.M. | Deposit date: | 2013-06-02 | Release date: | 2014-06-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks. Sci Rep, 7, 2017
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4BOE
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![BU of 4boe by Molmil](/molmil-images/mine/4boe) | Japanin from Rhipicephalus appendiculatus bound to cholesterol: Tetragonal crystal form | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | Authors: | Roversi, P, Johnson, S, Preston, S, Austyn, J.M, Nuttall, P, Lea, S.M. | Deposit date: | 2013-05-19 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks. Sci Rep, 7, 2017
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6S3S
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![BU of 6s3s by Molmil](/molmil-images/mine/6s3s) | Structure of the FliPQR complex from the flagellar type 3 secretion system of Vibrio mimicus. | Descriptor: | Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR | Authors: | Kuhlen, L, Johnson, S, Deme, J.C, Lea, S.M. | Deposit date: | 2019-06-25 | Release date: | 2020-03-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion. Nat Commun, 11, 2020
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6S3L
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![BU of 6s3l by Molmil](/molmil-images/mine/6s3l) | Structure of the core of the flagellar export apparatus from Vibrio mimicus, the FliPQR-FlhB complex. | Descriptor: | Flagellar biosynthetic protein FlhB, Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, ... | Authors: | Kuhlen, L, Johnson, S, Deme, J.C, Lea, S.M. | Deposit date: | 2019-06-25 | Release date: | 2020-03-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion. Nat Commun, 11, 2020
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6S3R
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![BU of 6s3r by Molmil](/molmil-images/mine/6s3r) | Structure of the FliPQR complex from the flagellar type 3 secretion system of Pseudomonas savastanoi. | Descriptor: | Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR | Authors: | Kuhlen, L, Johnson, S, Deme, J.C, Lea, S.M. | Deposit date: | 2019-06-25 | Release date: | 2020-03-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion. Nat Commun, 11, 2020
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5I7C
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![BU of 5i7c by Molmil](/molmil-images/mine/5i7c) | Centrosomin-motif 2 (CM2) domain of Drosophila melanogaster Centrosomin (Cnn) | Descriptor: | Centrosomin, ZINC ION | Authors: | Feng, Z, Cottee, M.A, Johnson, S, Lea, S.M. | Deposit date: | 2016-02-17 | Release date: | 2017-03-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.804 Å) | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies. Cell, 169, 2017
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5A2F
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![BU of 5a2f by Molmil](/molmil-images/mine/5a2f) | Two membrane distal IgSF domains of CD166 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CD166 ANTIGEN | Authors: | Chappell, P.E, Johnson, S, Lea, S.M, Brown, M.H. | Deposit date: | 2015-05-18 | Release date: | 2015-07-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structures of Cd6 and its Ligand Cd166 Give Insight Into Their Interaction. Structure, 23, 2015
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5A2E
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![BU of 5a2e by Molmil](/molmil-images/mine/5a2e) | Extracellular SRCR domains of human CD6 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, T-CELL DIFFERENTIATION ANTIGEN CD6 | Authors: | Chappell, P.E, Johnson, S, Lea, S.M, Brown, M.H. | Deposit date: | 2015-05-18 | Release date: | 2015-07-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structures of Cd6 and its Ligand Cd166 Give Insight Into Their Interaction. Structure, 23, 2015
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5AL7
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4BFE
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![BU of 4bfe by Molmil](/molmil-images/mine/4bfe) | Structure of the extracellular portion of mouse CD200RLa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 4, CYSTEINE, ... | Authors: | Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N. | Deposit date: | 2013-03-18 | Release date: | 2013-05-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of Cd200/Cd200 Receptor Family and Implications for Topology, Regulation, and Evolution Structure, 21, 2013
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4BF3
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![BU of 4bf3 by Molmil](/molmil-images/mine/4bf3) | ErpC, a member of the complement regulator acquiring family of surface proteins from Borrelia burgdorfei, possesses an architecture previously unseen in this protein family. | Descriptor: | 1,2-ETHANEDIOL, ERPC | Authors: | Caesar, J.J.E, Johnson, S, Kraiczy, P, Lea, S.M. | Deposit date: | 2013-03-14 | Release date: | 2013-06-05 | Last modified: | 2013-10-09 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Erpc, a Member of the Complement Regulator-Acquiring Family of Surface Proteins from Borrelia Burgdorferi, Possesses an Architecture Previously Unseen in This Protein Family. Acta Crystallogr.,Sect.F, 69, 2013
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4BFG
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![BU of 4bfg by Molmil](/molmil-images/mine/4bfg) | Structure of the extracellular portion of mouse CD200R | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, AZIDE ION, ... | Authors: | Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N. | Deposit date: | 2013-03-18 | Release date: | 2013-05-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structures of Cd200/Cd200 Receptor Family and Implications for Topology, Regulation, and Evolution Structure, 21, 2013
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4BFI
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![BU of 4bfi by Molmil](/molmil-images/mine/4bfi) | Structure of the complex of the extracellular portions of mouse CD200R and mouse CD200 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 1, ... | Authors: | Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N. | Deposit date: | 2013-03-19 | Release date: | 2013-05-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | Structures of Cd200/Cd200 Receptor Family and Implications for Topology, Regulation, and Evolution Structure, 21, 2013
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4CMM
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![BU of 4cmm by Molmil](/molmil-images/mine/4cmm) | Structure of human CD47 in complex with human Signal Regulatory Protein (SIRP) alpha v1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUKOCYTE SURFACE ANTIGEN CD47, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 | Authors: | Hatherley, D, Lea, S.M, Johnson, S, Barclay, A.N. | Deposit date: | 2014-01-16 | Release date: | 2014-02-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Polymorphisms in the Human Inhibitory Signal-Regulatory Protein Alpha Do not Affect Binding to its Ligand Cd47. J.Biol.Chem., 289, 2014
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5LHY
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![BU of 5lhy by Molmil](/molmil-images/mine/5lhy) | PB3 Domain of Human PLK4 (apo) | Descriptor: | Serine/threonine-protein kinase PLK4 | Authors: | Cottee, M.A, Johnson, S, Lea, S.M. | Deposit date: | 2016-07-13 | Release date: | 2017-03-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies. Biol Open, 6, 2017
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5MWE
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![BU of 5mwe by Molmil](/molmil-images/mine/5mwe) | Complex between the Leucine Zipper (LZ, residues 490-567) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) | Descriptor: | 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, Centrosomin, ... | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | Deposit date: | 2017-01-18 | Release date: | 2017-06-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies. Cell, 169, 2017
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5MW9
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![BU of 5mw9 by Molmil](/molmil-images/mine/5mw9) | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form | Descriptor: | Centrosomin, ZINC ION | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | Deposit date: | 2017-01-18 | Release date: | 2017-06-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies. Cell, 169, 2017
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5MVW
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![BU of 5mvw by Molmil](/molmil-images/mine/5mvw) | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Centrosomin, ... | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | Deposit date: | 2017-01-17 | Release date: | 2017-06-28 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies. Cell, 169, 2017
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5MW0
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![BU of 5mw0 by Molmil](/molmil-images/mine/5mw0) | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form | Descriptor: | Centrosomin, ZINC ION | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | Deposit date: | 2017-01-17 | Release date: | 2017-06-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies. Cell, 169, 2017
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5HCC
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![BU of 5hcc by Molmil](/molmil-images/mine/5hcc) | Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Dermacentor andersoni RaCI3. | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Jore, M.M, Johnson, S, Lea, S.M. | Deposit date: | 2016-01-04 | Release date: | 2016-03-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structural basis for therapeutic inhibition of complement C5. Nat.Struct.Mol.Biol., 23, 2016
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